Last week in the NFL, the favorites went 9-7 in the ATS record, which means there were plenty of underdog wins as well. As we get to the business end of the regular season, teams making a push for the playoffs have a lot on the line, while those that have missed out may be looking to start some backups and rookies.
Injuries have also played a massive role this season, and now, with 15 weeks already in the books, several teams have been hit with key players out for the season. And with that out of the way, let us take a look at the NFL Week 16 ATS picks.
Below is a list of our Week 16 ATS picks along with the line (sourced via FanDuel).
| Matchup | Pick |
|---|---|
| Rams at Seahawks | Rams +1.5 (-112) |
| Eagles at Commanders | Eagles -6.5 (-110) |
| Packers at Bears | Bears +1.5 (-120) |
| Chargers at Cowboys | Chargers +2.5 (-112) |
| Vikings at Giants | Vikings -2.5 (-122) |
| Bills at Browns | Browns +10.5 (+100) |
| Jets at Saints | Saints -4.5 (-110) |
| Buccaneers at Panthers | Buccaneers -3 (-110) |
| Bengals at Dolphins | Bengals -4.5 (-110) |
| Chiefs at Titans | Titans +3 (-110) |
| Jaguars at Broncos | Broncos -3 (-115) |
| Falcons at Cardinals | Falcons -2.5 (-115) |
| Steelers at Lions | Lions -6.5 (-120) |
| Raiders at Texans | Texans -14.5 (-104) |
| Patriots at Ravens | Patriots +2.5 (+100) |
| 49ers at Colts | Colts +6.5 (-120) |
This is a matchup between two exceptionally talented football teams at the moment. Both the Rams and the Seahawks have seen great quarterback and receiver play on offense while also having a top 5 scoring defense. That said, the Rams won their previous game in LA a few weeks ago, and with the way Matthew Stafford is playing under center, the Rams have a slight edge.
The Eagles are playing to clinch the NFC East this week against the Commanders. This season has been a forgettable one for the Commanders, starting with injuries to key players, especially quarterback Jayden Daniels. The second-year signal caller is out for the season, and Philly is coming off its get-right game against the Raiders.
It’s taken quite a few years, but the Bears are looking like a top team once again. Their rivalry with the Packers has always been an exciting one, but now it could take a new turn. Green Bay has been hit with multiple injuries, and none more crushing than that of Micah Parsons. This could be a major factor in the Bears overcoming their opponents.
What’s common between the Chargers and the Cowboys? Both teams have pulled off a rare achievement of defeating the previous year’s Super Bowl teams in back-to-back weeks. But that is pretty much where the comparisons stop this season, as the Chargers are a mid-tier offense backed by a strong run game. The Cowboys are at the bottom of most defensive categories.
The season is over for both teams, with nothing much to look forward to. However, the Vikings have a top 15 scoring defense, while the Giants are in the bottom 5, allowing over 28 points per game.
If you’re looking for a complete guide to the best NFL betting sites, we’ve got you covered
Josh Allen and the Bills are coming off an amazing come-from-behind win over the New England Patriots last week. The morale of the team is high, and they are just one game behind the Patriots in the AFC East now. The Browns are struggling, but Myles Garrett will be looking to notch up the sack record in this game.
Nothing much to say about two teams that have struggled throughout the season. However, the Saints’ play over the last 5 games has improved, having defeated the Panthers twice and the Bucs once, whereas the Jets have suffered heavy defeats in 4 of their last 5 games.
This is a crucial tie as the winner of this matchup will take a one-game lead in the NFC South with just two weeks of regular-season football remaining. Mike Evans returned last week for Tampa, and the Bucs got back to winning ways.
The Dolphins were enjoying a decent little run of 4 wins on the trot until they lost to the Steelers last week. Their playoff hopes are over, and while they played some great football over the last month, rookie QB Quinn Ewers is set to make his first start in the professional league. That could hand the advantage to the Bengals.
The Titans over the Chiefs might not be a popular choice, but with Patrick Mahomes gone for the season and a lack of a quality offense, the Chiefs may just let the remaining games slide. They have already been knocked out of the postseason and are improving little by little.
Both the Broncos and the Jaguars have surprised one and all this season with this turnaround. This game is also a crucial one in the context of the postseason seedings. If Denver wins, Jacksonville’s chance at the number one seed would be gone. Leaving the warmth of Florida to play in Denver’s cold climate at this time of the year could be advantageous for the Broncos.
A matchup between two of the worst teams this season. The Falcons have the better roster, even though they have massively underperformed. Last week’s win over the Bucs was a big one, and with Kirk Cousins commanding the offense, Atlanta is the favorite in this matchup.
Quite an important game with the postseason right around the corner. Both teams need a win, but the Lions more than ever. Detroit’s chances of making the playoffs are hanging by a thread, but their number one scoring offense will be going up against a mid-tier Steelers’ scoring defense. Additionally, there is no official return timeline for T.J. Watt.
Two teams going in opposite directions. The Raiders are 2-12 and on an 8-game losing streak, whereas the Texans are 9-5 and on a 6-game winning streak. They have suffered heavy defeats in 3 of their last 5 games against the Eagles, Chargers, and Cowboys. The way the Texans have improved on offense and with their number-one scoring defense, it’s going to be a tough Sunday afternoon for Vegas.
The Patriots taking on the Ravens is yet another marquee matchup this week. New England needs a win to keep pressure on Denver for the one seed in the AFC, while Baltimore needs a win for a chance at winning the AFC North.
The Patriots just had a 10-game winning streak snapped by the Bills last week, but even then, Mike Vrabel’s team is a force to deal with. Quarterback Drake Maye is in the running for the MVP.
It’s a game between a team that has won 4 in a row (49ers), and a team that has lost 4 in a row (Colts). The momentum in this clash is certainly with the 49ers, but interestingly, even with Phillip Rivers under center after a hiatus of 5 years, the Colts narrowly lost to the Seahawks last week. Both teams are similar in scoring defense, but the Colts are still one of the better offensive teams.
The above odds are sourced from FanDuel. Use FanDuel to ace your betting game in all sports!
Mandatory Credit: Kevin Ng-Imagn Images
nfl I am a content writer for the NFL team, and joined The Playoffs after working with Sportskeeda and NFL Analysis as an NFL writer. After starting my professional career as a French-to-English translator, working as a content writer is a new adventure for me. I started out in the sports media field for two main reasons: my love for sports in general, especially the NFL, NBA, and Tennis, as well as my passion for writing. The best part of this job is that I get to write a variety of pieces with the freedom to explore content from various angles. It also enables me to stay up to date with the sporting world, which otherwise can be difficult to do in the day-to-day grind. In a world full of chaos, sports unite and entertain like nothing else!
Read moreWe use cookies for ads and to improve your experience. By continuing on the site, you agree to our Privacy Policy. Read more about it
NFL