NFC West teams, the Rams and the Seahawks are massive favorites in their respective Week 13 matchups!
It is officially Thanksgiving week in the NFL, and once again this season, the league will have a triple-header on ‘Thanksgiving Day’ to kick start Week 13 of the 2025-26 NFL regular season.
The extensive action begins with the Green Bay Packers taking on the Detroit Lions in the early afternoon game, followed by the Kansas City Chiefs against the Dallas Cowboys in the late afternoon window. The Cincinnati Bengals and the Baltimore Ravens will close out the Thursday games with Thursday Night Football (TNF).
NFL Week 13 Team Picks
Here are some of the best picks ahead of the full slate of Week 13 games as per the odds on FanDuel.
Seattle Seahawks win and cover the spread (-10.5) against the Minnesota Vikings: -110
New England Patriots win and cover the spread (-7.5) against the New York Giants: -105
Denver Broncos win and cover the spread (-6.5) against the Washington Commanders: -110
Chicago Bears to win over the Philadelphia Eagles: +265
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NFL Week 13 Spreads
The spreads for this week have the Los Angeles Rams as massive favorites at -10.5 points over the Carolina Panthers. Similarly, the Seattle Seahawks are also huge 10.5-point favorites over the Minnesota Vikings. The Los Angeles Chargers come in next as 9.5-point favorites over the Las Vegas Raiders.
On the other side of things, the Packers are 2.5-point underdogs against the Lions, while the Jets hold similar underdog odds against the Falcons. The Buccaneers are only favored by a field goal over the Cardinals in Week 13.
Moneylines and Betting Odds for Week 13
The moneyline resembles a similar story, but the Seahawks are -750 over the Vikings, whereas the Rams are -720 over the Panthers. The Chargers hold a -560 line over the Raiders.
Let us now take a look at the betting odds as per FanDuel for all week 13 matchups, along with the predictions.
Green Bay Packers (7-3-1) vs Detroit Lions (7-4)
Both the NFC North rivals are neck and neck in the standings, and while the Packers are just slightly ahead, both teams are currently chasing the Bears at the top of the division. This is a crucial game for both these teams, as neither has been extraordinary this season.
Both teams have been shaky at times this season, but the Lions seem to have the better overall roster. Plus, Jahmyr Gibbs is proving difficult to stop this year.
Kansas City Chiefs (6-5) vs Dallas Cowboys (5-5-1)
This game between the Chiefs and the Cowboys will be very important for both teams with regard to their push for a playoff spot. The Chiefs are on the outside in the AFC, and the Cowboys face the same scenario in the NFC.
Kansas City overcame a tough Colts team last week, but Dallas overcame a 21-point deficit over the Eagles, and the home advantage could favor them in this matchup. Moreover, the Chiefs are struggling quite a bit this season and are lacking offensive rhythm.
Cincinnati Bengals (3-8) vs Baltimore Ravens (6-5)
In all likelihood, Bengals fans will be happy to see the return of Joe Burrow for the Bengals on Thanksgiving Day. If he takes the field against the Ravens on Thursday, it will be a massive boost for Cincinnati despite the loss of Tee Higgins to a concussion.
That said, Burrow may not be in complete footballing form, and the Ravens are currently on top of their game, having won 5 straight and taken control of the division.
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Chicago Bears (8-3) vs Philadelphia Eagles (8-3)
The Bears are on a 4-game win streak and have won 6 of their last 7 games. It finally feels like Caleb Williams and Ben Johnson are clicking, and the results are there for everyone to see.
The Eagles have also won 4 of their last 5 games, but blew a massive 21-point lead over the Cowboys last week. Also, the offense is showing some cracks, and they need to be sorted quickly.
As good as the Panthers have been so far this season, this game against the Rams should be a tough hurdle to overcome. Not only has Carolina not been consistent enough, but the Rams have done the exact opposite.
Mathew Stafford is playing lights-out football, and both sides of the ball are clicking. The Rams currently hold the top seed in the NFC and are on a 6-game win streak.
Rams Offensive Grades through Week 12, according to @PFF: – 1st in Offensive Grade (91.7) – 1st in Passing Grade (93.1) – 1st in Run Blocking Grade (88.3) – 2nd in Receiving Grade (86.6) pic.twitter.com/1YWF7ABCTp
Arizona Cardinals (3-8) vs Tampa Bay Buccaneers (6-5)
Tampa Bay started the season very strong, going 6-2 in their first 8 games. However, with Mike Evans out for the season, the Bucs have struggled to win 6-5 after a 3-game losing streak. Luckily for them, they take on the Cardinals, who are still one of the weaker teams in the league.
