The upcoming Serie A fixture sees reigning champions Napoli return to the Stadio Diego Armando Maradona with defending the top spot firmly in mind as they face Como 1907. The hosts have restored their fine form, while their visitors arrive on the back of an impressive unbeaten stretch.
Napoli reclaimed the summit with a pivotal win against Inter Milan and followed this up with another narrow victory. Meanwhile, Como’s rise under Cesc Fàbregas has been notable, particularly given their away struggles and leap into serious challengers.
| Bets | Status | Moneyline |
| Total Goals | Under 2.5 | -150 |
| Total Shots | Over 24.5 | -118 |
| Total Shots on Target | Over 7.5 | -138 |
| Total Corners | Under 7.5 | +170 |
| Total Cards | Under 3.5 | +114 |
| Napoli Saves | Over 3.5 | +240 |
| Como Saves | Over 4.5 | +200 |
Napoli are missing key figures such as Romelu Lukaku and Kevin De Bruyne through injury, while keeper Alex Meret also remains unavailable. On a brighter note, midfielder Stanislav Lobotka is back in contention after recovering from muscular issues and might feature from the bench. Forward Rasmus Højlund is also pushing for a start after recent fitness progress. Manager Antonio Conte will still expect the same intensity and pressing style even with personnel changes.
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Como are dealing with a smaller injury list but still facing absences, including veteran Sergi Roberto and Alberto Dossena, both sidelined. Meanwhile, attackers Arnaut Danjuma and Hugo Duro—each with four league goals—are expected to start. Defensive stalwart José Gayà will marshal the backline, supported by midfield presence around Baptiste Santamaria. Head coach Cesc Fàbregas will rely on Como’s transitional approach and recent upward momentum to challenge Napoli.
Napoli remain the clear favourites and are intent on securing all three points at home, but injuries to key attacking figures suggest they may not run away with the total goals tally. Their recent victory margins have often been narrow—such as a 1-0 win at Lecce despite dominating. Como, though in good form, have struggled to score away, averaging under one goal per trip. Together, these dynamics support a tighter script and validate the under 2.5 goals market.
Hojlund is steadily regaining fitness and may start against Como, bringing his promise of physical presence and attacking threat into Napoli’s forward line. While he might not yet be at full sharpness, his involvement in the build-up and likelihood of being the primary outlet give decent value at +200. Napoli’s attacking setup, with weakened options, may rely on his fresh legs to break through.
McTominay has been influential in Napoli’s midfield since arriving and has shown an increasing tendency to push forward into goal-creating positions. With De Bruyne unavailable, McTominay is likely to have added responsibility in attack and chance-creation. His dual role—scoring and assisting—makes the +170 odds for a goal contribution realistic in this matchup.
| Picks | Moneyline |
| Rasmus Hojlund to score first | +480 |
| Frank Anguissa to score anytime | +330 |
| Leonardo Spinazzola to assist anytime | +550 |
| Scott McTominay to either score or assist | +170 |
| Alberto Moreno to see a card | +165 |
| Alberto Moreno to foul | -195 |
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Napoli’s return to winning ways and strong home record suggest they will eke out a controlled victory. Napoli will dominate possession and convert one set-piece or counter-break, while Como may struggle to break their resistance.
Como’s rise is impressive but their away form and scoring limitations reduce their threat potential. Given Napoli’s recent 1-0 wins and the necessity to manage fitness ahead of their Champions League campaign, a 2-0 scoreline looks the most plausible.
The Napoli vs Como Serie A clash is on November 1, 2025, at the Diego Armando Maradona Stadium, Naples, Italy.
Napoli are favorites to win with a moneyline at -105, to draw at +220 and for Como to win at +320.
Rasmus Hojlund to score anytime: +210
Leonardo Spinazzola to assist anytime: +500
Scott McTominay to either score or assist: +190
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