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Jaguars vs Colts Predictions, Odds and Best Bets For Week 14 of the 2025-26 NFL Season

Devavrat Kulkarni

Jaguars and Colts face off for the top spot in the AFC South!

American Football / NFL
07/12/2025 – 19:00
Jacksonville Jaguars
VS
19:00
07/12/2025
Indianapolis Colts
Odds updated on December 5, 2025 at 4:24 pm

Jaguars vs Colts Predictions, Odds and Best Bets For Week 14 of the 2025-26 NFL Season

This Jaguars vs Colts AFC South divisional matchup promises to be an exciting one as both teams are currently tied in the division with 8 wins and 4 losses. The winner of this game will get a massive boost. With the Texans lurking just behind, a win on Sunday will be even more crucial. 

Game Details:

  • Time: 1:00 p.m. ET
  • Date: Sunday, December 07, 2025
  • Location: EverBank Stadium, Jacksonville, Florida
  • TV Channel: CBS 
  • Streaming: Paramount+, Fubo, NFL+

Recommended bets and updated odds

Recommended BetsFanDuelBetMGM
Jonathan Taylor Under 92.5 Rushing Yards-114-113
Daniel Jones Over 1.5 Touchdown Passes+114+114
Jacksonville Jaguars to win+104+104
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Analysis and Rationale

Jonathan Taylor is one of the best running backs in the league this season, but he has not rushed for 90 yards in the past couple of games. Moreover, the Jaguars’ run defense has risen to the top of the league, allowing just 989 yards from 12 games for an average of 82.4 rushing yards per game. 

Daniel Jones has a total of 19 touchdown passes from 12 games, but more importantly, he has thrown for 2 or more touchdowns in 6 of those games. Ideally, the Colts may have to resort to the aerial route if the Jaguars are able to shut down their run game. 

Both the Jaguars and the Colts are heading in opposite directions of late. While Jacksonville is currently on a three-game win streak, Indianapolis has lost 2 in a row. It is rather strange to see the Colts falter and lose the lead in the division after starting the season 8 and 2, but what that has done is given the momentum to Jacksonville. 

Jaguars vs Colts Prediction

Initially, the way the season started for the Colts, it seemed that they would run away with the division. However, they have now lost three of their last four games, with the only win coming against the struggling Atlanta Falcons. 

On the flip side, the Jaguars have taken control of the AFC South with three wins on the trot. That being said, Jacksonville’s wins have come against underperforming teams, but the momentum and home-field advantage could be enough to sway this game in their favor.

Prediction: Jacksonville Jaguars to win.  

Week 14 Jaguars vs Colts Betting Odds and Spread

The moneyline and spread show the Indianapolis Colts are slight favorites in this matchup against the Jacksonville Jaguars. (Sourced from FanDuel)

MoneylineSpreadTotal Points
Jacksonville Jaguars+104+1.5 (-108)O 46.5 (-115)
Indianapolis Colts-124-1.5 (-112)U 46.5 (-105)
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Jaguars vs Colts Best Bets

Here are the over/under and best player bets for the Jacksonville Jaguars and the Indianapolis Colts, as per FanDuel.

Jacksonville Jaguars Over/Under Odds

Below are some of the best over/under bets for the Jacksonville Jaguars.

Over/ Under BetsOver Under
Trevor Lawrence Pass Attempts32.5 (-120)32.5 (-106)
Brian Thomas Jr. Total Receptions3.5 (-130)3.5 (-102)
Travis Etienne Rush Attempts13.5 (-122)13.5 (-108)

Jacksonville Jaguars Best Player Bets

Below are some of the best player bets for the Jacksonville Jaguars.

  • Trevor Lawrence 200+ Passing Yards: -200
  • Jakobi Meyers 50+ Passing Yards: -136
  • Travis Etienne 50+ Rushing Yards: -188

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Indianapolis Colts Over/Under Odds

Below are some of the best over/under bets for the Indianapolis Colts.

Over/ Under BetsOver Under
Daniel Jones Pass Attempts32.5 (-110)32.5 (-118)
Tyler Warren Total Receptions 4.5 (-148)4.5 (+112)
Jonathan Taylor Rush Attempts20.5 (-114)20.5 (-114)

Indianapolis Colts Best Player Bets

Below are some of the best player bets for the Indianapolis Colts.

  • Daniel Jones 250+ Passing Yards: +140
  • Michael Pittman Jr. 50+ Receiving Yards: -114
  • Jonathan Taylor 80+ Rushing Yards: -220

The above odds are sourced from FanDuel. Use FanDuel to ace your betting game in all sports!

FAQs

What is the over/under for total points for the Jaguars vs Colts game?

The over/under for total points in the Jaguars vs Colts game is set at 46.5.

What is the point spread for the Jaguars vs Colts game?

The Colts come into the game as 1.5-point favorites over the Jaguars.

What is the moneyline for the Jaguars vs Colts game?

The Colts are the favorites with a moneyline of -124, while the Jaguars are the underdogs at +104.

Mandatory Credit: Imagn Images

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I am a content writer for the NFL team, and joined The Playoffs after working with Sportskeeda and NFL Analysis as an NFL writer. After starting my professional career as a French-to-English translator, working as a content writer is a new adventure for me. I started out in the sports media field for two main reasons: my love for sports in general, especially the NFL, NBA, and Tennis, as well as my passion for writing. The best part of this job is that I get to write a variety of pieces with the freedom to explore content from various angles. It also enables me to stay up to date with the sporting world, which otherwise can be difficult to do in the day-to-day grind. In a world full of chaos, sports unite and entertain like nothing else!

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