Jaguars vs Seahawks Predictions, Odds and Best Bets For Week 6 of the 2025-26 NFL Season

Seattle Seahawks make the long journey down south to take on the Jacksonville Jaguars in week 6!

Jaguars vs Seahawks Predictions, Odds and Best Bets For Week 6 of the 2025-26 NFL Season

This week 6 game features the 4-1 Jacksonville Jaguars taking on the 3-2 Seattle Seahawks. This game promises to be an electric one, given that both teams are playing well to start the season.

Game Details:

Time: 1:00 p.m. ET
Date: Sunday, October 12, 2025
Venue: EverBank Stadium, Jacksonville, Florida
TV Channel: FOX
Streaming: NFL+

Recommended bets and updated odds

Recommended Bets	FanDuel	BetMGM
Sam Darnold 225+ Passing Yards	-162	-175
Jaxon Smith-Njigba 90+ Receiving Yards	+134	+120
Trevor Lawrence 200+ Passing Yards	-235	-278

Analysis and Rationale

Sam Darnold is coming off a huge performance in week 5 with 341 passing yards. But, while that was a one-off, he has been consistently passing for over 200 yards with three games over 225. Additionally, the Jaguars’ strong run defense could mean that Seattle ends up throwing the ball more.

Jaxon Smith-Njigba has embraced the role of WR1 head-on and is the go-to guy for Sam Darnold on the Seahawks offense. Smith-Njigba has over 100 receiving yards in 3 of his 5 games thus far, and another game over 90+. Moreover, the Jaguars’ pass defense is one of their weaknesses.

Trevor Lawrence probably played one of his best games last week against the Chiefs. Overall, he has three games passing over 200 yards, but the Seahawks are equally strong against the run. Look for Lawrence to air it out more, especially after Brian Thomas Jr. and Travis Hunter’s performances in week 5.

Another one at The 'Bank..@FLBlue | #SEAvsJAX pic.twitter.com/POg46bE0Ws
— Jacksonville Jaguars (@Jaguars) October 9, 2025

Jaguars vs Seahawks Prediction

Sunday’s game between the Jaguars and the Seahawks doesn’t feature any real standout team. Both teams have been playing high-quality football. Both teams are close when it comes to scoring points, though the Seahawks hold the edge with around 29 points per game as opposed to the Jaguars’ 25.

Defensively, both teams are more or less evenly matched in terms of points allowed. The one aspect where Jacksonville holds the edge is the turnover battle, where they lead the league with a +8 differential, while the Seahawks are at -1.

That being said, Sam Darnold and the Seahawks’ offense have been the better side. If the game comes down to a quarterback duel, Darnold seems to have the better chance.

Prediction: Seattle Seahawks to win.

Week 6 Jaguars vs Seahawks Betting Odds and Spread

The moneyline and spread show that the Jacksonville Jaguars are slight favorites in this matchup against the Seattle Seahawks. (Sourced from FanDuel).

	Moneyline	Spread	Total Points
Jacksonville Jaguars	-112	-1.5 (-102)	O 47.5 (-105)
Seattle Seahawks	-104	+1.5 (-120)	U 47.5 (-115)

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Jaguars vs Seahawks Best Bets

Here are the over/under and best player bets for the Jacksonville Jaguars and the Seattle Seahawks, as per FanDuel.

Jacksonville Jaguars Over/Under Odds

Below are some of the best over/under bets for the Jacksonville Jaguars.

Over/ Under Bets	Over	Under
Trevor Lawrence Pass Completions	22.5 (-102)	22.5 (-130)
Brian Thomas Jr. Total Receptions	4.5 (-200)	4.5 (+148)
Travis Etienne Rushing Yards	64.5 (-114)	64.5 (-114)

Jacksonville Jaguars Best Player Bets

Below are some of the best player bets for the Jacksonville Jaguars.

Trevor Lawrence interception: -168
Brian Thomas Jr. 60+ Receiving Yards: -120
Travis Etienne 50+ Rushing Yards: -260

If you’re looking for a complete guide to the best NFL betting sites, we’ve got you covered

Prepping for Jacksonville.

Presented by @Gatorade pic.twitter.com/97OtF7wjfi
— Seattle Seahawks (@Seahawks) October 9, 2025

Seattle Seahawks Over/Under Odds

Below are some of the best over/under bets for the Seattle Seahawks.

Over/ Under Bets	Over	Under
Sam Darnold Pass Completions	21.5 (-114)	21.5 (-114)
Jaxon Smith-Njigba Total Receptions	5.5 (-162)	5.5 (+122)
Kenneth Walker III Rushing Yards	52.5 (-114)	52.5 (-114)

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Seattle Seahawks Best Player Bets

Below are some of the best player bets for the Seattle Seahawks.

Sam Darnold Most Passing Yards: -142
Cooper Kupp 30+ Receiving Yards: -270
Kenneth Walker III 50+ Rushing Yards: -138

The above odds are sourced from FanDuel. Use FanDuel to ace your betting game in all sports!

FAQs

What is the over/under for total points for the Jaguars vs Seahawks game?

The over/under for total points in the Jaguars vs Seahawks game is set at 47.5.

What is the point spread for the Jaguars vs Seahawks game on Sunday?

The Jaguars come into the game as slight 1.5-point favorites over the Seahawks.

What is the moneyline for the Jaguars vs Seahawks game in week 2?

The Jaguars are the favorites with a moneyline of -112, while the Seahawks are the underdogs at -104.

Mandatory Credit: Steven Bisig-Imagn Images

Devavrat Kulkarni

nfl

I am a content writer for the NFL team, and joined The Playoffs after working with Sportskeeda and NFL Analysis as an NFL writer. After starting my professional career as a French-to-English translator, working as a content writer is a new adventure for me. I started out in the sports media field for two main reasons: my love for sports in general, especially the NFL, NBA, and Tennis, as well as my passion for writing. The best part of this job is that I get to write a variety of pieces with the freedom to explore content from various angles. It also enables me to stay up to date with the sporting world, which otherwise can be difficult to do in the day-to-day grind. In a world full of chaos, sports unite and entertain like nothing else!