Tennessee Titans vs Indianapolis Colts Preview, Betting Odds, and Predictions – NFL 2025-26 Season Week 3

Tennessee Titans vs Indianapolis Colts Preview, Betting Odds, and Predictions – NFL 2025-26 Season Week 3

The Indianapolis Colts are travelling on the road to take on the Tennessee Titans for this Week 3 NFL action. The Colts are currently leading the AFC South with back-to-back wins in Weeks 1 and 2, and are trying to extend their streak to 3. Meanwhile, the titans are struggling to find a footing in the 2025 season, losing 2 straight games, even though we have seen flashes for superstar potential from their rookie QB Cam Ward.

FanDuel

High total bonus ceiling

Daily second-chance bet protection

No promo code required

$150

Welcome offer

Bet $5 & Get $150 in Bonus Bets

Click to reveal code

COPIED

F A N D U V I P

Claim now

New customers only. Must be 21+ in most jurisdictions, but 18+ in DC, KY, and WY. Offer is valid only in eligible regulated states/jurisdictions and not available in AR; void where prohibited. First online real-money wager only; cashed-out or bonus-funded bets are excluded.

Analysis and Rationale

Tony Pollard has just 29 receiving yards on 2 targets through two games, averaging 14.5 YPG, well under what is usually expected of him. While Tennessee is trying to move on run-heavy to pass-heavy offense, the transition is still going to take some time, giving that their No.1 overall pick has only played two NFL games thus far. Therefore, Pollard’s bet is a safe pick.

Cam Ward has 18 rushing yards on 7 carries through two games, but faces a Colts defense allowing just 83 rushing yards per game. Looking at this, we believe that Ward will not get many chances to rush with the ball, and will instead have to find his receivers more. Look out for Ward to have high passing attempts this game, instead of him using his feet to secure first downs or TDs.

For Daniel Jones over 30.5 passing attempts, Jones had 29 attempts in Week 1 and 34 in Week 2, averaging 31.5. The Colts’ balanced offense paired with the Titans’ weak pass defense suggest a high-passing game plan.

Tennessee Titans vs Indianapolis Colts Preview

In Week 3’s AFC South clash at Nissan Stadium, the surging 2-0 Colts, led by Daniel Jones’ efficient 588 passing yards and Jonathan Taylor’s ground attack, faces the winless Titans led by their rookie QB. Cam Ward has shown flashes but Tennessee’s offense ranks amongst the bottom feeders, plagued by penalties and lack of deep threats. Meanwhile, Colts’ explosive attack has been hard to keep up with, as we saw in Week 1 and 2, turning this game into a potential blowout win for the Colts.

Tennessee Titans Best Bets – Over/Under and Player Bets

Here are over/under and best player bets for the Tennessee Titans, according to BetMGM

Tennessee Titans Best Player Bets

Below are some of the best player bets for the Tennessee Titans, according to BetMGM

• Calvin Ridley to have Under 4.5 receptions made: -155
• Cam Ward Under 1.5 TDs: -190
• Tony Pollard Anytime TD scorer: -115

BetMGM

All in one gambling website

Reputable gambling name

Multiple betting features including live streaming

$1,500

Welcome offer

Get up to $1,500 Back in Bonus Bets

Click to copy code

COPIED

TPOVIP

Claim now

21+. AZ/CO/IL/IN/IA/KS/LA/MD/MA/MI/NJ/OH/PA/TN/ VA/WV/WY only. Offer not available in DC/MS/NV/NY/PR. New customers only. Qualifying deposit (min $10) and first real money wager required. If qualifying bet settles as a loss, user is refunded 100% in non-withdrawable bonus bets up to $1,500. Full T&Cs can be found on betmgm.com.

