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Lions vs Steelers Predictions, Odds and Best Bets For Week 16 of the 2025-26 NFL Season

Devavrat Kulkarni

Lions vs Steelers Predictions, Odds and Best Bets For Week 16 of the 2025-26 NFL Season

The Steelers head over to Detroit for a clash against the Lions in this Week 16 matchup. Both teams are in the running for a playoff berth; however, the Lions have the more difficult task on their hands. It is a must-win for Detroit, while a win for the Steelers will ensure they remain on top of the AFC North, at least for one more week. 

Detroit is currently 8-6, but is third in the NFC North behind the Bears and Packers. Meanwhile, the Steelers hold the top spot in their division, but the Ravens are right on their tails. There is a lot to play for in this exciting matchup.  

Game Details:

  • Time: 4:25 p.m. ET
  • Date: Sunday, December 21, 2025
  • Location: Ford Field, Detroit, Michigan
  • TV Channel: CBS
  • Streaming: Paramount+, NFL Sunday Ticket on YouTube, NFL+

Recommended bets and updated odds

Recommended BetsFanDuelBetMGM
Jared Goff Over 1.5 TD passes-215-220
Jahmyr Gibbs Anytime TD scorer-280-286
Total Points Over 51.5-110-112

Analysis and Rationale

Lions quarterback Jared Goff has been quite consistent throughout the season in the red zone. He has thrown 29 touchdowns in 14 games and is averaging slightly above 2 touchdown passes per game. Goff has 6 in his last 3 games, and the Lions’ high-tempo offense provides him with plenty of chances to find the end zone. 

Running back Jahmyr Gibbs is having one of his finest seasons this year, both in terms of rushing yards and finding the endzone. In fact, Gibbs has already scored 13 touchdowns on the ground and added another 3 via receptions, giving him a total of 16 touchdowns in just 14 games. 

This game will most likely come down to the Lions’ high-tempo offense against the Steelers’ defense. Detroit leads the league in scoring with an average of just over 30 points per game, and while Pittsburgh’s scoring defense is allowing a little over 23 points a game, the Lions are an offensive juggernaut. 

On the other side of the ball, the Steelers could also score plenty of points themselves, given that Detroit has a severely banged up secondary at the moment. 

Lions vs Steelers Prediction

This is a classic case of a high-flying Lions’ offense taking on one of the better NFL defenses of the Steelers. There is a high probability of T.J. Watt missing his second game in a row, and that will be a massive boost for Detroit. 

The Lions’ defense has struggled this season mainly due to injuries, especially in the secondary. Unfortunately, though, Pittsburgh doesn’t have the offense to take complete advantage of the situation.

Prediction: Detroit Lions to win.  

Week 16 Lions vs Steelers Betting Odds and Spread

The moneyline and spread show the Detroit Lions are the favorites in this matchup against the Pittsburgh Steelers. (Sourced from FanDuel)

MoneylineSpreadTotal Points
Detroit Lions-320-6.5 (-120)O 51.5 (-110)
Pittsburgh Steelers+260+6.5 (-102)U 51.5 (-110)

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Lions vs Steelers Best Bets

Here are the over/under and best player bets for the Detroit Lions and the Pittsburgh Steelers, as per FanDuel.

Detroit Lions Over/Under Odds

Below are some of the best over/under bets for the Detroit Lions.

Over/ Under BetsOver Under
Jared Goff Passing Attempts 32.5 (-120)32.5 (-108)
Amon-Ra St. Brown Total Receptions7.5 (+110)7.5 (-146)
Jahmyr Gibbs Rush Attempts14.5 (-118)14.5 (-112)

Detroit Lions Best Player Bets

Below are some of the best player bets for the Detroit Lions.

  • Jared Goff Over 264.5 Passing Yards: -114
  • Jameson Williams Over 82.5 Receiving Yards: -114
  • Jahmyr Gibbs Anytime TD scorer: -280

If you’re looking for a complete guide to the best NFL betting sites, we’ve got you covered 

Pittsburgh Steelers Over/Under Odds

Below are some of the best over/under bets for the Pittsburgh Steelers.

Over/ Under BetsOver Under
Aaron Rodgers Pass Attempts32.5 (-108)32.5 (-120)
DK Metcalf Total Receptions4.5 (-106)4.5 (-125)
Jaylen Warren Rush Attempts10.5 (+100)10.5 (-132)

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Pittsburgh Steelers Best Player Bets

Below are some of the best player bets for the Pittsburgh Steelers.

  • Aaron Rodgers Under 230.5 Passing Yards: -114
  • Kenneth Gainwell Over 27.5 Receiving Yards: -114
  • Aaron Rodgers Under 1.5 Passing Touchdowns: -132

The above odds are sourced from FanDuel. Use FanDuel to ace your betting game in all sports!

FAQs

What is the over/under for total points for the Lions vs Steelers game?

The over/under for total points in the Lions vs Steelers game is set at 51.5.

What is the point spread for the Lions vs Steelers game?

The Lions come into the game as 6.5-point favorites over the Steelers.

What is the moneyline for the Lions vs Steelers game?

The Lions are the favorites with a moneyline of -320, while the Raiders are the underdogs at +260.

Mandatory Credit: Imagn Images

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I am a content writer for the NFL team, and joined The Playoffs after working with Sportskeeda and NFL Analysis as an NFL writer. After starting my professional career as a French-to-English translator, working as a content writer is a new adventure for me. I started out in the sports media field for two main reasons: my love for sports in general, especially the NFL, NBA, and Tennis, as well as my passion for writing. The best part of this job is that I get to write a variety of pieces with the freedom to explore content from various angles. It also enables me to stay up to date with the sporting world, which otherwise can be difficult to do in the day-to-day grind. In a world full of chaos, sports unite and entertain like nothing else!

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