Mandatory Credit: Jayne Kamin-Oncea-Imagn Images

NFL Game Tonight – Where To Watch LA Rams vs San Francisco 49ers Game Tonight? Week 5 Thursday Night Football Tonight TV Channel, Kick-Off Time and More

Mandatory Credit: Jayne Kamin-Oncea-Imagn Images

In the heart of the NFC West, the Los Angeles Rams (3-1) welcome the San Francisco 49ers (3-1) to SoFi Stadium on Thursday Night Football, which is a pivotal Week 5 clash that could reshape the division standings. Both teams boast explosive offenses, but the Rams are the favorites to win, riding a hot streak with Matthew Stafford’s arm (1,114 yards and 8 TDs) torching defenses. Sean McVay’s squad has been flaring well to start the season, with their only loss coming against the Philadelphia Eagles, who are still the team to beat.

The 49ers, however, arrive battered on a short week, after suffering a loss against the Jacksonville Jaguars in Week 4. What’s worse? According to the latest reports, their QB1 Brock Purdy is out for tonight’s game, going back to their backup Mac Jones to deliver. Luckily for the 49ers, their schedule is very favorable for them, but even if they make the playoffs, we expect them to bounce out of the wild card round. However, tonight, the are going to go up against the toughest competition they’ve faced so far, making it a difficult challenge for them.

Week 5 Thursday Night Football Tonight – Where To Watch Rams vs 49ers Game Tonight?

The Los Angeles Rams are set to take on the San Francisco 49ers for Week 5’s Thursday Night Football, at SoFi Stadium (home of the Rams). You can catch the action live on Prime Video at 8:15 p.m. ET.

Local TV Channels will also be airing the contest;

San Francisco: KTVU (FOX 2)
Los Angeles: KTTV (FOX 11)

Game Details;

Location: SoFi Stadium (Inglewood, California)
Date: Thursday, October 2, 2025
Time: 8:15 p.m. ET
Stream: Prime Video

First NFC West matchup in 24 hours!!

🎟️ https://t.co/14wuvZT6XW pic.twitter.com/gUatw7tvds
— Los Angeles Rams (@RamsNFL) October 2, 2025

Rams vs 49ers Head to Head Record- Who Holds the Advantage?

In this NFC West rivalry, the 49ers hold the edge, leading the series 78-71-3. However, the L.A. Rams are slowing starting to catchup as they won their last three meetings.

Going on a trip 💼@united | #FTTB pic.twitter.com/t0sHoyvXhR
— San Francisco 49ers (@49ers) October 2, 2025

From 2019 to 2021, the 49ers and Kyle Shanahan swept the Rams six straight times, and is currently 10-6 against the Rams and Sean McVay. While that may have been the case a couple of years ago, the Rams have significantly improved and, as mentioned earlier, have won three straight against the 49ers.

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Eric Divakaran

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I cover the National Football League and things cannot get better than that. I always dreamed to play football or basketball professionally since I’m built like a Running Back. But now that I can’t, since I’m technically in the “Unc” age, I thought why not pick a career in sports industry? So here I am, doing what I love, and hoping that the Commanders win the Super Bowl. I give love to players when it’s due, but can be critical about their performances at the same time. Enough about me, now let my articles do all the talking.