San Francisco 49ers vs. Seattle Seahawks predictions, odds, and top picks – November 17, 2024

The San Francisco 49ers (5-4) host the Seattle Seahawks (4-5) at Levi’s Stadium in Santa Clara, California, on Sunday, November 17, 2024. Kickoff is scheduled for 4:05 p.m. ET, with live coverage on FOX and streaming available on FOX Sports.

Both teams are vying for a crucial NFC West victory, but San Francisco holds the upper hand as 6.5-point favorites. With the over/under set at 48 points, this matchup could feature an exciting mix of offensive fireworks and defensive plays.

San Francisco 49ers vs. Seattle Seahawks betting odds

• Spread: 49ers -6.5
• Favorite Spread Odds: -112
• Underdog Spread Odds: -108
• Total Points: 48
• Over Total Odds: -110
• Under Total Odds: -110

Where to watch San Francisco 49ers vs. Seattle Seahawks?

You can catch the 49ers vs. Seahawks live on FOX, with streaming available on FOX Sports.

• Game Date: Sunday, November 17, 2024
• Time: 4:05 p.m. ET
• Venue: Levi’s Stadium, Santa Clara, California
• Broadcast: FOX
• Live Updates: FOX Sports

San Francisco 49ers vs. Seattle Seahawks prediction

This divisional rivalry is expected to tilt in favor of the 49ers. Here are three key bets for the game:

1. Bet 1 – 49ers to Cover (-6.5):
   The 49ers have dominated the Seahawks in recent years, winning their last five matchups by an average margin of 13.6 points. Expect San Francisco to control the game on both sides of the ball and cover the spread.
2. Bet 2 – Total Points: Over 48 (-110):
   With both teams exceeding the point total in more than half their games this season, the over is a strong choice. The Seahawks’ passing attack and the 49ers’ balanced offense set the stage for a high-scoring affair.
3. Bet 3 – 49ers Moneyline (-260):
   San Francisco’s superior roster depth, led by Brock Purdy and George Kittle, makes them heavy favorites. Their 74.9% implied win probability reflects their dominance in recent matchups.

San Francisco 49ers vs. Seattle Seahawks preview

San Francisco 49ers: Recent performance

The 49ers are riding a wave of confidence after five consecutive wins over Seattle. Their balanced attack, led by quarterback Brock Purdy, ranks second in passing yards per game (262.8) and fourth in rushing yards (149.7). Defensively, Nick Bosa and Fred Warner anchor a unit that has held opponents to 22.4 points per game, ranking 17th in the league.

Seattle Seahawks: Recent performance

The Seahawks have struggled against San Francisco, being outscored by 68 points in their last five meetings. Geno Smith leads the NFL in passing yards (268.2 per game), but Seattle’s 27th-ranked rushing attack (91.2 yards per game) limits their offensive balance. Defensively, their 26th-ranked rush defense could face significant challenges against the 49ers’ ground game.

San Francisco 49ers vs. Seattle Seahawks – Key points

Who’s expected to win?

The 49ers are the clear favorites, with a superior offense and recent dominance over the Seahawks. Their 74.9% implied win probability reflects the confidence bettors and analysts have in their ability to secure another divisional win.

Which team has more wins?

The 49ers hold a slight edge at 5-4 compared to the Seahawks’ 4-5 record. San Francisco has consistently outperformed Seattle in their recent matchups, making them the team to beat in this game.

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