Minnesota Timberwolves vs. Indiana Pacers Predictions, Odds and Best Bets For 10/26

The Minnesota Timberwolves return home at 1–1 after edging Portland behind Anthony Edwards’ 41 points, then falling to the Lakers 128–110 as defensive lapses and Rudy Gobert’s struggles at the rim proved costly. Anthony Edwards has been electric, averaging 36 points through two games, but Minnesota ranks near the bottom defensively.

The Indiana Pacers, meanwhile, are 0–2 and reeling from Tyrese Haliburton’s season-ending injury. Despite Bennedict Mathurin’s scoring bursts and Pascal Siakam’s steady play, injuries and depth issues have left Indiana vulnerable on both ends.

Game details

When: Sunday, October 26, 2025
Time: 07:00 pm ET
Venue: Target Center, Minneapolis
TV: ESPN
Live stream: Fubo

Recommended Bets and Updated Odds

Bet Type	Selection	FanDuel	BetMGM
Winning Margin	Minnesota Timberwolves by 1–5	+500	+600
Total Points	Minnesota Timberwolves Over 120.5	-115	-115
Total Points	Indiana Pacers Over 108.5	-104	+105

Analysis and Rationale

The Indiana Pacers enters this matchup short-handed, already missing Tyrese Haliburton and several rotation guards, with the added concern of Bennedict Mathurin’s health after he exited against Memphis. That leaves Pascal Siakam as the primary scoring option, supported by Aaron Nesmith, but the Pacers’ depth is stretched thin.

Their offense has shown flashes, yet sustaining production without reliable ball-handlers is a major challenge. Minnesota, meanwhile, returns home after splitting its first two games. Anthony Edwards has been explosive, averaging 36 points, while Julius Randle adds steady inside-out scoring. The Timberwolves’ defense has been shaky, but their offensive firepower and healthier roster give them a clear advantage, especially against a Pacers team struggling to keep pace on both ends.

Anthony Edwards tonight:

31 Points
5 Assists
4 Rebounds
11/19 FGM
3/6 3PM
35 Minutes pic.twitter.com/GyPtrBilAn
— Hoop Central (@TheHoopCentral) October 25, 2025

Minnesota Timberwolves vs. Indiana Pacers Prediction

The Minnesota Timberwolves should look to establish control early through Anthony Edwards’ scoring bursts and Julius Randle’s inside-out presence, while tightening up defensively after ranking near the bottom through two games.

Rudy Gobert’s rim protection remains a swing factor, but Minnesota’s depth and home opener energy give them the edge. Indiana, missing Tyrese Haliburton and potentially Bennedict Mathurin, will lean heavily on Pascal Siakam to keep them competitive. Without reliable guard play, sustaining offense looks difficult against Minnesota’s firepower.

Prediction: Minnesota Timberwolves to win

Minnesota Timberwolves vs. Indiana Pacers Betting Odds and Spread

Bet Type	Minnesota Timberwolves	Indiana Pacers
Moneyline	-700	+500
Spread	-12.5 (−110)	+12.5 (−110)
Total	Under 228.5 (−115)	Over 228.5 (−105)

Minnesota Timberwolves vs. Indiana Pacers Best Bets

Here are the over/under and best player bets for the Minnesota Timberwolves, and the Indiana Pacers, according to FanDuel.

Minnesota Timberwolves Over/Under Odds

Bet Type	Selection	Odds
Player Points	Anthony Edwards 20+ Points	-1100
Player Points	Julius Randle 20+ Points	-162
Three Pointers	Donte DiVincenzo 3+	-136

Minnesota Timberwolves Best Player Bets

Jaden McDaniels 15+ Points: +540
Julius Randle 4+ Assists: -400
Anthony Edwards 6+ Assists: +146

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Indiana Pacers Over/Under Odds

Bet Type	Selection	Odds
Player Points	Pascal Siakam 20+ Points	-230
Player Points	Obi Toppin 15+ Points	-106
Player Assists	Pascal Siakam 6+ Assists	+200

Indiana Pacers Best Player Bets

Obi Toppin 3+ Threes: +190
Pascal Siakam Double-Double: +300
Obi Toppin 6+ Rebounds: +112

The odds given above are sourced from FanDuel. Use FanDuel to ace your betting game across all sports.

FAQs

Who’s favored to win?

Minnesota is a heavy favorite at -700 on the moneyline, while Indiana sits at +500. Oddsmakers expect the Timberwolves’ home opener energy and healthier roster to overwhelm a shorthanded Pacers squad.

What’s the spread telling us?

The Timberwolves are laying -12.5 (-110), with Indiana at +12.5 (-110). That’s a big number, signaling bookmakers expect Minnesota not just to win, but to control the game comfortably against a Pacers team missing multiple guards and possibly Mathurin.

What are Anthony Edwards’ odds tonight?

Anthony Edwards is lined at 20+ points (-1100) and 6+ assists (+146)