Sports
Picks & Odds
Betting Guide
Casinos
Missouri
NFL NFL
Sports Picks & Odds Betting Guide Casinos Missouri
Gambling is prohibited for underage individuals | Commercial content | Regional restrictions may apply | T&Cs apply | Play responsibly

Tampa Bay Buccaneers vs New England Patriots Predictions, Odds, and Best Bets for Week 10 NFL 2025-26 Season

Eric Divakaran
American Football / NFL
09/11/2025 – 19:00
Tampa Bay Buccaneers
VS
19:00
09/11/2025
New England Patriots
Odds updated on November 6, 2025 at 7:19 pm

The Tampa Bay Buccaneers will host the New England Patriots for Week 10’s exciting NFC vs AFC Matchup, live from Raymond James Stadium. The Buccaneers are 6-2 for the season and are slowly starting to become the clear favorites to once again, win the NFC South division. They are coming off a dominant win against the New Orleans Saints, holding them to just three points while scoring 23 points. Baker Mayfield has been amazing this season, and despite all the injuries with players in and out of the lineup, the Bucs have found ways to continue winning.

View this post on Instagram

A post shared by Tampa Bay Buccaneers (@buccaneers)

Meanwhile, the New England Patriots have been equally dominant this season, with their second year QB Drake Maye leading the way. The Patriots have looked like a Super Bowl contending team so far and are 7-2 this season, leading the AFC East ahead of the Buffalo Bills. They are currently on a roll, winning 6-straight games and are hoping to extend the streak to 7, by beating a formidable team.

Recommended Bets and Updated Odds

Recommended BetsFanduelBetMGM
Stefon Diggs longest reception over 22.5-110-105
Drake Maye over 1.5 passing TDs-152-140
Baker Mayfield over 1.5 passing TDs -168-140
Bet $5 Win $250 in Bonus Bets
Click to reveal code
COPIED
F A N D U V I P
Claim $250
21+ and present in AZ/CO/CT/IA/IL/IN/KS/LA (permitted parishes only) /MA/MD/MI/NJ/NY/OH/PA/TN/VA/WV/WY. Minimum $10 first deposit required. Promotion Bonus will be credited to your account within 72 hours settlement of Qualifying Wager. First online real money wager only (minimum $5). Bonus issued as non-withdrawable bonus bets that expires in 14 days. Bonus bets and NFL Sunday Ticket code will be issued within 72 hours of bet placement. See full terms at sportsbook.fanduel.com.

Rationale and Analysis

Stefon Diggs could catch a reception longer than 22.5 because in the Patriot’s system around Drake Maye, Diggs has been used as a deep threat target and in 4 out of 9 games so far, Diggs has crossed the 22.5 mark threshold. The Buccaneers have a weak pass defense which ranks 22nd in the league, allowing 228.8 yards on average, which makes us believe that this is a safe bet.

Drake Maye has been on a tear this season and has thrived in the last four games, scoring at least 2 TDs each. Looking at the Bucs weak pass defense, and 13th ranked scoring defense, we believe that Maye will have 2 or more TDs in this game. The Patriots’ system revolving around Maye’s arm and their pass heavy offense, should allow Maye to score effortlessly.

Baker Mayfield should be able to throw for over 1.5 passing TDs as he’s scored at least 1 TD in every single game, expect against the Raiders last week, and the Buccaneers’ heavy reliance in his arm. The Patriots are vulnerable against the pass, ranking 19th, and look for Mayfield to exploit that weakness using his arm.

Buccaneers vs Patriots Prediction

We expect the New England Patriots to pull off an upset against the Tampa Bay Buccaneers, as they are on a six-game winning streak with all the momentum in their favor. While we expect the Buccaneers to give them a tough fight, the Patriots No.1 ranked rush defense, and their 5th ranked scoring defense, should prove to be enough to stop Tampa.

