Philadelphia Eagles vs Los Angeles Rams Preview, Betting Odds, and Predictions – NFL 2025-26 Season Week 3

The Los Angeles Rams travel on the road to take on the Philadelphia Eagles for Week 3 matchup, at Lincoln Financial Field. Both teams have started out the season strong, remaining undefeated, at 2-0, and this will be a rematch of last season’s NFC’s divisional round matchup, where the Rams came close to knocking off the Eagles.

The stakes does not get higher than this as both teams will try to remain undefeated as one of them have a take the loss home if they do. The Rams have all the pieces in place, but is it enough to knockoff the reigning defending champs? We’ll find out soon enough.

Recommended Bets	FanDuel	BetMGM
Saquon Barkley Anytime Touchdown Scorer	-145	-160
Jalen Hurts over 26.5 passing attempts	-118	-145
Jalen Hurts under 0.5 interceptions	-160	-220

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Analysis and Rationale

Saquon Barkley is a prime anytime TD scorer against the Rams, having rushed for TDs in both Week 1 and Week 2, against the Cowboys and the Chiefs respectively. LA’s run defense could be vulnerable to Philly’s elite O-line. Barkley’s 2.0 YPC average and red-zone role with Jalen Hurts boost his scoring odds in this clash.

Jalen Hurts exceeding 26.5 passing attempts is a strong bet as he’s averaged 22.5 attempts through two games (23 vs Cowboys, 22 vs. Chiefs), but LA’s pass defense is elite which could be troublesome, forcing QBs into higher volume to sustain drives. Philly’s run-heavy scheme may shift with a close matchup, pushing Hurts past his usual averages.

Jalen Hurts throwing under 0.5 interceptions is a solid bet as he’s throw zero picks through two games in 2025, completing majority of his passes. LA’s defense has struggled to force turnovers this season, favoring Hurts’ clean play in this Week 3 clash.

Philadelphia Eagles vs L.A. Rams Preview

Both the Philadelphia Eagles and Los Angeles Rams enter Week 3 undefeated, setting the stage for a high-stakes clash at Lincoln Financial Field. The Eagles lean on Saquon Barkley’s punishing ground game and Jalen Hurts’ dual-threat versatility, while the Rams counter with Matthew Stafford’s sharp passing and a stingy run defense.

With both teams 2-0, this matchup feels more like January than September, a rematch of last season’s playoff thriller, and a potential NFC playoff preview.

Divisional round rematch. pic.twitter.com/cl82sDpM8i
— Los Angeles Rams (@RamsNFL) September 17, 2025

Philadelphia Eagles Best Bets – Over/Under and Player Bets

Here are over/under and best player bets for the Philadelphia Eagles, according to BetMGM

Over/Under Bets	Over	Under
Jalen Hurts Passing Yards	198.5 (-115)	198.5 (-115)
A.J. Brown Receiving Yards	61.5 (-115)	61.5 (-115)
Saquon Barkley Rushing Yards	85.5 (-118)	85.5 (-110)

Philadelphia Eagles Best Player Bets

Below are some of the best player bets for the Philadelphia Eagles, as per BetMGM

Saquon Barkley Anytime TD scorer: -160
Jalen Hurts under 0.5 interceptions: -220
A.J. Brown over 4.5 receptions made: -140

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Los Angeles Rams Best Bets – Over/Under and Player Bets

Here are over/under and best player bets for the Los Angeles Rams, as per BetMGM

Over/Under Bets	Over	Under
Matthew Stafford Passing yards	229.5 (-115)	229.5 (-115)
Puka Nacua Receiving Yards	78.5 (-130)	78.5 (+100)
Kyren Williams Rushing Yards	64.5 (-110)	64.5 (-118)

Los Angeles Rams Best Player Bets

Below are some of the best player bets for the L.A. Rams, according to BetMGM

Matthew Stafford to throw over 0.5 interceptions: -120
Puka Nacua over 6.5 receptions made: -130
Kyren William Anytime TD scorer: -105

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Eagles vs Rams Prediction for Week 3 Matchup of the 2025-26 NFL Season

The Eagles are slightly favored to win the matchup and rightly so. Their dominant run game and stout defense should control the tempo, while Jalen Hurts looks to exploit L.A.’s secondary using A.J. Brown as their weapon. The Rams, led by Stafford and a revamped offense, should be able to keep it close, but Philly’s home streak and playoff pedigree give them the edge.

Prediction: Eagles win the game 27-23

Ready for the Rams @Verizon | #FlyEaglesFly pic.twitter.com/kddwo4rgKM
— Philadelphia Eagles (@Eagles) September 17, 2025

Eagles vs Rams Betting Odds and Spread

The spread and the moneyline show that the Eagles are the slight favorites to win this matchup against the Rams, according to BetMGM

Teams	Spread	Total Points	Moneyline
Rams	+3.5 (-115)	44.5 (-110)	+155
Eagles	-3.5 (-105)	44.5 (-110)	-190

(According to BetMGM: BetMGM offers exclusive promo codes, bonus deals and accurate odds for users upon signing up. Use BetMGM to ace your betting game in all sports!)

FAQs

Who is favored to win the Eagles vs Rams game?
Eagles are slight favorite with a -3.5 spread and -190 moneyline

What are the best player bets for this matchup?
Barkley anytime TD (-160), Hurts under 0.5 interceptions (-220), Nacua over 6.5 receptions (-130)

What is the predicted score for the Eagles vs Rams game?
Eagles are predicted to win 27-23 over the Rams.

Eric Divakaran

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I cover the National Football League and things cannot get better than that. I always dreamed to play football or basketball professionally since I’m built like a Running Back. But now that I can’t, since I’m technically in the “Unc” age, I thought why not pick a career in sports industry? So here I am, doing what I love, and hoping that the Commanders win the Super Bowl. I give love to players when it’s due, but can be critical about their performances at the same time. Enough about me, now let my articles do all the talking.