Jun 9, 2024; Paris, France; Alexander Zverev of Germany returns a shot during the menÕs final match against Carlos Alcaraz of Spain on day 15 of Roland Garros at Stade Roland Garros.

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Alexander Zverev vs. Lorenzo Musetti Head to Head, Prediction and Betting Odds for ATP Italian Open 2025 Quarterfinal

No. 2 vs No. 8 seed at the Eternal City

Jun 9, 2024; Paris, France; Alexander Zverev of Germany returns a shot during the menÕs final match against Carlos Alcaraz of Spain on day 15 of Roland Garros at Stade Roland Garros.

No. 2 seed Alexander Zverev, who is a two-time winner of the Italian Open, faces home favourite Lorenzo Musetti in the 2025 Internazionali BNL d’Italia quarterfinals. Both players won their Round of 16 encounters in straight sets, resulting in a mouth-watering night match on Wednesday’s Centre Court action.

Alexander Zverev vs Lorenzo Musetti Preview

Zverev is entering a crucial part of his 2025 season. The German starlet won the Italian Open 2024 trophy, meaning that he is defending 1000 points at the event this year. He is also the runner-up at Roland Garros from last year – having lost to Carlos Alcaraz in the final. ‘Sascha’ Zverev has one title to his name in 2025 – the BMW Open in Munich. He defeated Ugo, Gaubas and Fils to reach the quarterfinals. With a 13-4 clay court record and nearly 78% service game winning ratio on this surface, the 28-year-old can beat anyone on his day.

In comparison, Musetti has a similar 13-3 record on the red dirt in 2025. The Italian reached the final in Monte Carlo, before making the semifinals at the Mutua Madrid Open. With 37% breaks achieved (44 out of 119), Musetti ranks just outside the world’s Top-10 in terms of break point conversion rate on clay. The World No. 9 is searching for his third career championship, and first of the year. He beat Virtanen, Nakashima and Medvedev to book his spot in the last eight.

Alexander Zverev vs Lorenzo Musetti Head to Head Record

The head to head between Zverev and Musetti is 2-1 in favour of the 23-year-old Italian star. While Zverev won the first encounter between them, Musetti has made a telling comeback in this rivalry.

After Wednesday’s quarterfinal at the Italian capital, three out of four clashes between these players will have been on outdoor clay courts. While they are yet to lock horns at Grand Slam level, Musetti denied reigning gold medalist Zverev another success at the 2024 Paris Olympics.

Event	Round	Winner	Score
2024 Vienna	Quarterfinal	Lorenzo Musetti	2-6 7-6(5) 6-4
2024 Paris Olympics	Quarterfinal	Lorenzo Musetti	7-5 7-5
2022 Madrid	Round of 16	Alexander Zverev	6-3 1-0 RET.

Alexander Zverev vs Lorenzo Musetti Career Comparison

Alexander Zverev	Category	Lorenzo Musetti
0	Grand Slams	0
24	ATP Singles Titles	2
2	ATP Doubles Titles	0
7	Masters-1000 Titles	0
6	ATP-500 Titles	1
Gold (Tokyo 2020)	Olympics Best Performance	Bronze (Paris 2024)
No. 2	Current World Ranking	No. 9

Alexander Zverev vs Lorenzo Musetti Italian Open 2025 Prediction

Zverev’s got a special fan club in the house today 🟡🔴#IBI25 pic.twitter.com/B4K4OTXb3l
— Internazionali BNL d'Italia (@InteBNLdItalia) May 13, 2025

Despite what the odds might suggest, Zverev knows the conditions in Rome better than most players left in the draw. The German enjoys the slower nature of courts, and has been serving well too. Musetti will need to apply pressure on the second serve of the three-time Grand Slam finalist – expect the Italian to target the corners and use the crowd to his advantage.

Prediction: Alexander Zverev in three sets.

Alexander Zverev vs Lorenzo Musetti Italian Open 2025 Betting Odds

As per the pre-match money line probability, Lorenzo Musetti has a 59% chance of entering the final four. The match is predicted to go into a third set, with the home favourite possibly emerging victorious.

Alexander Zverev Win: -145

Lorenzo Musetti Win: +118

(According to BetMGM)

Alexander Zverev

ATP

Betting

Carlos Alcaraz

Italian Open

Jack Draper

Lorenzo Musetti

Paris Olympics

Roland Garros

Tennis

Sankalp Harikrishnan

A passionate sports fan through and through, I am currently pursuing my MA in Global Sports Journalism. I specialise in tennis and football writing at The Playoffs News, and I have prior experience working at EssentiallySports and Sportskeeda. Born and raised in Bengaluru, India, sport was my safe space right from my childhood. After trying my hand at multiple sports and representing my educational institutions in cricket, badminton and table tennis, I found sports media to be my calling.