Mandatory Credit: Aaron Doster-Imagn Images

Andrey Rublev vs. Alexei Popyrin Head to Head, Prediction and Betting Odds for ATP Cincinnati Open 2025 Round of 32

Mandatory Credit: Aaron Doster-Imagn Images

No. 9 seed, Andrey Rublev and Alexei Popyrin will meet for the first time since 2024 Canadian Open final. The duo will lock horns in the round of 32 fixture at the Cincinnati Masters. Rublev dispatched Learner Tien in straight sets, while Popyrin overcame Martin Landaluce to reach the third round.

Also Read: Benjamin Bonzi Knocks Out Stefanos Tsitsipas from Cincinnati Open to Reach Maiden 4th Round at Masters 1000 Event

Andrey Rublev had a roller-coaster ride this season with a 27-18 record. The 27-year-old reached the quarterfinal in his most recent event at Toronto. The four-time US Open quarterfinalist has only one singles title which came in Qatar after losing in the opening round of the Australian Open. In previous Masters event in Canada, Rublev overcame players Fokina and Sonego. In previous game at Cincinnati, he showed dominant display against Tien, who beat him in Citi DC Open last month. He had a great history at Cincinnati, finishing as runner-up in 2021, quarterfinallist in 2019 and 2024.

Andrey's revenge 😜

2021 finalist @AndreyRublev97 flips the script on Learner Tien, 7-6 6-3. #CincyTennis pic.twitter.com/IGMyluWUS3
— Tennis TV (@TennisTV) August 10, 2025

Alexei Popyrin is a giant-killer in big events and he showed it when he outclassed Rubelv to win the National Bank Open last year. The Australian ace is taking charge of his country after the elimination of Alex de Minaur. Popyrin dropped a 12-4 record against top-20 players at Masters events, including two wins against Rublev. The Aussie reached the quarterfinals in Toronto where he surprised Rune and Medvedev before losing to Zverev in three sets. This year, he had a quarterfinal run in Monte Carlo as well and secured fourth-round finish in Roland Garros.

🇦🇺 Alexei Popyrin (21) navigates his way into Round 3 of the ATP 1000 Cincinnati Open 🇺🇸 with a 7-6(3), 6-3 win over 🇪🇸 Martin Landaluce (Q) – R64.

Next: Andrey Rublev

Popyrin leads the H2H 2-1. pic.twitter.com/jwqwAkUhky
— The First Serve (@TheFirstServeAU) August 10, 2025

Andrey Rublev vs. Alexei Popyrin Head to Head Record

Alexei Popyrin holds the 2-1 lead over Andrey Rublev in the ATP H2H meetings. The Australia ace won their two matches last year in 1000 Masters event. His most famous victory came in the final of last year’s ATP Masters 1000 Canada.

Year	Event	Round	Winner	Score
2024	ATP Masters 1000 Canada	Final	Alexei Popyrin	6-2 6-4
2024	ATP Masters 1000 Monte-Carlo	Round of 32	Alexei Popyrin	6-4, 6-4
2023	Vienna	Round of 32	Andrey Rublev	7-6(5), 6-4

Andrey Rublev vs. Alexei Popyrin Career Comparison

Andrey Rublev	Category	Alexei Popyrin
11	Current Ranking	19
358–201	Career W-L	108–129
27-18	YTD W-L	16-18
17	Career Titles	3
0	Grand Slams	0
1	YTD Titles	0

Andrey Rublev vs. Alexei Popyrin 2025 Cincinnati Open Prediction

Alexei Popyrin’s solid record against top-20 players in the Masters event make him a giant-killer. The Australian ace defeated Rublev twice in 1000 Masters. He thrives when serve and forehand click. Rubelv can counter him through long rallies and first serve where Popyrin made struggles.

Prediction: Andrey Rublev to win in three sets.

Andrey Rublev vs. Alexei Popyrin 2025 Cincinnati Open Betting Odds

With odds slightly favoring Rublev at 8/15 over Popyrin at 13/8, the bookmakers see momentum on the Russian’s side.

Here are the betting odds according to BetMGM:

Andrey Rublev: 8/15
Alexei Popyrin: 13/8

Here are the odds for total games as well as total sets for both players (sourced via BetMGM):

Total Sets Under 2.5: 13/20
Total Sets Over 2.5: 129/100
Total Games Under 21.5: 8/15
Total Games Over 21.5: 6/4
Rublev to win: Set 1 – 8/13
Fokina to win: Set 1 – 11/8

(According to BetMGM: BetMGM offers exclusive promo codes, bonus deals and accurate odds for users upon signing up. Use BetMGM to ace your betting game in all sports!)

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Mandatory Credit: Aaron Doster-Imagn Images

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