The Seahawks who play the colts are the most favored team in Week 15!
It really is crunch time in the 2025-26 NFL regular season. With just 4 weeks of footballing action left until the playoffs, teams are getting ready for the final push. The top teams from both conferences will be looking to continue their form in order to qualify for the postseason as early as possible.
Week 15 will kick off with the Atlanta Falcons hosting the Tampa Bay Buccaneers in a divisional matchup on Thursday Night Football (TNF) before we get ready for a full slate of 14 games on Sunday, followed by the final game of the week on Monday Night Football (MNF).
NFL Week 15 Team Picks
Here are some of the picks worth considering ahead of the full slate of Week 15 games as per the odds on FanDuel.
Los Angeles Rams win and cover the spread (-5.5) against the Detroit Lions: -115
Los Angeles Chargers win against the Kansas City Chiefs: +180
Denver Broncos win against the Green Bay Packers: +116
Tennessee Titans cover the spread (+12.5) against the San Francisco 49ers: -108
The Rams are the top seed in the NFC with a 10-3 record and have been playing well even against tough competition. Detroit, on the other hand, hasn’t looked like the same team from the past couple of seasons and has struggled against the top teams.
The Chargers and the Chiefs are two AFC West teams trending in opposite directions. While Los Angeles just came off a massive win over the Eagles, the Chiefs lost to the Texans and looked completely out of sorts.
The Broncos have won 10 in a row, while the Packers have been less consistent. Moreover, Green Bay could struggle to score against Denver’s top defense, while the atmosphere at Mile High could add to the difficulty.
Although the Titans have lost several games with double-digit margins, Tennessee has shown improvement over the past few weeks. Apart from their Week 14 win over the Browns, three of the Titans’ previous four games have ended in a single-digit margin loss.
In a massive turn of events, the Indianapolis Colts are suddenly underdogs, and a big one that too against the Seattle Seahawks this week. The Seahawks are favored by 13.5 points over the Colts. Other favorites by a big margin are the Jaguars (-12.5) over the Jets, the 49ers (-12.5) over the Titans, and the Eagles (-11.5) over the Raiders.
The closest game predicted this week is the confrontation between the AFC East teams, the Patriots and the Bills, in which the latter are the favorites by a slim 1.5-point margin.
Moneylines and Betting Odds for Week 15
The moneyline shows a similar trend, but the Seahawks are a colossal -1150 over the Colts. The 49ers come in next at -950, while the Jaguars are at -900, with the Eagles a -770 favorite over the Raiders. As you can imagine, the Bills hold just a -180 line over the Patriots.
Let us now take a look at the betting odds as per FanDuel for all week 15 matchups, along with the predictions.
Atlanta Falcons (4-9) vs Tampa Bay Buccaneers (7-6)
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New York Jets (3-10) vs Jacksonville Jaguars (9-4)
“I’m dying for Buffalo to play a great game… I’m begging Buffalo. I’m begging Josh Allen. Begging him. I know you’re not playing as well as Drake Maye… Give us a game.”@kevinwildes wants his Patriots to be tested this weekend: pic.twitter.com/kRYgKsW1bh
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"This is a panic move to try to do something THIS YEAR."@PriscoCBS on the Colts signing QB Philip Rivers to their practice squad. pic.twitter.com/MC7uudMUuj
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I am a content writer for the NFL team, and joined The Playoffs after working with Sportskeeda and NFL Analysis as an NFL writer. After starting my professional career as a French-to-English translator, working as a content writer is a new adventure for me. I started out in the sports media field for two main reasons: my love for sports in general, especially the NFL, NBA, and Tennis, as well as my passion for writing. The best part of this job is that I get to write a variety of pieces with the freedom to explore content from various angles. It also enables me to stay up to date with the sporting world, which otherwise can be difficult to do in the day-to-day grind. In a world full of chaos, sports unite and entertain like nothing else!
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