Indianapolis Colts Best Bets – Over/Under and Player Bets

Here are over/under and best player bets for the Indianapolis Colts, according to BetMGM

Indianapolis Colts Best Player Bets

Below are some of the best player bets for the Indianapolis Colts, according to BetMGM

• Tyler Warren Over 4.5 Receptions made: +115
• Daniel Jones Under 20.5 Pass completions: -130
• Jonathan Taylor Under 21.5 Rushing attempts: -130

Tennessee Titans vs Indianapolis Colts Prediction for Week 3 of the 2025-26 NFL Season

In Week 3’s AFC South matchup, the 2-0 Colts, powered by Daniel Jones’ efficient passing and Jonathan Taylor’s ground dominance, should be able to invade a desperate 0-2 Titans squad. While we do expect the Titans to put up a fight, the Colts are on a roll and are looking like one of the best teams in this season. The Titans’ O-line along with weak pass defense, may not be able to stop the Colts.

Prediction: Colts win the game with a final score of 27-17

Titans vs Colts Spread and Betting Odds

The spread and the moneyline show that the Colts are the clear favorites to win this matchup against the Titans, according to BetMGM

BetMGM

All in one gambling website

Reputable gambling name

Multiple betting features including live streaming

$1,500

Welcome offer

Get up to $1,500 Back in Bonus Bets

Click to copy code

COPIED

TPOVIP

Claim now

21+. AZ/CO/IL/IN/IA/KS/LA/MD/MA/MI/NJ/OH/PA/TN/ VA/WV/WY only. Offer not available in DC/MS/NV/NY/PR. New customers only. Qualifying deposit (min $10) and first real money wager required. If qualifying bet settles as a loss, user is refunded 100% in non-withdrawable bonus bets up to $1,500. Full T&Cs can be found on betmgm.com.

(According to BetMGM: BetMGM offers exclusive promo codes, bonus deals and accurate odds for users upon signing up. Use BetMGM to ace your betting game in all sports!)

FAQs

Who is favored to win the Titans vs Colts game?
The Indianapolis Colts are 4-point favorties with a -210 moneyline.

What is the over/under total for the game?
The Total points line is set a 43.5.

What is the predicted final score?
Colts win 27-17 over the Titans.

You May Also Read

NFL

March 30, 2026

NFL 2026-27 Season – Which Conference is the Favorite to Win Super Bowl LXI?

Read more

NFL

March 27, 2026

2026 NFL Draft – Who is the Favorite to Get Drafted at No. 5 Overall?

Read more

NFL

March 27, 2026

2026 NFL Draft – Who is the Favorite to Get drafted at No. 4 Overall?

Read more

NFL

March 24, 2026

2026 NFL Draft – Who is the Favorite to get Drafted at No. 3 Overall?

Read more

NFL

March 24, 2026

2026 NFL Draft – Who is the Favorite to get drafted at No. 2 Overall?

Read more

NFL

March 23, 2026

2026 NFL Draft – Who is the Favorite to get Drafted at No.1 Overall?

Read more

NFL

March 22, 2026

NFL 2026-27 AFC Conference Winner Odds – Where Each Team Stands Entering the 2026-27 Season

Read more

NFL

March 21, 2026

NFL 2026-27 NFC Conference Winner Odds – Where Each Team Stands Entering the 2026-27 Season

Read more

Eric Divakaran

nba

nfl

mma

I cover the National Football League and things cannot get better than that. I always dreamed to play football or basketball professionally since I’m built like a Running Back. But now that I can’t, since I’m technically in the “Unc” age, I thought why not pick a career in sports industry? So here I am, doing what I love, and hoping that the Commanders win the Super Bowl. I give love to players when it’s due, but can be critical about their performances at the same time. Enough about me, now let my articles do all the talking. 

Read more

NFL 2026–27 Arizona Cardinals Regular Season Over/Under Odds for Total Wins – Best Early Odds and Predictions for 2026–27 NFL Season

Eric Divakaran

NFL 2026–27 Tennessee Titans Regular Season Over/under Odds for Total Wins – Best Early Odds and Predictions for 2026–27 NFL Season

Devavrat Kulkarni

NFL 2026-27 AFC Conference Winner Odds – Where Each Team Stands Entering the 2026-27 Season

Eric Divakaran

NFL 2026/27 Defensive Player Of the Year Award Odds – Who are the Early Favorites to Take Home the DPOY Honors?

Eric Divakaran