Mandatory Credit: Kirby Lee-Imagn Images

Buffalo Bills Favored To Win All 17 Regular Season Games in the 2025–26 NFL Season

Will this be the year the Bills go all the way?

Mandatory Credit: Kirby Lee-Imagn Images

As per the early betting odds in the NFL, the Buffalo Bills are the only team in the league that has opened as the favorites in all 17 of their regular season games for the upcoming 2025-26 NFL season. While it is still too early in the offseason to hold such notions in high regard, it does provide food for thought.

Last season, there was plenty of uncertainty surrounding the Bills after they went through an offseason in which they lost their primary two wide receivers in Stefon Diggs and Gabe Davis. On defense, Buffalo also lost the likes of cornerback Tre’Davious White and safety Jordan Poyer in free agency.

With no real idea of how the Bills would function, especially offensively, it was rather surprising to see Buffalo win their division yet again. Quarterback Josh Allen led from the front, earning him the first NFL MVP of his career as the Bills made it all the way to the AFC Championship game. But what is it that has Buffalo as the favorite to win each of its games this season?

What Makes the Bills the Favorite Across All Regular Season Games?

Following the release of the 2025-26 NFL schedule, the point spreads for all regular season games were also released, and the one stat that popped out was that the Bills are favored to win all 17 of their games. There are multiple reasons as to why this is the case, so let us take a look at what they are.

The Bills are the only team in the NFL favored in every game 😳

(via @DKSportsbook) pic.twitter.com/GrmZ7yyfrH
— br_betting (@br_betting) May 15, 2025

Talented and Balanced Roster

The Bills will enter the 2025-26 season with talent across the roster on both sides of the ball. Josh Allen will lead from the front once again, and he will be extra motivated following his MVP performance from last season.

Add to that an offensive line that allowed the fewest sacks of all teams last season. The importance of this cannot be understated, as it helps in both the run game as well as the passing game. James Cook had a 1,000-yard season in 2024, and he should be able to continue his fine performances this year as well.

The receiving core is also looking good, with Khalil Shakir leading the charge and stepping up last year, leading the way for rookie wideout Keon Coleman. If Coleman and tight end Dalton Kincaid can improve their production, the Bills have plenty of firepower to work with.

Defensively, the addition of Joey Bosa could be instrumental if he can regain his form from his earlier days with the Chargers. Along with Bosa, Greg Rousseau, and Ed Oliver all have the potential to cause problems up front, while linebackers Terrel Bernard and Matt Milano can provide substantial support from the second level of defense.

Easy Strength of Schedule

The Bills will enter this season with one of the easiest strength-of-schedules (.479) among the 32 teams. The Bills are tied with the Jacksonville Jaguars at the 23rd spot, with only 9 other teams having an easier schedule this year.

Buffalo’s schedule includes 6 games against their divisional rivals, the Jets, Patriots, and Dolphins, none of whom are exactly hot on their trail. They also play the NFC South this year, arguably the weakest division in the conference, against the Panthers, Saints, and the Buccaneers.

𝐎𝐔𝐑 𝟐𝟎𝟐𝟓 𝐒𝐂𝐇𝐄𝐃𝐔𝐋𝐄 𝐈𝐒 𝐇𝐄𝐑𝐄‼️https://t.co/v8vL05zdhf | #BillsMafia pic.twitter.com/F77HDrBOlt
— Buffalo Bills (@BuffaloBills) May 15, 2025

Home Games Against Toughest Rivals

While the Bills have a few tough games against teams such as the Chiefs, Ravens, and Eagles, two of these games will be at home. Their week 1 game against Baltimore is a prime time SNF game at Highmark Stadium, and although it could be a difficult season opener, the Bills Mafia could really get behind their team in this battle of the big guns.

Moving on, Buffalo will also take on last year’s Super Bowl finalist, the Kansas City Chiefs at home in week 9, where the Bills will have a key advantage. Following a week 7 bye week and a game against the Panthers in week 8, they will take on a Chiefs team coming off a short week, as KC will be playing the Commanders on MNF the week prior.

Also Read: When Does NFL Training Camp Start? NFL Training Camp 2025 Start Date, Locations and More

As a result of various factors, Buffalo has rightly been named the favorite in all of their matches as of now. But, it is important to note that much can change in the NFL with the blink of an eye.

Buffalo Bills

Josh Allen

NFL

Devavrat Kulkarni

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I am a content writer for the NFL team, and joined The Playoffs after working with Sportskeeda and NFL Analysis as an NFL writer. After starting my professional career as a French-to-English translator, working as a content writer is a new adventure for me. I started out in the sports media field for two main reasons: my love for sports in general, especially the NFL, NBA, and Tennis, as well as my passion for writing. The best part of this job is that I get to write a variety of pieces with the freedom to explore content from various angles. It also enables me to stay up to date with the sporting world, which otherwise can be difficult to do in the day-to-day grind. In a world full of chaos, sports unite and entertain like nothing else!