Spurs vs Grizzlies Prediction, Odds & How to Watch – Tuesday, January 6

The San Antonio Spurs (25–10) travel to FedExForum to face the Memphis Grizzlies (15–20) on Tuesday night, with Memphis aiming to halt a four‑game losing streak. San Antonio enters as 5‑point favorites, led by Victor Wembanyama’s dominance in the paint and De’Aaron Fox’s scoring. Memphis, paced by Jaren Jackson Jr., has struggled with injuries and inconsistency, but remains competitive at home.

The over/under is set at 237.5, reflecting both teams’ offensive pace, though recent trends lean slightly toward the under. San Antonio has won 68.2% of games as favorites this season, while Memphis has covered in just 4 of 14 games as underdogs of 5+.

With NBA predictions and betting picks focused on efficiency, rebounding, and star matchups, we’ll also highlight a same‑game parlay and favorite player props in tonight’s NBA odds. Here’s how we’re betting Spurs vs Grizzlies tonight.

Best Bet for Spurs vs Grizzlies

Best Bet: Grizzlies +5 (-110) Book: Best price at DraftKings

Our best bet for Spurs vs Grizzlies is Grizzlies +5 (-110) against the spread.

Memphis averages 116.0 points per game, nearly matching San Antonio’s defensive allowance (114.2). Jaren Jackson Jr. and Santi Aldama provide interior scoring and rebounding, while Cam Spencer adds perimeter shooting.

The Spurs are strong overall but only 5–6–2 ATS when favored by 5+, showing vulnerability in covering mid‑range spreads. Memphis has an 11–8 ATS record when scoring more than 114 points, and their home crowd often boosts performance. Given the spread and current form, we’re backing Memphis to cover +5 (-110) in a competitive game.

Same‑Game Parlay Picks for Spurs vs Grizzlies

3‑Leg SGP (Safer)

Leg 1: Grizzlies +7.5 alt spread
Leg 2: Jaren Jackson Jr. 15+ points
Leg 3: Victor Wembanyama 10+ rebounds
Combined odds: +400

Longshot SGP (+1200)

Leg 1: Spurs -7.5 alt spread
Leg 2: Wembanyama 25+ points
Leg 3: Spencer 3+ threes

Spurs vs Grizzlies Odds & Top Player Props

Here are the latest Spurs vs Grizzlies odds from top sportsbooks. Shop around for the best NBA odds before you lock in your bets.

Market	San Antonio Spurs	Memphis Grizzlies
Money Line	-225	+186
Spread	-5.5 (-110)	+5.5 (-110)
Total	O 238.5 (-110)	U 238.5 (-110)

Odds updated: January 6, 2026 – 12:00 p.m. ET. Lines may move throughout the day. You can find more live numbers on our NBA odds today page.

Top Player Prop Odds

Victor Wembanyama points O/U 24.5 (-112)
Jaren Jackson Jr. points O/U 18.5 (-110)
De’Aaron Fox assists O/U 6.5 (-108)

For more markets, check out our dedicated Best NBA player props today page.

Trends to Know for Spurs vs Grizzlies

Spurs are 5–6–2 ATS when favored by 5+.
Grizzlies are 4–9–1 ATS as underdogs of 5+.
Over has hit in 45.7% of Spurs games, 40% of Grizzlies games.
Spurs are 19–2 when scoring 117+.
Grizzlies are 11–8 when scoring 115+.

Latest Injuries & NBA Injury Report for Spurs vs Grizzlies

Before betting this game, it’s important to check the NBA injury report, as late scratches and minutes limits can swing spreads and totals in a hurry.

Team	Player	Injury	Status
San Antonio Spurs	Devin Vassell	Thigh	Out
San Antonio Spurs	Victor Wembanyama	Knee	Day-to-Day
Memphis Grizzlies	Ja Morant	Calf	Day-to-Day
Memphis Grizzlies	Vince Williams	Knee	Day-to-Day
Memphis Grizzlies	Cedric Coward	Ankle	Day-to-Day
Memphis Grizzlies	Ty Jerome	Calf	Out
Memphis Grizzlies	John Konchar	Thumb	Out
Memphis Grizzlies	Brandon Clarke	Calf	Out
Memphis Grizzlies	Zach Edey	Ankle	Out
Memphis Grizzlies	Scotty Pippen Jr.	Toe	Out

In the NBA, late injury news and minutes restrictions have a huge impact on spreads and totals, so re‑check the injury report and final inactives about an hour before tip‑off.