Mandatory Credit: Geoff Burke-Imagn Images

Donna Vekic vs. Madison Keys Head-to-Head Record, Preview and Prediction for WTA Madrid Open 2025 Round of 16

Madison Keys and Donna Vekic set for another exciting clash at the Madrid Open 2025.

Mandatory Credit: Geoff Burke-Imagn Images

At the WTA Madrid Open 2025 in Spain, Donna Vekic will encounter Madison Keys in the round of 16. The fifth-seeded Keys and 19th-seeded Vekic both received byes in the first round. Moving on, Keys defeated Lucia Bronzetti in straight sets during the second round and then won a tightly contested match against Anna Kalinskaya in the third round. Vekic, meanwhile, claimed a straight-set victory over Hailey Baptiste before edging out Emma Navarro in a three-set battle in her third round.

Keys has been in exceptional form after winning her first Grand Slam title at the 2025 Australian Open, where she defeated Aryna Sabalenka in a thrilling final (6-3, 2-6, 7-5). She followed it up with a victory at the Adelaide International and has maintained a strong run in 2025 with improved consistency. In contrast, Vekic’s form has been inconsistent; she has faced more challenges this season, holding a 5–10 win-loss record and failing to advance past the round of 16 since Melbourne.

Catch her if you can 👊@Madison_Keys is through to the last 16 as she knocks out Kalinskaya in a tight straight sets match, 7-5, 7-6(3)!#MMOPEN pic.twitter.com/YZ8wVNuc1T
— wta (@WTA) April 26, 2025

Donna Vekic vs. Madison Keys Head-to-Head Record

Madison Keys leads the head-to-head against Donna Vekic with a record of 3-1. They had their first encounter at the 2016 French Open, where Keys defeated Vekic in straight sets in the round of 128.

Keys continued her dominance in 2018, overcoming Vekic in straight sets again in Rome. In 2019, however, Vekic ended Keys’ winning streak, securing a come-from-behind victory. However, at the 2025 Indian Wells round of 16, Keys regained the upper hand, winning in three sets.

Year	Event	Round	Winner	Score
2025	Indian Wells	Round of 16	Madison Keys	4-6, 7-6, 6-3
2019	Toronto	Round of 64	Donna Vekic	3-6, 7-5, 7-6
2018	Rome	Round of 32	Madison Keys	7-6, 7-5
2016	French Open	Round of 128	Madison Keys	6-3, 6-2

Donna Vekic vs. Madison Keys Comparison

Donna Vekic	Category	Madison Keys
21	WTA Ranking	5
379-288	Career W-L	404-223
5-10	YTD W-L	20-4
4	Career Titles	10
0	Grand Slams	1
0	YTD Titles	2

Donna Vekic vs. Madison Keys Prediction

Madison Keys is well-positioned to extend her head-to-head lead and improve her record with another victory, given her good form in 2025 and previous success versus Donna Vekic.

Prediction: Madison Keys in straight sets

Also Read: Stefanos Tsitsipas vs. Lorenzo Musetti Head-to-Head Record, Preview and Prediction for ATP Madrid Open 2025 Round of 16