Mar 23, 2025; Miami, FL, USA; Francisco Cerundolo (ARG) reaches for a forehand against Tommy Paul (USA)(not pictured) on day six of the Miami Open at Hard Rock Stadium. Mandatory Credit: Geoff Burke-Imagn Images

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Jannik Sinner vs. Francisco Cerundolo Preview, Head-to-Head, Prediction and Betting Odds for ATP Italian Open 2025 Round of 16

Can Sinner get past the first real test after his return?

With this year’s Italian Open now reaching the round of 16 stage on the ATP tour, number one seed Jannik Sinner continues his quest for a first title following his comeback against Argentina’s Francisco Cerundolo.

Both players have played quality tennis to reach this stage of the tournament, but now they must raise their game as this duel is likely to be a tough one.

Jannik Sinner vs Francisco Cerundolo Preview

Jannik Sinner would be pleased with the way his Italian Open campaign is shaping off. Still dusting off some of the rust, Sinner has done well in his two matches, making light work of

Mariano Navone and Jesper De Jong in the second and third rounds respectively, following a first-round bye.

Argentine Cerundolo is enjoying a good season on tour thus far, with wins against multiple top players despite the inability to win a title. He has reached far in tournaments with a number of quarterfinal or better results, and has in fact reached consecutive semi-finals in Munich and Madrid.

Jannik Sinner vs Francisco Cerundolo Head-to-Head Record

Jannik Sinner and Francisco Cerundolo have met 4 times so far in their professional careers. Today’s meeting marks their fifth encounter, which currently stands at 2 a piece.

This rivalry started in 2022, and interestingly, the players met three times in total that year. Cerundolo won their first meeting in Miami before Sinner came back to win the next two matches at the Davis Cup and in Vienna.

The most recent tie went the way of the Argentine, which was played in 2023, exactly at this event in Rome.

Year	Event	Round	Winner	Score
2023	ATP Masters 1000 Rome	Round of 16	Francisco Cerundolo	6⁽³⁾-7, 6-2, 6-2
2022	Vienna	Round of 16	Jannik Sinner	7-5, 6-3
2022	ITA vs ARG Finals Group A RR	Round Robin	Jannik Sinner	7-5, 1-6, 6-3
2022	ATP Masters 1000 Miami	Quarterfinal	Francisco Cerundolo	4-1 RET

Jannik Sinner after beating De Jong in Rome

“Francisco Cerundolo next… No disrespect to the players you’ve played so far but how much of a step up will he be for you on your comeback?”

Jannik: “You know, every day, every challenge is a tough one. Of course last time I played… pic.twitter.com/olqXyvTxf0
— The Tennis Letter (@TheTennisLetter) May 12, 2025

Also Read: Italian Open 2025 ATP Round of 16 Schedule – Who Faces Whom In the Italian Open Round of 16?

Jannik Sinner vs Francisco Cerundolo Career Comparison

Although both players turned pro in 2018, their careers have taken diverging paths as far as overall success is concerned. Sinner, the world number one, has many major titles in his kitty, especially 3 Grand Slams, whereas Cerundolo has not come close to that level of success.

Jannik Sinner	Category	Francisco Cerundolo
1	Ranking	18
270-80	Career W-L	126-99
7-0	YTD W-L	24-10
19	Career Titles	3
3	Grand Slams	0
1	YTD Titles	0

Jannik Sinner vs Francisco Cerundolo Italian Open 2025 Prediction

Despite Sinner being the world number one and still playing good tennis after three months of being out of the sport, this will not be an easy match. Cerundolo has been in great form, and he is currently enjoying a great stint on clay.

If Sinner still looks rusty against a quality opponent such as the Argentine, then Cerundolo has every chance at causing an upset here.

Prediction: Cerundolo in three sets

Jannik Sinner vs Francisco Cerundolo Italian Open 2025 Betting Odds

The odds heavily favor the Italian to pull off the win in this encounter, mostly as Sinner looks in top form, and he will be egged on by his home crowd.

Jannik Sinner Win: 1/4

Francisco Cerundolo Win: 14/5

(According to BetMGM)

2025 Rome Masters

Francisco Cerundolo

Italian Open

Jannik Sinner

Devavrat Kulkarni

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