Detroit Lions coach Dan Campbell celebrates a touchdown scored by running back Jahmyr Gibbs during the first half of the NFC championship game vs. the San Francisco 49ers at Levi's Stadium in Santa Clara, California, on Sunday, Jan. 28, 2024.

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Week 17 Monday Night Football Lions vs. 49ers Injury Report: Who’s in, Who’s out?

Lions vs. 49ers Week 17 injury updates

The stage is set for the final Monday Night Football game of the 2024 NFL regular season. It’s a rematch of last year’s NFC Championship Game, but this time, the stakes couldn’t be more different.

The Detroit Lions, sitting pretty at 13-2, are playoff-bound and still gunning for the No. 1 seed in the NFC. Meanwhile, the San Francisco 49ers are staring at a forgettable 6-9 record, eliminated from postseason contention. Sure, the Lions have their sights set on bigger prizes, but this matchup still matters—call it redemption for last year’s heartbreak.

If the Vikings beat the Packers in Week 17 — before Detroit’s MNF game vs. the 49ers — the Lions can’t clinch the division or the No. 1 seed until they play Minnesota in Week 18.

Don’t expect Dan Campbell to rest his starters.

“We’re bringing everything we’ve got to this game.” pic.twitter.com/VgJo9otoDz
— Colton Pouncy (@colton_pouncy) December 23, 2024

The injuries, though? Those could define the night. Let’s cut the noise and focus on what really matters: who’s in, who’s out, and what that means for Monday’s game.

Lions vs. 49ers Injury Report

Game Time: Monday, Dec. 30, 8:15 p.m. ET

Detroit Lions Injuries

David Montgomery (RB): Did Not Participate (Knee) – OUT
Kalif Raymond (WR): Full Participation – OUT
Jalen Reeves-Maybin (LB): Full Participation – QUESTIONABLE
Terrion Arnold (CB): Full Participation – (-)
Graham Glasgow (OL): Full Participation – (-)

Key Absences:
The Lions face a significant challenge with star running back David Montgomery ruled out. His absence puts more pressure on rookie Jahmyr Gibbs, who will carry the ground game solo against a struggling 49ers rush defense. Kalif Raymond’s unavailability further limits Detroit’s offensive depth.

San Francisco 49ers Injuries

Aaron Banks (G): Did Not Participate (Knee) – OUT
Robert Beal Jr. (DE): Did Not Participate (Ankle) – OUT
Spencer Burford (G): Did Not Participate (Calf) – OUT
Dre Greenlaw (LB): Did Not Participate (Calf) – OUT
Colton McKivitz (OT): Limited Participation (Knee) – QUESTIONABLE
Isaac Guerendo (RB): Full Participation – (-)
Nick Bosa (DE): Full Participation – (-)

Key Absences:
San Francisco’s offensive line is in shambles, with multiple key starters, including Aaron Banks and Spencer Burford, ruled out. Brock Purdy could face relentless pressure against Detroit’s blitz-heavy defense. The absence of Dre Greenlaw further weakens the 49ers’ defensive stability.

Key storylines to watch in Lions vs. 49ers

Jahmyr Gibbs stepping into the spotlight

With David Montgomery sidelined, all eyes are on rookie Jahmyr Gibbs. Can he continue his explosive form and carry the Lions’ offense? His solo performances have been stellar, averaging over 130 scrimmage yards per game without Montgomery. Against a banged-up 49ers defense that has struggled to stop the run, this could be a breakout moment for the young back.

Can Brock Purdy survive the Lions’ blitz?

The 49ers’ offensive line is a disaster. Missing starters across the board, they’ll have to protect Purdy against one of the most aggressive blitzing teams in the league. The Lions have been relentless, pressuring QBs on 41.1% of dropbacks since Week 7. Purdy has struggled under pressure, and with his protection crumbling, this could be a rough night for San Francisco.

Deebo Samuel’s resurgence

Deebo Samuel looked like a shell of himself midseason, but last week’s performance against the Dolphins (96 yards, one touchdown) was a glimpse of the old Deebo. With the Lions’ 27th-ranked pass defense and a depleted secondary, this could be the game where he re-establishes himself as San Francisco’s go-to playmaker.

Detroit Lions Injury Report

Player	Position	Injury	Thu	Fri	Sat	Game Status
David Montgomery	RB	Knee	DNP	DNP	DNP	OUT
Kalif Raymond	WR	Foot	FP	FP	FP	OUT
Jalen Reeves-Maybin	LB	Neck	FP	FP	FP	QUESTIONABLE
Terrion Arnold	CB	Illness	DNP	LP	FP	(-)
Graham Glasgow	OL	Knee	FP	FP	FP	(-)

San Francisco 49ers Injury Report

Player	Position	Injury	Thu	Fri	Sat	Game Status
Aaron Banks	G	Knee	DNP	DNP	DNP	OUT
Robert Beal Jr.	DE	Ankle	DNP	DNP	DNP	OUT
Spencer Burford	G	Calf	DNP	DNP	DNP	OUT
Dre Greenlaw	LB	Calf	DNP	DNP	DNP	OUT
Ji’Ayir Brown	SAF	Ankle	LP	LP	DNP	QUESTIONABLE
Leonard Floyd	DE	Shoulder	LP	LP	FP	(-)
Isaac Guerendo	RB	Foot, Hamstring	LP	LP	FP	(-)
Colton McKivitz	OT	Knee	LP	DNP	DNP	QUESTIONABLE
Tatum Bethune	LB	Knee	FP	FP	FP	QUESTIONABLE
Nick Bosa	DE	Hip, Oblique	FP	FP	FP	(-)
Jordan Elliott	DT	Knee	FP	FP	FP	(-)
Talanoa Hufanga	SAF	Wrist	FP	FP	FP	(-)
Dee Winters	LB	Chest	FP	FP	FP	(-)
Kyle Juszczyk	FB	Illness		DNP	FP	(-)
Charvarius Ward	CB	Not injury Related – Personal Matter			DNP	OUT

How to Watch Lions vs. 49ers

Location: Levi’s Stadium, Santa Clara, California
Date: Monday, Dec. 30, 2024
Time: 8:15 p.m. ET
TV Channel: ABC/ESPN
Streaming: Fubo, Sling

Image: Imagn Images

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Natasha Bose

I write about sports because, well, it brings in the big bucks! I’m not some lifelong analyst or stats guru, truth being told, you’ve probably never heard of me!—I just know how to research, write, and make things sound good. That’s the job!
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