The Serie A slate from February 6–9, 2026, arrives with significant implications at both ends of the table. Napoli will continue their push at the top with a demanding away trip to Genoa. It’s been a venue that often complicates matters through physicality and compact defending.
Juventus will host Lazio in a clash shaped by European qualification pressure and recent tactical evolution. Meanwhile, Inter Milan travel to Sassuolo in a matchup that historically produces open phases and attacking opportunities from wide areas. Nine games throughout the matchweek will have some implications all around the table.
For more analysis across Italy and Europe, visit our main soccer predictions and Serie A betting tips hub, but for now, scroll on for today’s best bets.
Our Serie A Best Picks of Matchday 24
Match
Market & Pick
Odds & Book
Genoa vs Napoli
Napoli to Win
-310 via Fanduel
Juventus vs Lazio
Total Goals: Over 1.5
-275 via BetMGM
Sassuolo vs Inter Milan
Federico Dimarco to Score or Assist
+180 via FanDuel
Odds from FanDuel and BetMGM, accurate as of Saturday morning ET. Serie A lines can move quickly on matchday, so always check the latest prices before betting.
Best Bet #1 – Genoa vs Napoli: Napoli to Win
Market
Pick
Odds & Book
Match Result
Napoli to Win
-310 via Fanduel
Napoli will travel to the Stadio Luigi Ferraris on Friday, February 6 to face a Genoa side known for their defensive organization at home but limited attacking output. Over their last ten matches across competitions, Napoli have averaged approximately 2.0 expected goals per game while conceding just over 1.0 xGA.
Genoa, in contrast, have generated under 1.1 xG per match during the same span. Much of their attacking play has relied on set pieces rather than sustained possession. Napoli’s away form has remained stable, supported by midfield control and efficient ball progression through the half-spaces.
Their ability to maintain pressure has limited opponents to low shot volumes. It will be a critical factor against a Genoa side that struggles to create chances when forced to defend deep for extended periods. Head-to-head history also favors Napoli. They have regularly imposed their rhythm in recent meetings despite Genoa’s physical approach.
Fixture congestion plays a role, but Napoli’s squad rotation has been measured, especially in defensive areas. The overwhelmingly short moneyline reflects both the quality gap and Genoa’s limited scoring threat. Given Napoli’s superior xG differential and tactical adaptability on the road, backing them to win aligns with both head-to-head records and recent stats.
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Best Bet #2 – Juventus vs Lazio: Total Goals Over 1.5
Market
Pick
Odds & Book
Total Goals
Over 1.5
-275 at BetMGM
Juventus will welcome Lazio at the Allianz Stadium on Saturday, February 7. The fixture will be shaped by evolving attacking approaches from both sides. Juventus’ last 10 games show an average of around 1.7 xG created per game, with an xGA close to 0.9. Meanwhile, Lazio have averaged around 1.6 xG per match.
But they’ve conceded closer to 1.4 xGA. Recent head-to-head meetings between these two have produced at least two goals with regularity Juventus have increasingly targeted wide overloads and late midfield runs, which has increased shot quality inside the box. Lazio’s counterattacking style is built on vertical passing and quick switches.
It often generates clear chances even when possession is limited. While neither side consistently produces high-scoring matches, the threshold of over 1.5 goals accounts for Juventus’ controlled tempo and Lazio’s attacking intent. The short moneyline reflects a conservative market stance, but xG trends and matchup dynamics suggest two goals can be expected.
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Best Bet #3 – Sassuolo vs Inter Milan: Federico Dimarco to Score or Assist
Market
Pick
Odds & Book
Score or Assist
Federico Dimarco
+180 at FanDuel
Inter Milan will travel to the Mapei Stadium on Sunday, February 8. They will face a Sassuolo side that often concedes space in wide areas. Inter’s recent form shows an attacking output near 2.1 xG per match across their last 10 foxtures. Meanwhile, Sassuolo have allowed over 1.7 xGA per game
Federico Dimarco’s role in Inter’s system makes him a strong candidate for direct goal involvement. Over his last 10 appearances, he has averaged more than 0.35 expected goal contributions per 90 minutes. His delivery accuracy and timing have been consistent strengths, especially against teams that defend narrowly.
Sassuolo’s defensive structure often leaves space behind the fullbacks. Inter deliberately target through overlapping runs in that area. The market prices depict Dimarco as a secondary contributor rather than a focal attacker. Given his recent production and the matchup-specific advantages, backing him to score or assist offers value relative to Inter’s broader attacking dominance.
Serie A Best Bets for Matchday 24 Recap – February 6-9, 2026
Best Bet #1: Genoa vs Napoli – Napoli to Win (-310 at FanDuel)
Best Bet #2: Juventus vs Lazio – Total Goals Over 1.5 (-275 at BetMGM)
Best Bet #3: Sassuolo vs Inter Milan – Federico Dimarco to Score or Assist (+180 at FanDuel)
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