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Inter Milan vs AC Milan Preview, Betting Odds and Predictions – 23/11/25

Moumita Dutta

The Derby della Madonnina returns to San Siro with Inter and AC Milan separated by a narrow margin in the title race. This first league meeting of the season carries heavy weight. Both clubs are determined to establish early momentum in a tightly contested Scudetto battle.

Nerazzurri are travelling into the fixture buoyed by prolific attacking displays and a run of impressive results under Cristian Chivu. Rossoneri are arriving with steady form and tactical stability under Massimiliano Allegri, making Sunday’s clash a classic test of firepower versus organisation.

Inter Milan vs AC Milan Best Bets

BetsStatusMoneyline
Total GoalsUnder 2.5-115
Total ShotsOver 27.5-138
Total Shots on TargetOver 9.5+110
Total CornersUnder 8.5+115
Total CardsUnder 4.5-125
Inter Milan Goalkeeper SavesOver 3.5+185
AC Milan Goalkeeper SavesOver 3.5+115

Inter Milan vs AC Milan Preview

Inter Milan

Inter lead the scoring charts this season and have been relentless in attack. They’re averaging over two goals per game across recent matches. Cristian Chivu’s side have won the majority of their last league outings. They will rely on a strike partnership that includes Lautaro Martínez and Marcus Thuram. 

Defensive absences could complicate selection. Denzel Dumfries is managing an ankle problem and faces a race to be fit. Meanwhile Henrikh Mkhitaryan and Matteo Darmian remain sidelined. Inter must balance rotation with the demands of upcoming European fixtures.

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AC Milan

AC Milan are arriving having rebuilt some consistency under Massimiliano Allegri. They’re unbeaten across league and cup in recent weeks. Their forward options are slimmer. Santiago Gimenez is out, but Rafael Leao and Christian Pulisic are expected to lead the line. 

They will be supported by creative midfield returns such as Adrien Rabiot. Selection choices persist at left-back, where Davide Bartesaghi is slightly favoured over Pervis Estupinan. Milan’s form suggests resilience. But they’ll need to contain Inter’s high-volume attacking play to claim a positive result.

Inter Milan vs AC Milan Over/ Under Predictions

Total Goals Under 2.5 @ -115 as per BetMGM:

Despite Inter’s scoring numbers, the derby often turns cagey as both coaches prioritise structure and discipline. Inter have been clinical in bursts. But the fixture’s intensity and tactical caution typically suppress open end-to-end exchanges. Especially with key defenders pushed and managers wary of costly mistakes. 

Recent derbies and cup battles have frequently produced low scoring tallies. Teams have locked up space in midfield and protected against counterattacks. Given Inter’s marginally better form and Milan’s compact approach, backing under 2.5 goals at -115 reflects the likelihood of a tight, controlled encounter rather than a goal glut. 

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Inter Milan vs AC Milan Player Picks

Lautaro Martinez to score anytime @ +150 as per FanDuel:

Lautaro remains Inter’s focal point and has a strong history of producing in big games. He has been among Inter’s most reliable scorers this campaign. He also repeatedly steps up in derby fixtures. His movement inside the box, aerial presence and timing on late runs make him a clear threat whenever Inter press forward. Martinez is closing in on double-figure tallies and enjoying decent momentum. So, an anytime goal selection at +150 offers upside when you expect Inter to edge the match via a decisive strike from their captain. 

Marcus Thuram to either score or assist anytime @ +115 as per FanDuel:

Marcus Thuram has been integral to Inter’s attacking variety. He has contributed goals and creative actions since arriving. His physicality and ability to link play create scoring chances both for himself and teammates. Thuram has registered multiple goal involvements this season and has produced significant expected-assist figures per 90. Should Inter dominate territory and create the higher volume of clear chances, Thuram is well placed to either finish one himself or set up Martinez or Bonny. The +115 price for goal/assist markets looks reasonably priced given his recent returns.

Inter Milan vs AC Milan Predictions

PicksMoneyline
Lautaro Martinez to score first+420
Marcus Thuram to score anytime+175
Hakan Calhanoglu to assist anytime+290
Francesco Pio Esposito to either score or assist+125
Adrien Rabiot to see a card+150

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Inter are heading into the derby with superior recent form and the league’s most potent attack. Yet the unique pressures of the Madonnina often yield measured games. It should be a narrow margin result, disciplined and decided by moments of finishing quality rather than a wide open shootout.

Final Prediction: Inter Milan 2-0 AC Milan

Expect Inter to control possession phases and probe Milan for weaknesses. They could convert one goal from a sustained spell of pressure and another from a set-piece or counter when space opens. Rossoneri, compact and cautious, will frustrate but struggle to produce high-quality chances against a tight Nerazzurri backline patched up for the occasion. With Lautaro likely to influence the scoreline and Thuram offering a second attacking option, a 2-0 Inter win seems like a realistic outcome.

When and where is the Inter Milan vs AC Milan game?

The Inter Milan vs AC Milan Serie A clash is on November 23, 2025, at San Siro Stadium, Milan, Italy.

What are the BetMGM betting odds for the Inter Milan vs AC Milan game?

Inter Milan are favorites to win with a moneyline at -102, to draw at +250 and for AC Milan to win at +280.

Name some key player prop bets for the game from BetMGM

Lautaro Martinez to score anytime: +180
Hakan Calhanoglu to assist anytime: +380
Marcus Thuram to either score or assist: +114

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Football writer at The Playoffs. I’ve been obsessed with the beautiful game since I was a kid.. Eventually, I realized I could combine my passion for writing with my love for football, and I’ve never looked back. My favorite part of the job is everything—when you’re doing what you love, even a late-night deadline feels like extra time in a thrilling cup final. Lastly, Lionel Messi is the GOAT.

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