Jacksonville Jaguars (7-4) vs Tennessee Titans (1-10)
The Jaguars are 3-3 in their last 6 games and have hit a minor slump after a wonderful 4-1 start to the season. That said, they are facing the worst team in the league in the Titans, and this should be an easy win for Jacksonville.
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New Orleans Saints (2-9) vs Miami Dolphins (4-7)
Technically, the Miami Dolphins are still in with a decent shot at making the playoffs, irrespective of how small their chances are. But, they have won games on a trot with wins against the Bills and the Commanders. This week, they take on the struggling New Orleans Saints, and a win here for the Dolphins could give them a massive boost for their upcoming games.
San Francisco 49ers (8-4) vs Cleveland Browns (3-8)
This is a very important game for the 49ers at this point in the season. They are in a 3-way battle in their division with the Rams and the Seahawks, and need to win to keep the pressure on those teams.
The Browns’ defense, led by Myles Garrett, is legit, and we saw what happened to Brock Purdy in the last game against the Panthers. It won’t be easy, but expect the 49ers to come through against a Browns team that still lacks the offense.
The Jets are nearly done for the season and have also traded away two of their top defenders at the trade deadline. The Falcons are not having the best of seasons by any means, but the thought of a few wins to make things interesting should help Atlanta over the line.
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Houston Texans (6-5) vs Indianapolis Colts (8-3)
The Colts will be looking to bounce back quickly after a loss to the Chiefs last week. That’s now 2 losses in their last 4 games, and Indianapolis needs to stack up some wins if they want to challenge for the top seed in the AFC.
Houston, though, has suddenly struck great form and is on a 3-game win streak, despite C.J. Stroud being out for all three games. The Texans’ defense should not be taken lightly, but the slight edge goes to the Colts just because of how well they have played thus far.
J.J. McCarthy and the Vikings are struggling massively this season, and they have a tough task against the Jaxon Smith-Njigba-led Seattle Seahawks. The Seahawks will come out firing on all cylinders, especially as the NFC West is in a 3-way battle. With the way both teams have been playing, this should be a comfortable win for Seattle.
Prediction: Seattle Seahawks to win and cover the spread.
Buffalo Bills (7-4) vs Pittsburgh Steelers (6-5)
Buffalo needs to win this game to keep some pressure on the Patriots at the top of the AFC East, whereas the Steelers need to do the same to keep pace with the Ravens in the AFC North.
Both teams have been inconsistent of late, and there is no clear winner on paper. Josh Allen’s rich form, coupled with James Cook’s emergence from the backfield, gives the edge to the Bills.
Las Vegas Raiders (2-9) vs Los Angeles Chargers (7-4)
Coming off their bye week, the Chargers should be ready to go. The Raiders shouldn’t pose too many problems, and Los Angeles will know that a win will help them keep the Chiefs at bay in the AFC West. Vegas is having another down season yet again.
Denver Broncos (9-2) vs Washington Commanders (3-8)
Things couldn’t be any more different between these two teams at the moment. Denver is currently enjoying an 8-game win streak and is the number 2 seed in the AFC. Washington, on the other hand, is on a 6-game losing streak.
The Commanders have gone from making the NFC Championship game last season to nearly being out of the postseason contention in just 12 weeks.
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New York Giants (2-10) vs New England Patriots (10-2)
A complete mismatch on paper with two teams trending in opposite directions. The Giants already became the first team to officially be out of the playoffs for the 2025-26 NFL season with their loss to the Lions last week. With nothing but pride to play for, they could be dangerous.
However, New England is the current number one seed in the AFC, and another win will only help them keep the other teams at bay. Ideally, the Patriots should come through with an easy win.
I am a content writer for the NFL team, and joined The Playoffs after working with Sportskeeda and NFL Analysis as an NFL writer. After starting my professional career as a French-to-English translator, working as a content writer is a new adventure for me. I started out in the sports media field for two main reasons: my love for sports in general, especially the NFL, NBA, and Tennis, as well as my passion for writing. The best part of this job is that I get to write a variety of pieces with the freedom to explore content from various angles. It also enables me to stay up to date with the sporting world, which otherwise can be difficult to do in the day-to-day grind. In a world full of chaos, sports unite and entertain like nothing else!
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