Jun 3, 2024; Paris, France; Holger Rune of Denmark reacts to a point during his match against Alexander Zverev of Germany on day nine of Roland Garros at Stade Roland Garros.

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Holger Rune vs. Francisco Comesana Head to Head Record, Preview and Prediction for ATP Italian Open 2025 Round-2

Rune won the Barcelona Open 2025 title.

Jun 3, 2024; Paris, France; Holger Rune of Denmark reacts to a point during his match against Alexander Zverev of Germany on day nine of Roland Garros at Stade Roland Garros.

Fresh off his Barcelona Open Banc Sabadell title charge, Holger Rune is set to entertain fans at the 2025 Italian Open in Rome. The Danish prodigy begins his campaign with a tricky encounter against Francisco Comesana of Argentina. The 24-year-old beat Daniel Altmaier 6-1 7-5 in Round-1. On the other hand, Rune was forced to retire from the Madrid Masters due to a right quad injury – making his Foro Italico return a crucial pit stop before Roland Garros.

Holger Rune has captured a solitary title in 2025 – the Barcelona Open. The 22-year-old Dane outplayed World No. 3 Carlos Alcaraz in the final. Rune was also the runner-up at Indian Wells this year, falling short vs newly crowned World No. 5 Jack Draper in the summit clash. He has a 15-8 record this year. Rune was the finalist at the Internazionali d’Italia in 2023, but lost in Round-3 to Sebastian Baez last year.

The Italian Open could promise to be a happy hunting ground for Francisco Comesana. The World No. 63 made the Spanish crowd stand up and take notice when he overpowered Pedro Martinez and Arthur Fils en route to a Round of 32 showing in Madrid. Comesana reached the final at the Oeiras Open 4, and made the semifinal in Rio this year.

Holger Rune vs Francisco Comesana Head to Head Record

Holger Rune and Francisco Comesana share a 0-0 head to head record so far. The Italian Open Round of 64 clash will be the first time these two stars take to court against each other.

Holger Rune taking the traditional Champion's Dive after winning Barcelona.

Great to have him back at his best. ❤ pic.twitter.com/exbUrggEED
— The Tennis Letter (@TheTennisLetter) April 20, 2025

Holger Rune vs Francisco Comesana Title Comparison

Holger Rune	Category	Francisco Comesana
0	Grand Slams	0
5	ATP Singles Titles	0
0	ATP Doubles Titles	0
1	Masters-1000 Titles	0
1	ATP-500 Titles	0
–	Olympics Best Performance	–
No. 10	Current World Ranking	No. 63

Holger Rune vs Francisco Comesana Italian Open 2025 Prediction

Under the warm conditions in Rome, this match-up will be a test of endurance for both players. We saw Rune using the backhand to forehand drop shot tactic brilliantly against Karen Khachanov in Barcelona. The No. 9 seed will look to dictate play from the back of the court. Provided he is to pull off an epic upset, Comesana must attack the Rune serve and stretch those quad muscles.

Prediction: Holger Rune in straight sets.

Holger Rune vs Francisco Comesana Italian Open 2025 Betting Odds

Holger Rune Win: 2/7

Francisco Comesana Win: 3/1

ATP

ATP Masters 1000

Betting

Carlos Alcaraz

Francisco Comesana

Holger Rune

Italian Open

Rome Masters

Tennis

Sankalp Harikrishnan

A passionate sports fan through and through, I am currently pursuing my MA in Global Sports Journalism. I specialise in tennis and football writing at The Playoffs News, and I have prior experience working at EssentiallySports and Sportskeeda. Born and raised in Bengaluru, India, sport was my safe space right from my childhood. After trying my hand at multiple sports and representing my educational institutions in cricket, badminton and table tennis, I found sports media to be my calling.