Cardinals vs Seahawks Same Game Parlays and Underdog Bets for Week 4 Thursday Night Football Tonight

Week 4 of the NFL season kicks off with the Arizona Cardinals taking on their divisional opponents, the Seattle Seahawks, at State Farm Stadium in Glendale, Arizona. Both teams are entering the game with a 2-1 record, with the opportunity to build on a strong start to their respective seasons.

The Cardinals’ last game was a close 15-16 loss to another division opponent, the San Francisco 49ers. The Seahawks, however, pulled off a huge 44-13 win over the New Orleans Saints.

TNF Cardinals vs Seahawks Same Game Parlays

Here are some same-game parlays for the Arizona Cardinals vs Seattle Seahawks game tonight on Thursday Night Football, according to FanDuel.

Same Game Parlay 1

Jaxson Smith-Njigba Anytime Touchdown Scorer (+160) + Trey McBride Anytime Touchdown Scorer (+165) + Sam Darnold 225+ Yards (-122)

Parlay Payout: Bet $100 to win $777.59

Jaxson Smith-Njigba is the go-to receiver for Sam Darnold on the Seahawks as the offense runs through him following DK Metcalf’s departure. He also had his first receiving touchdown of the season last week against the Saints.

Trey McBride is the leading pass-catcher for the Cardinals through 3 games and also snagged a touchdown in last week’s loss against the 49ers.

Despite a slow start to the season in the first game, the Seahawks’ quarterback, Sam Darnold, has thrown for over 200 yards in his last two outings. There is a good chance this streak continues into week 4.

been waiting to wear these pic.twitter.com/ZXwi2XDWax
— Arizona Cardinals (@AZCardinals) September 24, 2025

Same Game Parlay 2

Sam Darnold 2+ passing touchdowns (+152) + Kenneth Walker III 60+ Yards (+126) + Trey Benson 70+ Yards (+152)

Parlay Payout: Bet $100 to win $1,413.97

Sam Darnold’s 2+ passing touchdowns seems like a good bet, considering he has thrown 2 in each of the previous couple of games. Darnold and his pass catchers are having better chemistry 3 games into the season, and it should continue tonight against the Cardinals.

Kenneth Walker III could have a bigger impact in tonight’s game as Zach Charbonnet is listed as questionable due to a foot injury. Even if Charbonnet does play, Walker should be getting more carries in the backfield.

With James Conner out for the season, most of the responsibility in the backfield now falls on Trey Benson. Conner and Benson had shared the workload up until now, but that will change following the former’s injury.

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Same Game Parlay 3

Trey McBride 60+ receiving yards (-146) + Jaxon Smith-Njigba 100+ Yards (+152) + Cooper Kupp 5+ Receptions (+146)

Parlay Payout: Bet $100 to win $809.28

Tight end Trey McBride has been the most targeted pass-catcher so far by Kyler Murray. He has eclipsed 60 receiving yards twice already this season, making this bet worth considering.

Jaxson Smith-Njigba has grown in his role as the leading receiver and will remain Darnold’s number one target. Smith-Njigba has 100+ receiving yards in 2 of the 3 games this season, while he also had 96 yards receiving in the third game. It wouldn’t be a surprise if he goes over 100 yards once again in today’s game.

Cooper Kupp has gotten off to a slow start with only one game above 5 receptions so far. However, being a divisional game, Smith-Njigba could be marked closely by the Cardinals’ defense, allowing Kupp more targets.

Coming to a stadium near you. 🍿 pic.twitter.com/ZxA91Qjf7z
— Seattle Seahawks (@Seahawks) September 22, 2025

Cardinals vs Seahawks Underdog Bets

Here are some of the best underdog bets for the Arizona Cardinals vs Seattle Seahawks game. (sourced from FanDuel).

Underdog Bets	Odds
Marvin Harrison Jr. 60+ receiving yards	+154
Trey Benson anytime touchdown scorer	+110
Arizona Cardinals to win	+108

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Marvin Harrison Jr. has averaged just below 50 receiving yards in his two games against the Seahawks last season. Now that he is in year 2, his development has progressed. As WR1, Harrison has a good chance to record 60 or more receiving yards in tonight’s game.

Trey Benson will have the primary rushing duties with James Conner’s season ending injury, making Benson’s anytime touchdown a good probability.

The Cardinals vs Seahawks is a divisional game, but Arizona will have the home support. Both teams are 2-1, but if the Cardinals’ offense can get going, the defense has been playing well enough to stop Seattle.

The above odds are sourced from FanDuel. Use FanDuel to ace your betting game in all sports!

Mandatory Credit: Steven Bisig-Imagn Images

Devavrat Kulkarni

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I am a content writer for the NFL team, and joined The Playoffs after working with Sportskeeda and NFL Analysis as an NFL writer. After starting my professional career as a French-to-English translator, working as a content writer is a new adventure for me. I started out in the sports media field for two main reasons: my love for sports in general, especially the NFL, NBA, and Tennis, as well as my passion for writing. The best part of this job is that I get to write a variety of pieces with the freedom to explore content from various angles. It also enables me to stay up to date with the sporting world, which otherwise can be difficult to do in the day-to-day grind. In a world full of chaos, sports unite and entertain like nothing else!