Manchester City and Napoli are set to meet at the Etihad in the 2025-26 Champions League opener. This would mark Kevin De Bruyne’s first return against his former club. City are coming fresh from a derby win over Manchester United. They will seek consistency after a poor European run last season.
Pep Guardiola’s side are boasting an unbeaten home record in League Phase games. Napoli, the reigning Serie A champions under Antonio Conte, have started their season strongly with three wins, boosted by new signings De Bruyne and Rasmus Hojlund. However, notably, they have never beaten an English side away.
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— Official SSC Napoli (@en_sscnapoli) September 18, 2025
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Here are the Odds to first goalscorer and anytime goalscorer for Manchester City vs Napoli (via FanDuel):
| Player | Team | First Goal Scorer Odds | To Score Odds |
| Erling Haaland | Man City | +280 | -130 |
| Tijjani Reijnders | Man City | +490 | +150 |
| Phil Foden | Man City | +700 | +220 |
| Lorenzo Lucca | Napoli | +750 | +250 |
| Rasmus Hojlund | Napoli | +950 | +340 |
| Guiseppe Ambrosino | Napoli | +1000 | +380 |
Erling Haaland headlines the market at +280 to score first and –130 anytime, reflecting his dominance as Manchester City’s top striker. Tijjani Reijnders (+490/+150) follows as a secondary option with attacking threat from midfield, while Phil Foden (+700/+220) adds creativity and finishing. For Napoli, Lorenzo Lucca (+750/+250) leads their chances, with Rasmus Højlund (+950/+340) and Giuseppe Ambrosino (+1000/+380) priced as longer-shot goal scorers.
Also Read: Manchester City vs Napoli Preview, Betting Odds and Predictions – 18/08/25
Here are the odds to assist anytime for Manchester City vs Napoli (via BetMGM):
| Player | Team | Moneyline |
| Jeremy Doku | Man City | +280 |
| Savinho | Man City | +290 |
| Phil Foden | Man City | +320 |
| Kevin De Bruyne | Napoli | +380 |
| Mateo Politano | Napoli | +600 |
| Leonardo Spinazzola | Napoli | +625 |
Jeremy Doku leads the assist market at +280, with his dribbling and creativity making him a constant supply line for Manchester City. Savinho (+290) is close behind, offering pace and flair in wide areas, while Phil Foden (+320) adds another strong creative option. For Napoli, Kevin De Bruyne (+380) – listed unusually with them – joins Mateo Politano (+600) and Leonardo Spinazzola (+625) as longer-shot providers.
Erling Haaland is someone who cannot be ignored in a match. The chances that he will score is a major one. Hence, the odds at -165 seems justified.
Also Read: Manchester City vs Napoli: Top Over/Under Odds, Betting Tips and More
Taking the pre-season and Club World Cup into account, Phil Foden has already registered a number of goals to his name early in this season. Hence, the odds at +138 for him to either score or assist seems like a good bet.
Kevin De Bruyne may have moved to another club but his knack for contributing to a goal has not diminished at all. He has already fired up for Napoli this early in the season. He could imitate that performance in his first return to the Etihad Stadium.
Odds via FanDuel.
| Player | Team | Moneyline |
| Erling Haaland | Man City | +390 |
| Tijjani Reijnders | Man City | +800 |
| Lorenzo Luca | Napoli | +1700 |
| Rasmus Hojlund | Napoli | +2700 |
Erling Haaland leads the multi-goal market at +390, reflecting his regular ability to deliver braces for Manchester City. Tijjani Reijnders follows at +800, offering a midfield scoring threat but with less consistency. For Napoli, Lorenzo Lucca (+1700) carries their best chance of striking twice, while Rasmus Højlund (+2700) is considered more of a long-shot option.
soccer Football writer at The Playoffs. I’ve been obsessed with the beautiful game since I was a kid.. Eventually, I realized I could combine my passion for writing with my love for football, and I’ve never looked back. My favorite part of the job is everything—when you’re doing what you love, even a late-night deadline feels like extra time in a thrilling cup final. Lastly, Lionel Messi is the GOAT.
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