One of the most anticipated matches of the international break sees Argentina take on Uruguay in a high-voltage clash on March 21.
The road to the 2026 FIFA World Cup continues on March 21 as teams battle for crucial points in the World Cup Qualifiers. With only a limited number of spots available for the prestigious tournament, every match carries is of significant importance. Among the standout fixtures of the day, England begin their campaign under new manager Thomas Tuchel, facing Albania at Wembley in a match.
Meanwhile, one of the most anticipated matches of the international break sees Argentina take on Uruguay in a high-voltage clash in the CONMEBOL World Cup qualifiers. The reigning world champions will face a stiff challenge from Marcelo Bielsa’s Uruguay, who sit in second place, five points behind Argentina in the table. Uruguay have already proven their ability to beat the world champions, having defeated Argentina earlier in the qualifying campaign. With a passionate crowd at the Estadio Centenario, the Uruguayans will be eager to get a good result on home turf.
Let’s take a look at all fixtures on March 21:
| Matches | Date | Time (ET) |
| Ecuador vs Venezuela | March 21 | 5:00 PM |
| Uruguay vs Argentina | March 21 | 7:30 PM |
| Matches | Date | Time (ET) |
| Cyprus vs San Marino | March 21 | 1:00 PM |
| England vs Albania | March 21 | 3:45 PM |
| Poland vs Lithuania | March 21 | 3:45 PM |
| Andorra vs Latvia | March 21 | 3:45 PM |
| Malta vs Finland | March 21 | 3:45 PM |
| Romania vs Bosnia-Herzegovina | March 21 | 3:45 PM |
African nations are playing group stage matches for the World Cup qualifying. Here are the matches on March 21:
| Matches | Date | Time (ET) |
| Botswana vs Algeria | March 21 | 9:00 AM |
| Rwanda vs Nigeria | March 21 | 12:00 PM |
| South Africa vs Lesotho | March 21 | 12:00 PM |
| Ghana vs Chad | March 21 | 3:00 PM |
| Burundi vs Ivory Coast | March 21 | 3:00 PM |
| Ethiopia vs Egypt | March 21 | 5:00 PM |
| Niger vs Morocco | March 21 | 5:30 PM |
| Matches | Date | Time (ET) |
| New Zealand vs Fiji | March 21 | 2:00 AM |
| Matches | Date | Time (ET) |
| Northern Ireland vs Switzerland | March 21 | 3:45 PM |
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