The NFL Playoffs is here and one of the more intriguing matchups is a Wild Card round contest between the Eagles vs 49ers, a clash between the NFC East division winner vs a dark horse contender from NFC West. Both teams have elite talents, but it will all come down to who can make timely stops, coaching adjustments, and the star players to show up for the massive contracts they’ve signed.
The Eagles had an okay regular season at best, as all year long they’ve battled with offensive irregularities and their once elite defense has now come down. Saquon Barkley mightily struggled this season and was nowhere close to where he was last season. Similarly, Jalen Hurts has had a down season to say the least and neither his arm nor his running game was exactly reliable. A lot needs to be fixed. However, they have little to no time remaining to prepare for what’s to come.
Meanwhile, the 49ers have proven many people wrong this season and despite multiple injuries during the season, they are in the playoffs and with their offense clicking during the final stretch of games. Even though they are 3rd in this division, they still have a 12-5 record and have pulled off wins against some of the best teams, making them a dark horse team in the playoffs.
What that said, let us take a look at anytime TD scorers for this Eagles vs 49ers Wild Card round game.
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Christian McCaffrey Anytime TD vs Philadelphia Eagles (-140)
Christian McCaffrey’s Anytime TD at -140 is a strong bet against the Eagles. In 2025, he tallied 17 total touchdowns (rushing and receiving), scoring in all but four games while leading San Francisco’s red-zone attack. Philadelphia allowed 18 rushing scores this season , ranking mid-pack against the run. McCaffrey has 3 TDs in 4 career games (regular season+ playoffs) vs Philly, including one in the 2023 NFC Championships. As the 49ers’ workhorse in a high-scoring offense, he exploits goal-line opportunities effectively.
Saquon Barkley Anytime TD vs San Francisco 49ers (-125)
Saquon Barkley anytime TD at -125 is a strong bet against the 49ers as San Francisco has a strong rush defense but are 15th in red-zone defense and 13th in scoring defense, leaving holes for Philadelphia to exploit. He recorded 3 TDs in the last four games of the regular season, and had multiple 100+ yards performance in the same stretch, making this a safe bet.
Jalen Hurts Anytime TD vs San Francisco 49ers (+120)
Jalen Hurts’ anytime TD at +120 is strong bet vs. the 49ers. In 2025, he rushed for 8 touchdowns in 16 games, excelling in goal-line situations with the tush push. San Francisco allowed just 12 rushing TDs all season (0.67 per game), but Hurts scored a rushing TD in their 2023 matchup and thrives in playoffs (multiple in past NFC Championship vs. SF). Eagles’ red-zone dominance and Hurts’ sneaks make +120 excellent value.
A.J. Brown Anytime TD vs San Francisco 49ers (+125)
A.J. Brown’s Anytime TD at +125 is a strong bet vs. the 49ers. In 2025, he recorded 7 receiving touchdowns in 15 games, serving as Philadelphia’s primary red-zone threat alongside DeVonta Smith. San Francisco’s defense allowed receiving TDs to WRs throughout the season, ranking mid-pack in pass defense despite injuries. Brown has 1 TD in 2 career games vs. SF (259 yards total). With Jalen Hurts targeting him heavily in scoring position, +125 offers solid value in a potential shootout.
Anytime TD Betting Card for Eagles vs 49ers
Here is a quick recap for the Eagles vs 49ers anytime touchdown scorers and their odds as sourced via BetMGM.
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I cover the National Football League and things cannot get better than that. I always dreamed to play football or basketball professionally since I’m built like a Running Back. But now that I can’t, since I’m technically in the “Unc” age, I thought why not pick a career in sports industry? So here I am, doing what I love, and hoping that the Commanders win the Super Bowl. I give love to players when it’s due, but can be critical about their performances at the same time. Enough about me, now let my articles do all the talking.
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