Detroit Lions offensive tackle Taylor Decker (68) smiles at warm up before the game between Detroit Lions and Buffalo Bills at Ford Field in Detroit on Sunday, Dec. 15, 2024.

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NFL Week 4 Lions vs Browns Injury Report – Key Updates on Taylor Decker, Al-Quadin Muhammad While Questions Hover Over Browns’ Top Stars in Critical Week 4 Battle

Detroit Lions offensive tackle Taylor Decker (68) smiles at warm up before the game between Detroit Lions and Buffalo Bills at Ford Field in Detroit on Sunday, Dec. 15, 2024.

The Detroit Lions (2-1) will host the Cleveland Browns (1-2) on Sunday, September 28, at Ford Field in downtown Detroit. Detroit enters Week 4 riding a two-game winning streak after an opening-week loss, while Cleveland hopes to avoid falling to 0-3 in 2025. In this matchup Detroit’s high-powered offense meets a Browns defense that has been one of the few bright spots for the team early in the season.

Locked in and ready pic.twitter.com/kBYa1N9GfI
— Detroit Lions (@Lions) September 27, 2025

Detroit has looked like a team on the rise after a shaky start. The Lions racked up 90 points across Weeks 2 and 3, including a 38-30 Monday Night victory over Baltimore. Jared Goff has steered a balanced offense that ranks among the top in EPA/play in recent weeks. With confidence growing in both scoring ability and run defense metrics, Detroit enters Week 4 favored at home, though injuries to key players could test the team’s depth in critical moments.

3️⃣ keys to our matchup against the Lions
— Cleveland Browns (@Browns) September 27, 2025

Cleveland’s season has been turbulent, with a narrow Week 1 loss, a lopsided defeat in Week 2, and a hard-fought Week 3 win over Green Bay, secured by strong defensive play and a walk-off field goal. The Browns’ front seven has stood out, ranking top five against the run, offering hope. Still, the team faces uncertainty with several players managing injuries. As underdogs on the road, Cleveland will lean on its defense to try and contain Detroit for rookie running back Quinshon Judkins to shine in offense.

Detroit Lions Injury Report For Game Against Cleveland Browns

Below is the injury report for the Detroit Lions for Week 4 action against the Cleveland Browns.

Player	Position	Injury	Status
Zach Cunningham	LB	Hamstring	Out
Daniel Thomas	S	Forearm	Out
Sione Vaki	RB	Groin	Out
Taylor Decker	T	Shoulder	Questionable
Al-Quadin Muhammad	EDGE	Knee	Questionable
Derrick Barnes	LB	Knee	(-)

#CLEvsDET injury report presented by Henry Ford Health pic.twitter.com/nfqmaEL1bC
— Detroit Lions (@Lions) September 26, 2025

Detroit enters Week 4 with six players on the injury report, creating questions for the team’s lineup and rotations. Linebacker Zach Cunningham (hamstring), safety Daniel Thomas (forearm), and running back Sione Vaki (groin) are out, leaving holes in both the defensive and offensive schemes.

Tackle Taylor Decker (shoulder) and edge rusher Al-Quadin Muhammad (knee) are questionable, meaning adjustments may be needed in pass protection and pass-rush packages. While linebacker Derrick Barnes (knee) is expected to play, the absences challenge Detroit’s depth.

Cleveland Browns Injury Report For Game Against Detroit Lions

Below is the injury report for the Cleveland Browns for Week 4 action against the Detroit Lions.

Player	Position	Injury	Status
Joel Bitonio	G	Back, Not Injury Related – Rest	(-)
Jack Conklin	OT	Elbow	Questionable
Grant Delpit	S	Back	(-)
Myles Garrett	DE	Not Injury Related – Rest	(-)
Mike Hall Jr.	DT	Knee	(-)
Shelby Harris	DT	Hamstring	(-)
David Njoku	TE	Knee	(-)
Cedric Tillman	WR	Hand, Hip	(-)
Denzel Ward	CB	Shoulder	(-)

Our injury report for Week 4 vs. the Lions
— Cleveland Browns (@Browns) September 26, 2025

Cleveland faces a sizable injury list as it travels to Detroit, with nine players carrying various limitations. Offensive tackle Jack Conklin (elbow) is questionable, while defensive linemen Mike Hall Jr. (knee) and Shelby Harris (hamstring) could impact run-stopping and pass-rush efficiency.

Although key players like Joel Bitonio and Myles Garrett are expected to play, the Browns must navigate these challenges carefully. Tight end David Njoku (knee) and wide receiver Cedric Tillman (hand/hip) remain limited, potentially constraining offensive options, while cornerback Denzel Ward (shoulder) is also nursing an injury.

Mandatory Image Credit: Imagn Images

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Rudra Dubey

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I’m an academic turned sports writer from Raipur, India, specializing in the NFL, MMA, and tennis at The Playoffs. I previously wrote for Sportskeeda and hold a B.A. and M.A. in History. My journey into sports media began far from the field, rooted in the arts and sciences. Funny enough, I didn’t grow up a sports fan; I used to see it all as just noise. But a fateful writing job introduced me to the world of sports, and what began as a gig quickly became a passion. I understood those voices aren’t noise; they’re emotions of true sports fans, and now I am one of them, writing with the same energy I once questioned.