Prediction: Patriots win the game 28-21

View this post on Instagram

A post shared by New England Patriots (@patriots)

Week 10 Buccaneers vs Patriots Spread and Betting Odds

Looking at the spread and the moneyline, the Tampa Bay Buccaneers are the slight favorites to walk away with a victory against the New England Patriots, as per BetMGM

TeamsSpreadTotal PointsMoneyline
Patriots +2.5 (-110)48 (-110)+120
Buccaneers -2.5 (-110)48 (-110)-145
Get up to $1,500 Back in Bonus Bets
Click to copy code
COPIED
TPOPICKS
CLAIM $1500
21+. AZ/CO/IL/IN/IA/KS/LA/MD/MA/MI/NJ/OH/PA/TN/ VA/WV/WY only. Offer not available in DC/MS/NV/NY/PR. New customers only. Qualifying deposit (min $10) and first real money wager required. If qualifying bet settles as a loss, user is refunded 100% in non-withdrawable bonus bets up to $1,500. Full T&Cs can be found on betmgm.com.

If you’re looking for a complete guide to the best NFL betting sites, we’ve got you covered.

Buccaneers vs Patriots Best Bets

Here are some of the best player bets and the over/under odds for the Tampa Bay Buccaneers and the New England Patriots, as per BetMGM

Tampa Bay Buccaneers Over/Under Odds

Listed below are over/under odds for the Tampa Bay Buccaneers, as per BetMGM.

Over/Under BetsOverUnder
Baker Mayfield passing TDs 1.5 (-140)1.5 (+105)
Rachaad White rushing yards 47.5 (-115)47.5 (-118)
Emeka Egbuka receiving yards 71.5 (-115)71.5 (-115)

Tampa Bay Buccaneers Best Player Bets

Here are some of the best player bets for the Tampa Bay Buccaneers, as per BetMGM.

  • Baker Mayfield over 1.5 passing TDs: -140
  • Baker Mayfield over 300+ passing yards: +280
  • Emeka Egbuka over 24.5 longest reception: -120

New England Patriots Over/Under Odds

Listed below are over/under odds for the New England Patriots, as per BetMGM.

Over/Under OddsOverUnder
Drake Maye passing yards 246.5 (-115)246.5 (-115)
Drake Maye rushing yards 30.5 (-110)30.5 (-118)
Stefon Diggs Receiving Yards 57.5 (-115)57.5 (-115)

New England Patriots Best Player Bets

Here are some of the best player bets for the New England Patriots, as per BetMGM.

  • Drake Maye over 1.5 passing TDs: -135
  • Drake Maye 50+ rushing yards: +290
  • Stefon Diggs over 22.5 longest reception: -105
Get up to $1,500 Back in Bonus Bets
Click to copy code
COPIED
TPOPICKS
CLAIM $1500
21+. AZ/CO/IL/IN/IA/KS/LA/MD/MA/MI/NJ/OH/PA/TN/ VA/WV/WY only. Offer not available in DC/MS/NV/NY/PR. New customers only. Qualifying deposit (min $10) and first real money wager required. If qualifying bet settles as a loss, user is refunded 100% in non-withdrawable bonus bets up to $1,500. Full T&Cs can be found on betmgm.com.

(According to BetMGM: BetMGM offers exclusive promo codes, bonus deals and accurate odds for users upon signing up. Use BetMGM to ace your betting game in all sports!)

FAQs

Who is favored to win between the Buccaneers vs Patriots?
The Buccaneers are 2.5-point favorites to win the matchup against Patriots.

What is the over/under total for the game?
The over/under for total points is set at 48.

What is the predicted score for the Buccaneers vs Patriots game?
We expect the Patriots to take down the Buccaneers in a close battle, and the Final score to be 28-21.

nba nba
nfl nfl
mma mma

I cover the National Football League and things cannot get better than that. I always dreamed to play football or basketball professionally since I’m built like a Running Back. But now that I can’t, since I’m technically in the “Unc” age, I thought why not pick a career in sports industry? So here I am, doing what I love, and hoping that the Commanders win the Super Bowl. I give love to players when it’s due, but can be critical about their performances at the same time. Enough about me, now let my articles do all the talking. 

Read more