Indianapolis Colts vs Atlanta Falcons Predictions, Odds, and Best Bets for Week 10 NFL 2025-26 Season

The Indianapolis Colts will face the Atlanta Falcons for their Week 10 matchup, live from Olympic Stadium Berlin in Berlin, Germany, for an international matchup. The Colts have been one of the best teams in the NFL and are 7-2 for the season, but are coming off a recent loss to the Pittsburgh Steelers in Week 9. While their QB1 Daniel Jones has been terrific this season, he threw 3 interceptions last game and only 1 TD on 50 attempts, indicating a middle of the season slump. Similarly, Jonathan Taylor is coming off his worst game , putting up only 45 yards on no TDs. The Colts are still leading the AFC South and are one of the best teams in the NFL, despite their two losses.

View this post on Instagram

A post shared by Blue (@bluecoltsmascot)

The Atlanta Falcons are 3-5 for the season and nothing has been going right for them recently. After an impressive win against the Buffalo Bills in Week 5, they have lost 3 straight games to the 49ers, Dolphins, and Patriots. They are coming off a recent loss to the Patriots, in a very close game, despite Michael Penix Jr. putting up 3 TDs. Something needs to change for Atlanta, as they are two games below .500 and could miss out on the playoffs as Week 10 is already here.

Recommended Bets and Updated Odds

Recommended Bets	Fanduel	BetMGM
Jonathan Taylor anytime TD	-330	-325
Michael Penix Jr. Over 225.5 passing yards	-114	-115
Daniel Jones under 32.5 passing attempts	-146	-130

FanDuel

High total bonus ceiling

Daily second-chance bet protection

No promo code required

$150

Welcome offer

Bet $5 & Get $150 in Bonus Bets

Click to reveal code

COPIED

F A N D U V I P

Claim now

New customers only. Must be 21+ in most jurisdictions, but 18+ in DC, KY, and WY. Offer is valid only in eligible regulated states/jurisdictions and not available in AR; void where prohibited. First online real-money wager only; cashed-out or bonus-funded bets are excluded.

Analysis and Rationale

Jonathan Taylor is threat to score at any given moment, looking at the fact that Taylor is leading the league in rushing TDs with 12 and has scored at least one touchdown in the last 4/5 games. The Falcons’ rushing defense has also taken a huge hit, sitting at 23rd in the league and we expect Taylor to have a tremendous game.

Michael Penix Jr. should be able to get over 225.5 passing yards as he’s had games over this threshold for 4 of 7 games so far. He’s also had 4 games over 200+ passing yards in the last four games. Looking at the Colts’ terrible pass defense, ranking 26th, Penix Jr. should be able to cross 225.5 passing yards, especially if the game gets close.

Daniel Jones should remain under 32.5 passing attempts as he’s coming off a 50 passing attempts game, where he threw 3 interceptions against the Steelers. Jones has only 4 games where he’s gone beyond 32.5 passing attempts, and looking at the Falcons’ stout passing defense, ranking 1st, we expect the Colts to run the football more than pass.

Colts vs Falcons Prediction

We expect the Colts to walk away with a victory because of the Falcons‘ 3-game losing streak and the Colts’ unstoppable rushing game, led by Jonathan Taylor. While the Falcons may contain Daniel Jones and his passing game, according to the stats and the ratings, Atlanta may not have an answer for Taylor, who’s leading the league in TDs and rush yards.

Prediction: Colts win the game 28-21

View this post on Instagram

A post shared by NFL Deutschland (@nfldeutschland)

Week 10 Colts vs Falcons Spread and Betting Odds

Looking at the spread and the moneyline, the Colts are the favorites to walk away with a victory over the Falcons, as per BetMGM

Teams	Spread	Total Points	Moneyline
Falcons	+6.5 (-110)	48.5 (-110)	+240
Colts	-6.5 (-110)	48.5 (-110)	-295

BetMGM

All in one gambling website

Reputable gambling name

Multiple betting features including live streaming

$1,500

Welcome offer

Get up to $1,500 Back in Bonus Bets

Click to copy code

COPIED

TPOVIP

Claim now

21+. AZ/CO/IL/IN/IA/KS/LA/MD/MA/MI/NJ/OH/PA/TN/ VA/WV/WY only. Offer not available in DC/MS/NV/NY/PR. New customers only. Qualifying deposit (min $10) and first real money wager required. If qualifying bet settles as a loss, user is refunded 100% in non-withdrawable bonus bets up to $1,500. Full T&Cs can be found on betmgm.com.

If you’re looking for a complete guide to the best NFL betting sites, we’ve got you covered.

Colts vs Falcons Best Bets

Here are some of the best player bets and over/under for the Indianapolis Colts and the Atlanta Falcons, as per BetMGM.

Indianapolis Colts Over/Under Odds

Listed below are some of the over/under odds for the Indianapolis Colts, as per BetMGM

Over/Under Bets	Over	Under
Daniel Jones passing yards	246.5 (-115)	246.5 (-115)
Jonathan Taylor rushing yards	93.5 (-115)	93.5 (-115)
Michael Pittman Jr. receiving yards	55.5 (-115)	55.5 (-115)

Indianapolis Colts Best Player Bets

Here are some of the best player bets for the Indianapolis Colts as per BetMGM

Jonathan Taylor anytime TD scorer: -325
Daniel Jones to have over 250+ passing yards: +100
Daniel Jones to have over 1.5 passing TDs: -125

Atlanta Falcons Over/Under Odds

Listed below are over/under odds for the Atlanta Falcons, as per BetMGM

Over/Under Bets	Over	Under
Drake London receiving yards	71.5 (-115)	71.5 (-115)
Bijan Robinson rushing yards	68.5 (-115)	68.5 (-115)
Michael Penix Jr. passing yards	225.5 (-115)	225.5 (-115)

Atlanta Falcons Best Player Bets

Here are some of the best player bets for the Atlanta Falcons, as per BetMGM

Michael Penix Jr. under 1.5 passing TD: -160
Bijan Robinson anytime TD scorer: -140
Drake London anytime TD scorer: +145

BetMGM

All in one gambling website

Reputable gambling name

Multiple betting features including live streaming

$1,500

Welcome offer

Get up to $1,500 Back in Bonus Bets

Click to copy code

COPIED

TPOVIP

Claim now

(According to BetMGM: BetMGM offers exclusive promo codes, bonus deals and accurate odds for users upon signing up. Use BetMGM to ace your betting game in all sports!)

FAQs

Who is favored to win between the Colts vs Falcons?
The Colts are 6.5-point favorites to win the matchup against Falcons.

What is the over/under total for the game?
The over/under for total points is set at 48.5

What is the predicted score for the Colts vs Falcons game?
We expect the Colts to take down the Falcons in a close battle, and the Final score to be 28-21.

Eric Divakaran

nba

nfl

mma

I cover the National Football League and things cannot get better than that. I always dreamed to play football or basketball professionally since I’m built like a Running Back. But now that I can’t, since I’m technically in the “Unc” age, I thought why not pick a career in sports industry? So here I am, doing what I love, and hoping that the Commanders win the Super Bowl. I give love to players when it’s due, but can be critical about their performances at the same time. Enough about me, now let my articles do all the talking.