Week 5 of the NFL season comes with a slate of high-stakes battles, as teams look to solidify their early momentum or claw back from shaky starts. With the playoff picture slowly taking shape, every game carries weight where offenses are finding their rhythms, while defenses aim to disrupt. Expect various quarterback duels and teams battling to edge out the other for the top position in their respective divisions.
Injuries and short weeks will add further chaos, which will now test the depth and coaching. From primetime showdowns to afternoon duels, fans can catch every moment of the action, with kickoffs starting Thursday and running through Monday Night.
There are four teams that will not be active this week on the field, including the Chicago Bears, the Green Bay Packers, the Atlanta Falcons, and the Pittsburgh Steelers.
Heading into Week 5 of the NFL, the Detroit Lions are the massive favorites in their matchup against the Cincinnati Bengals at -10.5 Closely followed by them are the Buffalo Bills, who after beating the Saints in Week 4, are now once again huge favorites against the New England Patriots in Week 5 with a spread of -8. The Cardinals are also a huge favorite to beat the Tennessee Titans as the are 7.5-point favorites over the Titans. Along with the Rams, a -8.5 favorite, to beat the 49ers on Thursday.
As for the moneyline, the Lions are a staggering -600 favorites over the Bengals, the Buffalo Bills hold a -475 line, and the Cardinals are at -425. The Rams are also a -450 favorite going against 49ers in Week 5.
Now, let us take a look at the betting odds as per BetMGM for all week 4 matchups, along with the predictions.
The L.A Rams will take on the San Francisco 49ers for Thursday Night Football’s NFC West action in Week 5. The Rams are coming off a win against the Colts, while the 49ers are coming off a loss against the Jacksonville Jaguars in Week 4. The 49ers hold the number one spot at NFC West, compared to the Rams at third. This matchup will decide who’s the top dog in their division.
| Teams | Spread | Total Points | Moneyline |
|---|---|---|---|
| 49ers | +8.5 (105) | 44.5 (-110) | +350 |
| Rams | -8.5 (105) | 44.5 (-110) | -450 |
Prediction: L.A. Rams win
The Browns and the Vikings will face each other for Week 5’s action at London. The Browns are changing their starting QB for Week 5, benching Joe Flacco after a horrible stretch of games. Meanwhile, the Vikings are coming off a close loss against the Pittsburgh Steelers in Week 4, with their QB1 JJ McCarthy in “next phase,” of rehab, with ankle still not fully healed.
| Teams | Spread | Total Points | Moneyline |
|---|---|---|---|
| Vikings | -3.5 (-110) | 36.5 (-102) | -200 |
| Browns | +3.5 (-110) | 36.5 (-118) | +165 |
Prediction: Vikings win the Game
The Colts are taking on the Las Vegas Raiders for Sunday’s NFL games. While the Colts started off their season hot, their biggest test so far, going against the Rams, was not successful. Losing a close contest. The Raiders are 1-3 to start their season, losing a heartbreaking match against the Bears in Week 4. A lot of glaring problems are there with this team, and Geno Smith has not have the best of starts to his season.
Prediction: Colts beat the Raiders
The Saints will host the Giants at their home for their Week 5 action. The Saints have not won a game yet, and have struggled heavily with their QB1 Spencer Rattler. While the Giants are coming off a huge upset over the Chargers after deciding to start Jaxson Dart over Russell Wilson.
Prediction: Giants pull off a win against the Saints
The New York Jets, even after Justin Herbert’s return from concussion still have not won a single game, which has left Aaron Glenn searching for answers. While the Cowboys are coming off drawing against the Green Bay Packers, which was an extremely rare game as it ended in a tie.
| Teams | Spread | Total Points | Moneyline |
|---|---|---|---|
| Cowboys | -2.5 (-115) | 47.5 (-110) | -150 |
| Jets | +2.5 (-105) | 47.5 (-110) | +125 |
Prediction: Cowboys win the contest
The Philadelphia Eagles will host the Denver Broncos for Week 5. The Eagles are arguably the best team in the NFL currently, offensively and defensively. While the Eagles’ receivers still have their own internal problems with the amount of touches they’re receiving, ultimately they are winning and it does not matter. Meanwhile the Broncos are at .500 this season and are coming off a dominant win over the Bengals.
