Key injury updates ahead of Week 5 clash between Bills and Patriots
As the 2025 NFL season approaches Week 5, the primetime Sunday Night Football spotlight falls on Orchard Park, where the unbeaten Buffalo Bills host the New England Patriots. Buffalo comes in at 4-0, riding a wave of dominant performances, while New England, at 2-2, seeks to prove they can contend with the division leaders. Both teams bring momentum, injury concerns, and contrasting trajectories into this AFC East clash, making this matchup one of the most compelling of the week.
Below is the injury report for the Buffalo Bills for Week 5 action against the New England Patriots.
| Player | Position | Injury | Status |
|---|---|---|---|
| Dorian Strong | CB | Neck (DNP) | Out |
| Dorian Williams | LB | Knee (DNP) | Out |
| Spencer Brown | OL | Calf (LP) | Questionable |
| Matt Milano | LB | Pectoral (LP) | Questionable |
| Ed Oliver | DT | Ankle (LP) | Questionable |
| T.J. Sanders | DT | Knee (LP) | Questionable |
| Jackson Hawes | TE | Ankle (FP) | – |
| Joey Bosa | DE | Not Injury Related / Rest (FP) | – |
The Bills face notable absences that could impact their defensive and offensive balance. CB Dorian Strong (neck) and LB Dorian Williams (knee) are ruled out, removing depth in pass coverage and run defense. DT T.J. Sanders (knee), RT Spencer Brown (calf), DT Ed Oliver (ankle), and LB Matt Milano (pectoral) are all questionable, meaning Buffalo may enter Sunday night without key defensive assets. Milano’s potential absence, in particular, could hinder Buffalo’s ability to disrupt New England’s rushing game.
Buffalo has emerged as the AFC’s early powerhouse, boasting a perfect start and top seed positioning owing to wins over Baltimore, New York, Miami, and New Orleans. Their ability to close games, like a narrow 41-40 Week 1 win over the Ravens, dominates on the ground and makes them formidable at home. As Week 5 approaches, Buffalo seeks to maintain dominance and extend their streak against a Patriots team hungry to prove they belong.
Below is the injury report for the New England Patriots for Week 5 action against the Buffalo Bills.
| Player | Position | Injury | Status |
|---|---|---|---|
| K’Lavon Chaisson | LB | Knee (DNP) | Out |
| Carlton Davis III | CB | Illness (FP) | Questionable |
| Jahlani Tavai | LB | Calf (FP) | Questionable |
| Milton Williams | DT | Ankle (LP) | Questionable |
| Christian Barmore | DT | Not Injury Related / Other (FP) | – |
| Will Campbell | T | Shoulder (FP) | – |
| Jaylinn Hawkins | S | Hamstring (FP) | – |
| Marte Mapu | LB | Neck (FP) | – |
| Mike Onwenu | G | Shoulder (FP) | – |
| Jared Wilson | G | Ankle / Knee (FP) | – |
New England’s injury picture is centered on questionable and limited participants in key defensive roles. CB Carlton Davis III (illness) and DT Milton Williams (ankle) stand out as players whose availability could significantly alter matchups. Davis’ absence would weaken the Patriots’ secondary against Buffalo’s prolific passing attack, while Williams not playing could hurt defensive line pressure. LB Jahlani Tavai (calf) is also questionable, which would further limit linebacker depth against Buffalo’s dynamic offense.
New England’s 2025 campaign has been a mixed bag, starting 2-2 but ending Week 4 with a statement 42-13 victory over Carolina. Losses to the Raiders and Steelers were balanced by a win at Miami, showing flashes of promise from their rookie-led offense and opportunistic defense. Positioned second in the AFC East, the Patriots enter Orchard Park as underdogs, but recent form and a healthy dose of confidence make them a dangerous opponent in primetime.
Image Credits: Imagn Images
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