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World Cup Qualifiers Uruguay vs. Argentina – Injury News, Injury Update, Predicted Line-ups and More

Abhinav Goel

Get the injury news, predicted lineups, and key match details for World Cup Qualifying game - Argentina vs. Uruguay.

Argentina continue their journey for 2026 FIFA World Cup qualification with a blockbuster clash against Uruguay in Montevideo on Friday night. The reigning World Cup champions head into the game in strong form and will be eager to solidify their position at the top of the CONMEBOL standings.

Having collected 25 points from their qualifying campaign so far, Lionel Scaloni’s side sit comfortably in first place. With a solid defensive unit and star-studded attack led by Lionel Messi, Argentina remain the team to beat in South America. La Albiceleste secured a narrow 1-0 win over ninth-placed Peru in their last qualifying match, maintaining their hold on the top spot. Meanwhile, Uruguay delivered an impressive performance by holding Brazil to a 1-1 draw on the road.

Victory in Uruguay would see Argentina take an enormous step towards booking their ticket for the 2026 World Cup. However, Uruguay are enjoying a revival of their own under Marcelo Bielsa. Sitting in second place with 20 points, Uruguay will present a formidable challenge for Argentina. A win for Uruguay would not only boost their World Cup qualification hopes but also cut Argentina’s lead at the top of the standings to just two points. Uruguay have already proven their ability to beat the world champions, having defeated Argentina earlier in the qualifying campaign, a result that shocked many.

Argentina Injury News

Argentina’s talisman Lionel Messi was not included in Argentina’s squad for these qualifiers after medical scans revealed a minor adductor injury. Messi sustained the injury during Inter Miami’s 2-1 victory over Atlanta United. Alongside Messi, Lionel Scaloni will also be without several other key players for the clash against Uruguay. Paulo Dybala (Roma), Giovani Lo Celso (Real Betis), and Gonzalo Montiel (River Plate) have all been ruled out due to injury concerns.

Inter Milan striker Lautaro Martinez has also withdrawn from the squad after suffering a hamstring injury, dealing another blow to Argentina’s attacking options.

Argentina probable starting lineup:

Martinez; Molina, Romero, Otamendi, Tagliafico; De Paul, Mac Allister, Fernandez; Correa, Gonzalez, Alvarez

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Uruguay Injury News

Manchester United midfielder Manuel Ugarte will miss Friday’s clash against Argentina due to suspension, having picked up an accumulation of yellow cards during the qualifying campaign. Meanwhile, Ronald Araujo is set for a long-awaited return to international action. The defender is expected to make his first appearance for Uruguay since July, after being sidelined for the team’s last six World Cup qualifiers due to injury.

Uruguay probable starting lineup:

Rochet; Nandez, R. Araujo, Gimenez, Saracchi; Valverde, Bentancur; Pellistri, Aguirre, M. Araujo; Nunez

Uruguay vs. Argentina World Cup Qualifying Final Betting Odds

Odds via BetMGM

TeamsMoneylineTotal Goals
Uruguay Win: +145
Draw: +190
Over 2.5: +155
Under 2.5: -227
Argentina Win: +210
Draw: +190
Over 3.5: +400
Under 3.5: -666
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I am a soccer writer at The PlayOffs, covering everything from match analysis to transfer buzz and tactical deep dives. Ever since I was a kid, soccer has been more than just a sport to me—it’s been an obsession. Playing and watching the game from a young age fueled my passion, eventually leading me into the world of sports media and betting. Now, I get to analyze the sport I love and bring the latest updates to fans worldwide.

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