Mar 30, 2025; Miami, FL, USA; Jakub Mensik (CZE) waves to the crowd while walking onto the court before his match against Novak Djokovic (SRB)(not pictured) in the men's singles championship of the Miami Open at Hard Rock Stadium.

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Jakub Mensik vs. Reilly Opelka Preview, Prediction and Betting Odds for ATP Eastbourne Open 2025 Round of 16

First meeting between the two ATP giants.

No. 3 seed Jakub Mensik opens his account at the 2025 Lexus Eastbourne Open with a tough Round of 16 encounter against big serving Reilly Opelka of the United States of America. Both players were knocked out at the same stage in their previous tournament – the HSBC Championships in London. The winner of this match-up will take on either Alejandro Davidovich Fokina or James Duckworth in the quarterfinals.

Jakub Mensik vs Reilly Opelka Match Preview

Jakub Mensik has arguably been the breakout youngster of the ATP season. The 19-year-old currently stands tall with a career-high ranking of No. 17 in the world. Mensik reached back-to-back quarterfinals in Brisbane and Auckland to start 2025, before a series of average outings. His claim to fame arrived at the Miami Masters, where he beat Novak Djokovic to capture his maiden trophy. He enters this match with a 78.6% win rate on grass court service games, and a 1-1 record this year.

On the other hand, Reilly Opelka has gone 5-2 across two competitions on this surface. This includes a run through qualifying into the semifinals at the Libema Open – where he defeated former US Open champ Daniil Medvedev along the way. The 6’11” powerhouse relies on his scintillating first serve to land the knockout blows for him more often than not. He will be looking to improve his 16-12 record in the second half of the season.

Too Tough! 👏

Reilly Opelka defeats British qualifier Loffhagen 7-6 3-6 7-6 to move on in Eastbourne#LexusEastbourneOpen pic.twitter.com/NY73s5SUv8
— Tennis TV (@TennisTV) June 24, 2025

Mensik and Opelka have never faced each other on the ATP circuit. As a result, their head-to-head currently stands at 0-0 so far. Wednesday’s pre-quarterfinal will be their first meeting.

Jakub Mensik vs Reilly Opelka Career Comparison

Jakub Mensik	Category	Reilly Opelka
0	Grand Slams	0
1	ATP Singles Titles	4
0	ATP Doubles Titles	1
1	Masters-1000 Titles	0
R2 (Paris 2024)	Olympics Best Performance	–
No. 17	Current World Ranking	No. 72

Jakub Mensik vs Reilly Opelka ATP Eastbourne Open 2025 Prediction

There will be very few breaks of serve in this ace-heavy encounter. The match could be determined by who manages to win the neutral rallies. On paper, Mensik is more likely to test the American’s court coverage and emerge victorious. However, if Opelka finds a consistent rhythm and a second shot to back it up, it will be extremely hard to take him out of the draw.

Prediction: Jakub Mensik in three sets.

Jakub Mensik vs Reilly Opelka ATP Eastbourne Open 2025 Betting Odds

According to the initial trends, Mensik starts as the favourite against the underdog Opelka. He has almost double the chances of progressing into the last eight when compared to his 27-year-old counterpart. Here are the match odds (as per BetMGM):

Jakub Mensik Win: 11/20
Reilly Opelka Win: 29/20

Expect a minimum of 1-2 tiebreak sets in this match. There will be quick holds of serve, and the average rally length is expected to be 3-4 shots. Here are the match-specific odds for Mensik vs Opelka (as per BetMGM):

Total Games Over 25.5: 17/20
Total Sets Over 2.5: 5/4
Total Number of Tiebreaks Over 0.5: 4/11

(According to BetMGM: BetMGM offers exclusive promo codes, bonus deals and accurate odds for users upon signing up. Use BetMGM to ace your betting game in all sports!)

ATP

Betting

Eastbourne Open

Jakub Mensik

Novak Djokovic

Reilly Opelka

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Wimbledon

Sankalp Harikrishnan

A passionate sports fan through and through, I am currently pursuing my MA in Global Sports Journalism. I specialise in tennis and football writing at The Playoffs News, and I have prior experience working at EssentiallySports and Sportskeeda. Born and raised in Bengaluru, India, sport was my safe space right from my childhood. After trying my hand at multiple sports and representing my educational institutions in cricket, badminton and table tennis, I found sports media to be my calling.