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Giants vs Eagles Predictions, Odds and Best Bets For Week 6 Thursday Night Football

Eric Divakaran
American Football / NFL
10/10/2025 – 01:15
New York Giants
VS
01:15
10/10/2025
Philadelphia Eagles
Odds updated on October 9, 2025 at 12:40 am

Giants vs Eagles Predictions, Odds and Best Bets For Week 6 Thursday Night Football

The New York Giants will take on the Philadelphia Eagles for Thurday Night’s Football action on Week 6. The Giants have had a rough start to their season, losing to the New Orleans Saints and Spencer Rattler in Week 5 and only winning a single game so far against the Los Angeles Chargers. The Giants decided to bench Russell Wilson and start their rookie QB Jaxson Dart, and while he won New York their first game of the season, he second start was less than ideal. Dart threw two interceptions against the Saints, proving that he has a long way to go before becoming a household name in the NFL.

Meanwhile, the Philadelphia Eagles are coming off a loss against the Denver Broncos in Week 5, after going undefeated for four-straight weeks to start the season. The Eagles have had their own share of problems this season, even though they are 4-1 for the season. Some of their glaring problems include their defense, which has not been as good as it was last season, and their offensive lapses with Saquon Barkley having a very slow start to his season, and A.J. Brown complaining about lack of touches. The champs scored just 17 point against the Broncos’ stout defense and even tho Jalen Hurts has been excellent this season, the rest of the team needs to pick up the pace in order for them to contend for the title yet again.

Game Details

  • Time: 8:15 p.m. ET
  • Date: October 9, 2025
  • Location: MetLife Stadium
  • TV: Amazon Prime Video
  • Streaming: Fubo

Recommended bets and updated odds

Recommended BetsFanDuelBetMGM
Jalen Hurts 2+ TD passes+152+160
Cam Skattebo Anytime TD+155+145
Eagles moneyline-104-104

Analysis and Rationale

Jalen Hurts has thrown 7 touchdows in his 5 games so far. However, all seven of his passing touchdowns have come in the last three games. He has thrown at least 2 touchdowns in all three games since week3. 

The Giants may need to rely heavily on Cam Skattebo and the run game in this matchup because they are down two key wide receivers. Malik Nabers is out for the season and Darius Slayton is dealing with an injury. 

The Eagles to win this game is one of the better bets. There is a huge gap in both teams in terms of the talent available on the roster. Moreover, this is a battle between one of the top teams in the league against one of the bottom teams.

Giants vs Eagles Predictions

We expect the Philadelphia Eagles to take down the New York Giants. Despite Philly’s shaky pass and rushing offense and a recent fourth-quarter collapse against Denver, they are still way too talented for the Giants to overcome. Jalen Hurts may look for his receivers in this game, given the Giants’ shaky pass defense. And even if the Giants find a way to stop the passing game, stopping Saquon Barkley and his rushing attempts is a very tall task as they rank 26th in run defense.

Rookie QB Jaxson Dart’s turnovers in their last game against the Saints doomed the Giants, and you could expect the same in this game, given the Eagles’ dominant defensive unit, which can at times shut everything down. Expect a 24-17 victory for the Eagles.

Prediction: Eagles win the game 24-17

Week 6 TNF Giants vs Eagles Betting Odds and Spread

Looking at the Spread and the moneyline, the Eagles are the favorites to win the contest on the road, against the New York Giants, according to BetMGM

TeamsSpreadTotal PointsMoneyline
Eagles-7.5 (-105)40.5 (-110)-400
Giants+7.5 (-115)40.5 (-110)+310
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Giants vs Eagles Best Bets

Here are over/under and best player bets for the New York Giants and the Philadelphia Eagles, according to BetMGM

New York Giants Over/Under Odds

Listed below are over/under odds for the New York Giants, as per BetMGM

Over/Under BetsOverUnder
Jaxson Dart Passing Yards178.5 (-115)178.5 (-115)
Wan’Dale Robinson Receiving Yards 43.5 (-115)43.5 (-115)
Cam Skattebo Rushing Yards45.5 (-115)45.5 (-115)

New York Giants Best Player Bets

Here are some of the best player bets for the New York Giants, as per BetMGM

  • Jaxon Dart to throw over 0.5 INTs: -140
  • Cam Skattebo Anytime TD scorer: +145
  • Wan’Dale Robinson under 5.5 receptions made: -150
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Philadelphia Eagles Over/Under Odds

Listed below are over/under for the Philadelphia Eagles, as per BetMGM

Over/Under BetsOverUnder
Jalen Hurts Passing yards 198.5 (-115)198.5 (-115)
A.J. Brown Receiving yards63.5 (-115)63.5 (-115)
Saquon Barkley Rushing yards84.5 (-115)84.5 (-115)

Philadelphia Eagles Best Player Bets

Here are some of the best player bets for the Philadelphia Eagles, as per BetMGM

  • Saquon Barkley anytime touchdown scorer: -160
  • Jalen Hurts anytime touchdown scorer: -135
  • Jalen Hurts under 1.5 passing touchdowns: -200
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FAQs

Who is favored to win between the Giants and the Eagles?
The Philadelphia Eagles are 7.5-point favorites to win the matchup against the New York Giants.

What is the over/under total for the game?
The over/under for total points is set at 40.5.

What is the predicted score for the Giants vs Eagles game?
We expect the Eagles to take down the Giants in Week 6’s Thursday Night Football, and the final score to be 24-17.


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I cover the National Football League and things cannot get better than that. I always dreamed to play football or basketball professionally since I’m built like a Running Back. But now that I can’t, since I’m technically in the “Unc” age, I thought why not pick a career in sports industry? So here I am, doing what I love, and hoping that the Commanders win the Super Bowl. I give love to players when it’s due, but can be critical about their performances at the same time. Enough about me, now let my articles do all the talking. 

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