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Real Madrid vs Villarreal Preview, Betting Odds and Predictions – 04/10/25

Moumita Dutta

Real Madrid will look to bounce back in La Liga when they host Villarreal at the Santiago Bernabeu on Saturday evening. After a blistering start to the campaign, Los Blancos stumbled last weekend. They are now aiming for an immediate response.

The visitors, Villarreal, have enjoyed a strong opening to the season themselves. They’re arriving with just two points behind Madrid in the table. With both sides in the top three, the encounter promises to be one of the standout fixtures of the weekend.

Real Madrid vs Villarreal Best Bets

BetsStatusMoneyline
Total GoalsOver 3.5-102
Total ShotsOver 28.5-114
Total Shots on TargetOver 10.5Evens
Total CornersUnder 9.5Evens
Real Madrid Goalkeeper Total SavesOver 2.5+115
Villarreal Goalkeeper Total SavesOver 5.5+170
Total CardsUnder 4.5-182
Penalties in the GameYes+136

Real Madrid vs Villarreal Preview

Real Madrid

Real Madrid suffered a heavy 5-2 defeat to Atletico Madrid in their last league outing. That ended a six-match winning streak. Still, Xabi Alonso’s men remain second in La Liga and have also collected two wins in the Champions League. Injuries continue to limit defensive options. 

They are missing Dani Carvajal, Trent Alexander-Arnold, Antonio Rudiger, and Ferland Mendy. Eder Militao is expected to return, and Alonso may switch to a back three. Aurelien Tchouameni could drop deeper. In attack, Jude Bellingham should start behind Kylian Mbappe and Vinicius Junior. Meanwhile Eduardo Camavinga and Federico Valverde are also likely to feature.

Also Read: Thomas Tuchel Names England Squad for October Games: Who Missed and Who Made the Cut?

Villarreal

Villarreal come into this clash in excellent form. They’ve won their last three league games against Osasuna, Sevilla, and Athletic Bilbao. They also drew 2-2 against Juventus in midweek Champions League action. Injuries remain an issue for Marcelino, with Juan Foyth, Willy Kambwala, Logan Costa, and Pau Cabanes ruled out.

Meanwhile Gerard Moreno and Ayoze Perez are also facing late fitness tests. Georges Mikautadze should continue in the frontline and could be joined by Nicolas Pepe. Several changes are expected from midweek, with Luiz Junior likely to return in goal and Thomas Partey, Sergi Cardona, and Alberto Moleiro pushing for starts.

Real Madrid vs Villarreal Over/ Under Predictions

Total Goals Over 3.5 @ -102 as per BetMGM:

With both sides firing, a high scoring encounter is expected in this game. Especially given Real Madrid’s attacking potential. Madrid have already shown goal-scoring prowess this season. They’ve racked up six consecutive league wins before a heavy derby loss. Real’s ability to break Villarreal’s lines along with vulnerabilities in the Yellow Submarine’s defense and vice versa, makes 3-1 or 3-2 wins for Real Madrid plausible outcomes. 

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Real Madrid vs Villarreal Player Picks

Kylian Mbappe to score anytime @ -195 as per FanDuel:

Backing Kylian Mbappe to score at any time is well supported by his current spectacular form and historical trends. He leads Real Madrid in scoring this season with 8 La Liga goals.  His attacking prowess and regular involvement in Madrid’s decisive moments make his pick at -195 odds justified. Given Madrid’s history of strong performances at home and his capacity to exploit gaps, betting on him to find the net seems logical.

Gonzalo Garcia to either score or assist anytime @ -150 as per FanDuel:

While not as headline-making as Mbappe, Gonzalo Garcia’s creative role means he’s capable of either a goal or assist. He already registered an assist in Madrid’s last game against Kairat in the Champions League. In a match where Madrid may push forward heavily, Garcia’s involvement in build-up play and chance creation increases his upside for a goal or assist.

Real Madrid vs Villarreal Predictions

PicksMoneyline
Kylian Mbappe to score first+250
Vinicius Jr to score anytime+100
Jude Bellingham to assist anytime+165
Franco Mastantuono to either score or assist-140
Renato Veiga to see a card+185
Renato Veiga to commit one foul or more-210

Also Read: Philadelphia 76ers’ Joel Embiid Thinks England will ‘Choke Again’ in 2026 World Cup 

Madrid beat Villarreal twice last season in La Liga. They certainly possess the quality to dominate possession and break the opposition repeatedly. The 5-2 defeat in the Madrid derby was a blip. Overall, Madrid have shown consistency, and Villarreal’s injury concerns weaken their depth. 

Final Prediction: Real Madrid 3-1 Villarreal

Madrid can dominate at home, especially with their attacking firepower. However, the absence of some key players at the back may cause problems. Similarly, Villarreal’s defensive frailties mixed with their current form, it may be a tough but comfortable 3-1 win for Real Madrid.

When and where is the Real Madrid vs Villarreal game?

The Real Madrid vs Villarreal La Liga clash is on October 4, 2025, at the Santiago Bernabeu Stadium, Madrid, Spain.

What are the BetMGM betting odds for the Real Madrid vs Villarreal game?

Real Madrid are favorites to win with a moneyline at -225, to draw at +400 and for Villarreal to win at +525.

Name some key player prop bets for the game from BetMGM

Vinicius Junior total shots: 4+ at -550
Kylian Mbappe total shots on target: 2+ at -500
Arda Guler assist: +240

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Football writer at The Playoffs. I’ve been obsessed with the beautiful game since I was a kid.. Eventually, I realized I could combine my passion for writing with my love for football, and I’ve never looked back. My favorite part of the job is everything—when you’re doing what you love, even a late-night deadline feels like extra time in a thrilling cup final. Lastly, Lionel Messi is the GOAT.

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