Mandatory Credit: Geoff Burke-Imagn Images

Novak Djokovic/Olga Danilovic vs. Mirra Andreeva/Daniil Medvedev Preview, Prediction and Betting Odds for US Open 2025 Mixed Doubles Round – 1

Djokovic and Danilovic take on Andreeva and Medvedev in the US Open mixed doubles first round.

Mandatory Credit: Geoff Burke-Imagn Images

The 2025 US Open mixed doubles first round features Novak Djokovic and Olga Danilovic against Mirra Andreeva and Daniil Medvedev. It’s an intriguing matchup of proven champions and rising stars. Djokovic and Danilovic bring Serbian experience and recent form, while Andreeva and Medvedev combine energy with tactical unpredictability, setting the stage for a competitive opening-round match.

Joining forces and taking the Mixed Doubles stage, Novak Djokovic and Olga Danilovic are partnering up in the Big Apple!https://t.co/lokEel4tKQ
— US Open Tennis (@usopen) August 16, 2025

Novak Djokovic/Olga Danilovic vs. Mirra Andreeva/Daniil Medvedev Preview

Djokovic continues to add new chapters to a remarkable career. At 38, he remains focused on singles but enters the mixed doubles draw with Olga Danilovic. Djokovic’s season already includes a 100th singles title in Geneva and a milestone 100 Wimbledon main-draw wins, underlining his consistency and resilience. Danilovic, who recently reached a career-high No. 32 and collected a WTA 125 trophy in Antalya, brings her left-handed power and steady improvement. Their partnership has the blend of experience and momentum.

Novak Djokovic’s first practice in New York.

He’s ready. 💪🏻pic.twitter.com/HRa6B25JVg
— Danny (@DjokovicFan_) August 19, 2025

Across the net, Andreeva has quickly become one of the most talked-about young players on tour. Still a teenager, she has climbed into the WTA top five this season, winning titles in Dubai and Indian Wells and a doubles title in Miami with Diana Shnaider. Her all-court game has already translated to big-stage success, including an Olympic silver medal last year.

Medvedev, known as a hard-court specialist, joins her after a season of mixed results highlighted by a Halle final and an Indian Wells semifinal. Though not always predictable, his ability to raise his level against top names makes this pairing especially interesting.

On the same page!

Daniil Medvedev and Mirra Andreeva have entered the US Open Mixed Doubles Championships and are already seeing eye-to-eye 👀 pic.twitter.com/hYfSowtObm
— US Open Tennis (@usopen) July 11, 2025

Novak Djokovic/Olga Danilovic vs. Mirra Andreeva/Daniil Medvedev Head-to-Head Record

Novak Djokovic/Olga Danilovic and Mirra Andreeva/Daniil Medvedev do not have a head-to-head record yet.

Novak Djokovic/Olga Danilovic vs. Mirra Andreeva/Daniil Medvedev Career Comparison

Djokovic/Danilovic	Category	Andreeva/Medvedev
0 / 0	Doubles Grand Slams	0 / 0
100 / 2	WTA Singles Titles	3 / 20
1 / 2	WTA Doubles Titles	2 / 0
No. 490 / No. 97	Current Doubles Ranking	No. 13 / –
No. 114 / No. 97	Career-Best Doubles Ranking	No. 14 / No. 170

Novak Djokovic/Olga Danilovic vs. Mirra Andreeva/Daniil Medvedev US Open 2025 Prediction

Andreeva and Medvedev may be underdogs, but the storyline is compelling. Andreeva is already proven on big stages and is paired with Medvedev’s unpredictability. If they find cohesion early, this partnership has the potential to unsettle the Djokovic/Danilovic rhythm. But the latter duo is the favorite, and if they falter, then only Andreeva and Medvedev have a chance.

Novak Djokovic did the "Pump It Up" dance with his son after his Wimbledon quarterfinal win ❤️🕺 pic.twitter.com/CVDq8c8fnZ
— SportsCenter (@SportsCenter) July 9, 2025

Prediction: Novak Djokovic/Olga Danilovic in straight sets.

Novak Djokovic/Olga Danilovic vs. Mirra Andreeva/Daniil Medvedev US Open 2025 Betting Odds

With Djokovic and Danilovic slight favorites at 8/11, the Serbian pair are backed to edge through on the strength of Djokovic’s big-match experience and Danilovic’s recent form.

Here are the betting odds for Novak Djokovic/Olga Danilovic vs. Mirra Andreeva/Daniil Medvedev as per betting markets:

Novak Djokovic/Olga Danilovic: 8/11

Mirra Andreeva/Daniil Medvedev: 11/10

Mandatory Image Credit: Geoff Burke-Imagn Images

Mirra Andreeva

Novak Djokovic

Olga Danilovic

US Open 2025

Rudra Dubey

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I’m an academic turned sports writer from Raipur, India, specializing in the NFL, MMA, and tennis at The Playoffs. I previously wrote for Sportskeeda and hold a B.A. and M.A. in History. My journey into sports media began far from the field, rooted in the arts and sciences. Funny enough, I didn’t grow up a sports fan; I used to see it all as just noise. But a fateful writing job introduced me to the world of sports, and what began as a gig quickly became a passion. I understood those voices aren’t noise; they’re emotions of true sports fans, and now I am one of them, writing with the same energy I once questioned.