Mandatory Credit: Geoff Burke-Imagn Images

Lorenzo Musetti vs. James Duckworth Head-to-Head, Prediction, and Betting Odds for ATP National Bank Open 2025 Second Round

Top-seeded Musetti opens against Duckworth as he looks to continue his breakthrough 2025 season.

Mandatory Credit: Geoff Burke-Imagn Images

Third seed Lorenzo Musetti begins his Toronto campaign against Australian qualifier James Duckworth in the second round of the 2025 National Bank Open. The Italian received a first-round bye, while Duckworth cruised past Juncheng Shang in straight sets to earn his spot.

Musetti is enjoying the best season of his career, climbing to a career-high world No. 6 last month. After a solid start with quarterfinals in Hong Kong and Argentina, he hit a brief slump but rebounded impressively with a finals run in Monte Carlo, losing to Carlos Alcaraz in three sets, followed by semifinal finishes in Madrid, Rome, and Roland Garros. He did, however, withdraw from Rio and Barcelona due to calf and thigh injuries. So far, the Italian has fired 120 aces, winning 69% of first-serve points and 33% of first-serve return points, and converting 39% of 320 break points.

It’s time for lethal Lorenzo 🇮🇹

Come Tuesday, July 29th during our day session to see Lorenzo Musetti charge into the first round at the National Bank Open ☀️

TICKETS 🎟️👉 https://t.co/yuLp5wyVir pic.twitter.com/WRM7kTl3zP
— National Bank Open (@NBOtoronto) July 28, 2025

Duckworth, meanwhile, has had a patchy year, though his highlights include a title in Challenger San Luis Potosi, a runner-up finish in Morelia, a round of 16 appearance at Eastbourne, and a quarterfinal run in Mifel. He’s hit 96 aces, won 69% of first-serve points, and converted 32% of 73 break points.

Lorenzo Musetti vs. James Duckworth Head-to-Head Record

James Duckworth leads the head-to-head against Lorenzo Musetti 1-0, with their only meeting coming in Paris back in 2021. The Aussie came through in three sets on that occasion.

Year	Event	Round	Winner	Score
2021	Paris	Round of 32	James Duckworth	6-3, 3-6, 6-3

James Duckworth takes the last match of Day 2️⃣ ‼️

He takes down Juncheng Shang in straight sets to punch his ticket to the next round 👊

@nationalbankofcanada pic.twitter.com/jcFOj8FtyS
— National Bank Open (@NBOtoronto) July 28, 2025

Lorenzo Musetti vs. James Duckworth Comparison

Lorenzo Musetti	Category	James Duckworth
10	Current Ranking	106
157-121	Career W-L	69-117
25-10	YTD W-L	4-9
2	Career Titles	0
0	Grand Slams	0
0	YTD Titles	0

Lorenzo Musetti vs. James Duckworth Prediction

Musetti comes in with top-10 momentum and a string of deep clay runs under his belt. While Duckworth has the tools to test him, the Italian’s shot variety and recent form make him the clear favorite to advance.

Players able to collect 5+ ATP Top 10 wins in 2025

· 🇪🇸 Carlos Alcaraz (8)
· 🇮🇹 Jannik Sinner (7)
· 🇮🇹 Lorenzo Musetti (5)
· 🇪🇸 Alejandro Davidovich (5) pic.twitter.com/V4hkavr0ye
— Mario Boccardi (@boccardi_marioo) July 27, 2025

Prediction: Lorenzo Musetti in straight sets

Lorenzo Musetti vs. James Duckworth ATP National Bank Open 2025 Betting Odds

Bookmakers heavily back Musetti at 1/7 to move through, reflecting his breakout year. Duckworth, priced at 23/5, will need a near-perfect performance to pull off the upset.

Here are the betting odds according to BetMGM:

Lorenzo Musetti: 1/7

James Duckworth: 23/5

Here are the odds for total games as well as total sets for both players (sourced via BetMGM):

Total Games Over 18.5: 2/5

Total Games Under 21.5: 8/11

Musetti to win: Set 1 – 7/25

Duckworth to win: Set 1 – 7/2

Total Sets Over 2.5: 41/20

Total Sets Under 2.5: 7/20

(According to BetMGM: BetMGM offers exclusive promo codes, bonus deals and accurate odds for users upon signing up. Use BetMGM to ace your betting game in all sports!)

Mandatory Image Credit: Geoff Burke-Imagn Images

James Duckworth

Lorenzo Musetti

National Bank Open 2025

Rudra Dubey

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I’m an academic turned sports writer from Raipur, India, specializing in the NFL, MMA, and tennis at The Playoffs. I previously wrote for Sportskeeda and hold a B.A. and M.A. in History. My journey into sports media began far from the field, rooted in the arts and sciences. Funny enough, I didn’t grow up a sports fan; I used to see it all as just noise. But a fateful writing job introduced me to the world of sports, and what began as a gig quickly became a passion. I understood those voices aren’t noise; they’re emotions of true sports fans, and now I am one of them, writing with the same energy I once questioned.