Lions vs Giants Predictions, Odds and Best Bets For Week 12 of the 2025-26 NFL Season

The Lions will look to bounce back from their Week 11 loss to the Eagles

Lions vs Giants Predictions, Odds and Best Bets For Week 12 of the 2025-26 NFL Season

This game between the Detroit Lions and the New York Giants is another one of those games that have the makings to be a blowout. The Lions are in the hunt for a place in the playoffs with a 6-4 record and need to win this game to keep up the pressure. There is really no coming back for the Giants this year with a 2-9 record.

Game Details:

Time: 1:00 p.m. ET
Date: Sunday, November 23, 2025
Location: Ford Field, Detroit, Michigan
TV Channel: FOX
Streaming: Fubo, Hulu+ Live TV, NFL+

Recommended bets and updated odds

Recommended Bets	FanDuel	BetMGM
Jared Goff 250+ Passing Yards	-120	-139
Tyrone Tracy Jr. Under 12.5 Rush Attempts	-136	-118
Jahmyr Gibbs Anytime TD	-310	-265

Analysis and Rationale

It’s been another great season by Jared Goff through 11 weeks of football. He has thrown for 250 or more yards in five of his ten games, but more recently, he has pulled off 3 consecutive games with 250+ passing yards.

After the Giants were hit with Cam Scattebo’s season-ending injury, Tyrone Tracy Jr. has taken over as their primary running back. In his last two games, Tracy carried the ball 14 times against the Bears and 19 times against the Packers, but the Lions are a top-10 run defense team. Adding to the fact that Detroit should jump out to an early lead, the Giants may have to use the aerial route more.

Jahmry Gibbs has been electric in the backfield for the Lions. In ten games, he has 732 yards and 8 rushing touchdowns. Moreover, he also has 2 receiving touchdowns. Although the Lions run the ball with both Gibbs and David Montgomery, Gibbs has a tendency to get into the endzone.

The @Lions have yet to allow a 300-yard passer or 100-yard rusher this season.

The last time Detroit did not allow a 300-yard passer or 100-yard rusher through the first 10 games of any season was in 1969.#OnePride pic.twitter.com/3id0sXkGjd
— Detroit Lions PR (@LionsPR) November 19, 2025

Lions vs Giants Prediction

When the Lions are rolling, they are one of the toughest teams to stop. Against this Giants’ defense, Detroit should not have a hard time scoring at will. New York’s offense is already dealing with injuries to key players. Ideally, this game could be over well before the time runs out.

Prediction: Detroit Lions to win and cover the spread.

Week 12 Lions vs Giants Betting Odds and Spread

The moneyline and spread show the Detroit Lions are massive favorites in this matchup against the New York Giants. (Sourced from FanDuel).

	Moneyline	Spread	Total Points
Detroit Lions	-650	-10.5 (-102)	O 49.5 (-115)
New York Giants	+480	+10.5 (-120)	U 49.5 (-105)

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Lions vs Giants Best Bets

Here are the over/under and best player bets for the Detroit Lions and the New York Giants, as per FanDuel.

Detroit Lions Over/Under Odds

Below are some of the best over/under bets for the Detroit Lions.

Over/ Under Bets	Over	Under
Jared Goff Pass Completions	21.5 (-106)	21.5 (-125)
Amon-Ra St. Brown Total Receptions	7.5 (+128)	7.5 (-172)
David Montgomery Rush Attempts	11.5 (-122)	11.5 (-108)

Detroit Lions Best Player Bets

Below are some of the best player bets for the Detroit Lions.

Jared Goff 250+ Passing Yards: -120
Jameson Williams 60+ Receiving Yards: -120
Jahmry Gibbs Over 105.5 Total Scrimmage Yards: -118

If you’re looking for a complete guide to the best NFL betting sites, we’ve got you covered

The only team to put 30+ on either the Broncos or Eagles defense? The New York Giants… and they did it to both. 🔥 pic.twitter.com/SkryGkOrKW
— DraftKings (@DraftKings) November 19, 2025

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New York Giants Over/Under Odds

Below are some of the best over/under bets for the New York Giants.

Over/ Under Bets	Over	Under
Jaxson Dart Pass Attempts	30.5 (-122)	30.5 (-106)
Theo Johnson Total Receptions	4.5 (+142)	4.5 (-192)
Tyrone Tracy Jr. Rush Attempts	12.5 (+102)	12.5 (-136)

New York Giants Best Player Bets

Below are some of the best player bets for the New York Giants.

Jaxson Dart Under 1.5 Passing Touchdowns: -225
Wan’Dale Robinson Receiving 40+ Yards: -290
Tyrone Tracy Jr 40+ Rushing Yards: -182

The above odds are sourced from FanDuel. Use FanDuel to ace your betting game in all sports!

FAQs

What is the over/under for total points for the Lions vs Giants game?

The over/under for total points in the Lions vs Giants game is set at 49.5.

What is the point spread for the Lions vs Giants game?

The Lions come into the game as 10.5-point favorites over the Giants.

What is the moneyline for the Lions vs Giants game?

The Lions are the favorites with a moneyline of -650, while the Giants are the underdogs at +480.

Mandatory Credit: Imagn Images

Devavrat Kulkarni

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I am a content writer for the NFL team, and joined The Playoffs after working with Sportskeeda and NFL Analysis as an NFL writer. After starting my professional career as a French-to-English translator, working as a content writer is a new adventure for me. I started out in the sports media field for two main reasons: my love for sports in general, especially the NFL, NBA, and Tennis, as well as my passion for writing. The best part of this job is that I get to write a variety of pieces with the freedom to explore content from various angles. It also enables me to stay up to date with the sporting world, which otherwise can be difficult to do in the day-to-day grind. In a world full of chaos, sports unite and entertain like nothing else!