Mandatory Credit: Steven Bisig-Imagn Images

Kansas City Chiefs vs. Seattle Seahawks Preview, Prediction, and Betting Odds for NFL Preseason Week 2

NFL Preseason Week 2 pits the Seattle Seahawks against the Kansas City Chiefs.

Mandatory Credit: Steven Bisig-Imagn Images

As the 2025 NFL preseason moves into Week 2, the Kansas City Chiefs visit Lumen Field to face the Seattle Seahawks on Friday night. Last week, the Chiefs fell 20-17 to the Arizona Cardinals. For week 2, Patrick Mahomes and Travis Kelce are unlikely to see the field, but the Chiefs will still rotate several starters to test depth against a Seahawks squad eager to build momentum. Fans can expect a competitive, fast-paced matchup.

Patrick Mahomes dishes it to Jason Brownlee for the Chiefs' first preseason TD 😤pic.twitter.com/WIup8JHAWL
— ClutchPoints (@ClutchPoints) August 10, 2025

Last week, Chiefs quarterback Bailey Zappe threw for 70 yards and two interceptions, while Gardner Minshew and Chris Oladokun combined for 93 passing yards. Oladokun also paced the ground game with 26 rushing yards. On defense, Jeffrey Bassa led Kansas City with six tackles, while Janarius Robinson and Jaden Hicks each made key plays with a sack and interception, respectively.

Preseason Week 2.

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Presented by Muckleshoot Indian Tribe pic.twitter.com/DYQSyVpok9
— Seattle Seahawks (@Seahawks) August 13, 2025

Seattle opened the preseason with a 23-23 tie against the Las Vegas Raiders, leaning heavily on their backups. Drew Lock threw for 147 yards with one touchdown and one interception, while Jalen Milroe added 61 passing yards. The Seahawks’ ground game gained 170 yards, led by George Holani’s 61-yard effort. On the defensive side, D’Eryk Jackson led the team with six tackles, while Connor O’Toole and Josh Jobe added a sack and interception.

Kansas City Chiefs vs Seattle Seahawks NFL Preseason Week 2 Prediction

The Seahawks are more likely to win, but the Chiefs’ young talent could make this preseason clash intriguing. Even without Patrick Mahomes and Travis Kelce seeing significant action, Kansas City’s up-and-comers showed promise in Week 1, particularly in the backfield and receiving corps. While Seattle’s starters are expected to play more extended snaps, giving fans a glimpse of the team’s depth and chemistry.

The Las Vegas Raiders and the Seattle Seahawks tie 23-23 during an NFL Preseason 2025 game at Lumen Field on August 07, 2025 in Seattle, Washington. (Steph Chambers/Getty Images) pic.twitter.com/nxjU0EdCrs
— Steph Chambers (@StephChambers76) August 8, 2025

Match Prediction: Seahawks win 23-21

Kansas City Chiefs vs Seattle Seahawks NFL Preseason Week 2 Betting Odds

The Seahawks are favorites at 16/25, reflecting their stronger depth and preseason form. The Chiefs, at 13/10, offer value for those backing an upset from the Chiefs, given new talents.

Here are the betting odds according to BetMGM:

Kansas City Chiefs: 16/25

Seattle Seahawks: 13/10

The over-under for total points as per BetMGM is as follows:

Total Points Over 39: 10/11

Total Points Under 39: 10/11

Point Spread Chiefs +3: 10/11

Point Spread Seahawks -3: 10/11

(According to BetMGM: BetMGM offers exclusive promo codes, bonus deals and accurate odds for users upon signing up. Use BetMGM to ace your betting game in all sports!)

Mandatory Image Credit: Steven Bisig-Imagn Images

Kansas City Chiefs

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Week 2

Rudra Dubey

nfl

mma

I’m an academic turned sports writer from Raipur, India, specializing in the NFL, MMA, and tennis at The Playoffs. I previously wrote for Sportskeeda and hold a B.A. and M.A. in History. My journey into sports media began far from the field, rooted in the arts and sciences. Funny enough, I didn’t grow up a sports fan; I used to see it all as just noise. But a fateful writing job introduced me to the world of sports, and what began as a gig quickly became a passion. I understood those voices aren’t noise; they’re emotions of true sports fans, and now I am one of them, writing with the same energy I once questioned.