Aug 29, 2024; Flushing, NY, USA; Carlos Alcaraz of Spain after winning a 2nd set game against Botic van De Zandschulp of the Netherlands on day four of the 2024 U.S. Open tennis tournament at USTA Billie Jean King National Tennis Center.

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Carlos Alcaraz vs. Reilly Opelka Preview, Prediction and Betting Odds for US Open 2025 Round-1

One of the most highly anticipated Round of 128 contests.

Looking to claim his seventh Grand Slam trophy, World No. 2 Carlos Alcaraz fires up his engine against home favourite Reilly Opelka in Round-1 of the 2025 US Open. While the Spaniard is aiming to become the top ranked player in the world by the end of these two weeks, his 6’11” counterpart will be determined to spoil the party and give his home fans something to cheer about. As two faithful servants of the men’s circuit square off, let us preview the encounter with the help of BetMGM.

Carlos Alcaraz vs Reilly Opelka Match Preview

Carlos Alcaraz has been seeded No. 2 in New York, just behind rival Jannik Sinner. The 22-year-old Spaniard enters the US Open on the back of a grand success at the 2025 Cincinnati Masters. With six trophies and two runner-up finishes to his name, ‘Carlitos’ has carved out an unimaginable 54-6 record. The former World No. 1 and five-time Grand Slam champion has reached seven straight tour-level finals before this event. On hard courts this year, Alcaraz has a 21-4 record with an 84% service game win rate.

100 – Carlos Alcaraz has converted 100 break points in Men's Singles Grand Slam events during 2025, the most of any player. Century.#USOpen | @atptour @usopen pic.twitter.com/fVNEBZULa1
— OptaAce (@OptaAce) August 21, 2025

Reilly Opelka is currently ranked No. 66 in the world, and is searching for his first title of 2025. He partnered American icon Venus Williams at the US Open Mixed Doubles Championship, but the pair fell short in Round-1. Opelka started his season with a win over Novak Djokovic en route to the final in Brisbane. He also reached the semis at the Libema Open – where he beat Daniil Medvedev. An impressive North American swing which included wins over the likes of Machac and de Minaur means that the 27-year-old has momentum going into this match.

The head-to-head record between Carlos Alcaraz and Reilly Opelka is 0-0, ahead of the 2025 US Open.

Carlos Alcaraz vs Reilly Opelka Career Comparison

Carlos Alcaraz	Category	Reilly Opelka
2	Current Ranking	66
263-62	Career W-L Record	119-109
54-6	YTD W-L Record	23-17
22	Career Titles	4
6	YTD Titles	0
5	Grand Slams	0

Carlos Alcaraz vs Reilly Opelka US Open 2025 Prediction

Taking into account the 22-year-old and his history with early hiccups in important tournaments, Opelka might have an opening or two. The American must extract as many free points on serve as possible, and then force Alcaraz into hitting a lot of second serves. If he can pounce on the Spaniard’s uncharacteristic dips in level and take the match deep with short rallies, Opelka stands a chance at wreaking havoc. However, Alcaraz is a master at weathering the storm.

Prediction: Carlos Alcaraz in four sets.

Carlos Alcaraz vs Reilly Opelka US Open 2025 Betting Odds

TBD.

(Image Credits: Robert Deutsch, Imagn Images)

ATP

Betting

Carlos Alcaraz

Reilly Opelka

Tennis

US Open

US Open 2025

Sankalp Harikrishnan

A passionate sports fan through and through, I am currently pursuing my MA in Global Sports Journalism. I specialise in tennis and football writing at The Playoffs News, and I have prior experience working at EssentiallySports and Sportskeeda. Born and raised in Bengaluru, India, sport was my safe space right from my childhood. After trying my hand at multiple sports and representing my educational institutions in cricket, badminton and table tennis, I found sports media to be my calling.