| Teams | Spread | Total Points | Moneyline |
|---|---|---|---|
| Broncos | +3.5 (-110) | 43.5 (-110) | +170 |
| Eagles | -3.5 (-118) | 43.5 (-110) | -210 |
Prediction: Eagles win over the Broncos
The Carolina Panthers will host the Miami Dolphins for Week 5. The Panthers have had a rough start to their season, losing brutally against the Patriots in Week 4, with their only win coming against the Falcons after shutting them down. Meanwhile, the Dolphins managed to win their first game last week, but at what costs? They lost their star WR in Tyreek Hill to a season ending knee injury and we believe their season is or more or less over now despite how they perform.
| Teams | Spread | Total Points | Moneyline |
|---|---|---|---|
| Dolphins | -1.5 (-105) | 44.5 (-110) | -118 |
| Panthers | +1.5 (-115) | 44.5 (-110) | -102 |
Prediction: Panthers win the game
The Baltimore Ravens have surprisingly had a rough start to their season, despite leading the league in points scored per game. Already dealing with injury woes, not even their QB Lamar Jackson is out dealing with a hamstring injury, with no fixed return timeline. While C.J. Stroud and the Texans are coming off a shut down win against the Titans, with the momentum swinging all their way.
Prediction: Texans win the game
The Arizona Cardinals have been a middle of the pack kind of team this season, not showing a lot of improvement. But have not receded either, winning their first two, and now enter week 5 with a losing streak. While the Titans are a different story altogether, and despite their QB showing flashes of potential, the Titans have continued to be one of the worst teams in the league, not winning a single game this season, while getting shut out in Week 4.
| Teams | Spread | Total Points | Moneyline |
|---|---|---|---|
| Titans | +7.5 (-110) | 42 (-110) | +325 |
| Cardinals | -7.5 (-110) | 42 (-110) | -425 |
Prediction: Cardinals win the game
The Seahawks have won three straight games, only losing to the 49ers in Week 1, with their QB Sam Darnold looking more and more comfortable with their offense. While the Tampa Bay Buccaneers had won three straight prior to Week 4, failing to beat the Eagles.
| Teams | Spread | Total Points | Moneyline |
|---|---|---|---|
| Buccaneers | +3.5 (-118) | 44.5 (-110) | +150 |
| Seahawks | -3.5 (-102) | 44.5 (-110) | -185 |
Prediction: Seahawks beat the Buccaneers
Ever since losing Joe Burrow to turf toe injury, the Bengals have fallen off the map, losing brutally against the Broncos and the Vikings, and now they face a Detroit Lions, who have looked unstoppable as of recent. Meanwhile, the Lions have started to find their rhythm and are coming along nicely, despite the loss of their coordinators.
| Teams | Spread | Total Points | Moneyline |
|---|---|---|---|
| Lions | -10.5 (-110) | 49.5 (-110) | -600 |
| Bengals | +10.5 (-110) | 49.5 (-110) | +425 |
Prediction: The Lions win the game
The Chargers have won against a great team in the Kansas City Chiefs, but somehow someway, lost to a Giants team in Week 4 who just changed their QB1 to their rookie Jaxson Dart. Meanwhile, Jayden Daniels is on pace to return of the Commanders’ action for week 5, bringing them back to near full strength, in terms of their injury depleted roster.
| Teams | Spread | Total Points | Moneyline |
|---|---|---|---|
| Commanders | +2.5 (+100) | 48 (-110) | +130 |
| Chargers | -2.5 (-120) | 48 (-110) | -155 |
Prediction: Washington Commanders win the game
The Buffalo Bills have not lost a game yet, thanks to their terrific offense and of course a favorable schedule, with reigning MVP Josh Allen leading the way. Meanwhile, Drake Maye and the Pats are starting find their groove, winning their Week 4 matchup against the Panthers.
Prediction: Buffalo Bills win the Game
The Jaguars have been on a roll this season, previously beating the 49ers in their week 4 matchup, with their QB Trevor Lawrence leading the way. Meanwhile, the Chiefs, after a rough 2-0 start, are starting to come around with back-to-back wins against the Giants and the Ravens, and with Xavier Worthy also back in the lineup.
| Teams | Spread | Total Points | Moneyline |
|---|---|---|---|
| Chiefs | -3.5 (-105) | 46.5 (-110) | -185 |
| Jaguars | +3.5 (-115) | 46.5 (-110) | +150 |
Prediction: Chiefs win the game
(According to BetMGM: BetMGM offers exclusive promo codes, bonus deals and accurate odds for users upon signing up. Use BetMGM to ace your betting game in all sports!)
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