Sep 10, 2023; Flushing, NY, USA; Novak Djokovic of Serbia celebrates with the championship trophy after his match against Daniil Medvedev (not pictured) in the men's singles final on day fourteen of the 2023 U.S. Open tennis tournament at USTA Billie Jean King National Tennis Center.

tennis

Novak Djokovic Draw Analysis and Odds – What Are Djokovic’s Odds to Win the US Open 2025?

The Serb is chasing a record-shattering 25th major.

Former World No. 1 Novak Djokovic is set to hunt down the playing field in his quest for the elusive 25th Grand Slam title at the 2025 US Open. With the tournament beginning on August 24 and the draw getting confirmed, the Serbian icon has been informed of his path to the record-breaking crown. While Djokovic has some initial tests to overcome, his real challenges will start in the second week.

Having won the titles at Flushing Meadows on four previous occasions (2011, 2015, 2018, 2023), the seventh seed is always a contender for the men’s championship. Last year, Djokovic was dumped out of the tournament in Round-3 by Australian sensation Alexei Popyrin. As a result, the 2025 edition of the competition presents a perfect opportunity for ‘Nole’ to silence his critics.

Here is the draw analysis and pre-tournament odds for 24-time Grand Slam champion Novak Djokovic:

Novak Djokovic Draw Analysis

🇷🇸🇺🇸 Novak Djokovic’s 2025 US Open draw:

R1 – Tien
R2 – Q/LL
R3 – Michelsen
R4 – Rune/Tiafoe
QF – Fritz/Mensik/Machac
SF – Alcaraz/Shelton/Ruud
F – Sinner/Zverev/Draper/de Minaur

📸 Matt Rourke/AP pic.twitter.com/y9YU3TGD8X
— Olly Tennis 🎾🇬🇧 (@Olly_Tennis_) August 21, 2025

Djokovic is the No. 7 seed at the 2025 US Open. Placed in the same quarter as fourth seed and reigning finalist Taylor Fritz, the Serb has a bittersweet path to the final. He will begin his campaign against American southpaw Learner Tien, who is making waves on tour at the moment. It will be the first career meeting between the two stars. To round off the first week, Djokovic could face a qualifier in Round-2, and one of the home favourites in the form of Alex Michelsen or Sebastian Korda in Round-3.

Provided the Djoker makes it through to the second week, a mouth-watering clash against either No. 11 seed Holger Rune or two-time USO semifinalist Frances Tiafoe is on the cards. This will be an interesting challenge for the Serbian, particularly against the American who thrives on night session conditions in New York. While powerhouse American Taylor Fritz is slated to be his quarterfinal opponent, don’t sleep on Czechia’s youngest prodigy Jakub Mensik. The 19-year-old has a phenomenal hard court game, and already defeated Djokovic in the Miami Open final earlier this year.

80 – Novak Djokovic will become the third player to make 80+ appearances in Men's Singles Grand Slams during the Open Era. Longevity. #USOpen | @atptour @usopen pic.twitter.com/rNNuRNhwmg
— OptaAce (@OptaAce) August 21, 2025

Unsurprisingly, Djokovic is possibly going to have to overhaul the two biggest names in men’s tennis to lift the crown. Carlos Alcaraz and Jannik Sinner could be the World No. 7’s opponents in the semifinal and final, respectively. While Djokovic leads the head-to-head record against Alcaraz by 5-3, the Sinner challenge seems to be chink in his armor. The Italian top seed is on a five-match winning run vs the 38-year-old elder-statesman, and hasn’t dropped a set against him in their past three encounters.

Novak Djokovic Odds to Win the US Open 2025

Djokovic holds the third position in terms of the pre-tournament favourites to win the 2025 US Open men’s singles title. On the outright winners list, it is Sinner and Alcaraz who have a slight edge over the Serbian legend. However, Djokovic is still an outer favourite to capture the crown.

Novak Djokovic Odds to Win the Title: 9/1

(According to BetMGM: BetMGM offers exclusive promo codes, bonus deals and accurate odds for users upon signing up. Use BetMGM to ace your betting game in all sports!)

(Image Credits: Robert Deutsch, Imagn Images)

ATP

Betting

Carlos Alcaraz

Jannik Sinner

Novak Djokovic

Tennis

US Open

US Open 2025

Sankalp Harikrishnan

A passionate sports fan through and through, I am currently pursuing my MA in Global Sports Journalism. I specialise in tennis and football writing at The Playoffs News, and I have prior experience working at EssentiallySports and Sportskeeda. Born and raised in Bengaluru, India, sport was my safe space right from my childhood. After trying my hand at multiple sports and representing my educational institutions in cricket, badminton and table tennis, I found sports media to be my calling.