Manchester City return to European action against Bayer Leverkusen on Tuesday looking to steady the ship after another stumble in the Premier League title race. Pep Guardiola’s side slipped to a 2-1 defeat at Newcastle over the weekend, a result that halted their momentum just when they seemed poised to close the gap at the top. However, City remain one of the most consistent forces in the Champions League league phase. They have collected 10 points from their opening four games to sit comfortably inside the top four.
Despite the Newcastle loss, City have been ruthless at home, especially in Europe. Their recent 4-1 dismantling of Borussia Dortmund extended an extraordinary run of 23 Champions League home games without defeat in the league-phase format. The Etihad has seen City score at least twice in each of their last seven home outings, a pattern Guardiola will expect his side to continue on Tuesday night.
| Bets | Moneyline | Moneyline |
| Full Time Result | Manchester City: -450, Bayer Leverkusen: +1100 | Draw: +550 |
| Draw No Bet | Manchester City: -2000 | Bayer Leverkusen: +800 |
| Total Goals | Over 3.5: -110 | Under 3.5: -125 |
| Manchester City to Win and Both Teams to Score | Yes: +140 | No: +115 |
| Bayer Leverkusen to Win and Both Teams to Score | Yes: +1450 | No: +1800 |
(Odds via BetMGM)
On the other hand, Bayer Leverkusen arrive in Manchester in some of their best form of the season. Since Kasper Hjulmand replaced Erik ten Hag, the Bundesliga side have undergone a noticeable resurgence. They claimed their first Champions League win of the campaign with a disciplined 1-0 victory at Benfica. That result has been supported by a flurry of success in Bundesliga, including a 6-0 demolition of Heidenheim and a 3-1 win at Wolfsburg.
Those back-to-back Bundesliga wins have lifted Leverkusen to third in the table and restored belief after a shaky start to the season. Seven of their last nine matches across competitions have ended in victory, and they travel to Manchester with confidence and momentum. Notably, Tuesday’s clash will mark the first-ever competitive meeting between Manchester City and Bayer Leverkusen.
Even so, City’s dominant European home form and their habit of responding emphatically after setbacks set the stage for another strong Etihad performance. With Guardiola’s side eager to erase the sting of their league defeat and secure early passage into the knockout stage, this matchup promises intensity, quality, and potentially plenty of goals.
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Over 3.5 Goals looks entirely justified given how both teams are playing. Manchester City have cleared this line in three of their last five matches, including 4-1 and 3-1 wins over Dortmund and Swansea, Meanwhile, Leverkusen arrive with an equally explosive attack, scoring 9 goals in their last two outings. With both sides consistently producing high-scoring games and entering this clash in strong offensive form, this match is likely to cross the 3.5-goal mark.
Given Erling Haaland’s price is extremely short, Foden offers far better value. He’s been one of City’s more reliable Champions League contributors this season with two goals in three UCL games. His creative influence often puts him in advanced shooting positions. With Foden consistently involved in City’s best attacking sequences, backing him at +195 presents a value play.
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| Picks | Moneyline |
| Erling Haaland to score anytime | -285 |
| Erling Haaland to score first | +175 |
| Jeremy Doku to assist | +180 |
| Jeremy Doku to score anytime | +250 |
| Phil Foden to score anytime | +195 |
Final Prediction: Manchester City 3-1 Bayer Leverkusen
While City are overwhelming favourites at home, Leverkusen’s recent attacking fluency and renewed discipline under Hjulmand suggest they are capable of making this a competitive contest. Nevertheless, City will be pumped up to get back to winning ways after the defeat against Newcastle United in Premier League.
The Manchester City vs Bayer Leverkusen clash is on November 25, 2025, at Ethiad stadium.
Manchester City are favorites to win with a moneyline at -450, to draw at +550 and for Bayer Leverkusen to win at +1100.
Erling Haaland to score anytime: -285
Phil Foden to score anytime: +195
Bettors can explore a variety of betting options on BetMGM, including full-time results, over/under goals, and player props for this clash.