Detroit Pistons vs New Orleans Pelicans Prediction, Picks and Odds for Thursday, March 26

The Detroit Pistons are set to welcome the New Orleans Pelicans in a cross-conference clash on Thursday, March 26. The Pistons sit atop the Eastern Conference with a strong 51-19 record, while the New Orleans Pelicans are near the bottom of the Western Conference at 25-47. The Pistons have been one of the league’s most consistent teams and hold a solid home record. The Pelicans have struggled heavily on the road with a poor 9-25 record.

The Pistons are around -5.5 favorites with moneyline at -205 and a total near 224.5. These NBA odds tonight suggest that the Pistons are highly likely to record a win at home, and reflect the clear gap between the Eastern Conference leaders and a struggling team.

Here’s how we’re betting Pistons vs Pelicans tonight.

Best Bet for Detroit Pistons vs New Orleans Pelicans

Best Bet: Pistons -5.5 (-106)

Book: Best price on FanDuel

Our best bet for Detroit Pistons vs New Orleans Pelicans is Pistons -5.5 (-106) against the spread.

Detroit ranks among the NBA’s elite in both offensive and defensive efficiency as well as a strong net rating. They dominate games well at home, and protect the spread against lesser opponents. On the other hand, New Orleans sits with one of the weaker offenses and defenses in the league.

The spread at Pistons -5.5 fits the hosts well considering their control of the game at home as well as better overall depth in this spot. Given the matchup, Detroit’s efficiency edge, and the current spread, we’re taking the Pistons to cover this number comfortably.

Same-Game Parlay Picks for Pistons vs Pelicans

3-Leg SGP (Safer)

Leg 1: Jalen Duren Over 23.5 points
Leg 2: Daniss Jenkins Over 17.5 points
Leg 3: Tobias Harris Over 14.5 points

Combined odds: +695

We have built this same-game parlay around the Pistons to record a comfortable win at home. With Cade Cunningham currently out of action, players such as Jalen Duren, Jenkins and Harris are expected to take charge of their scoring.

These legs are correlated considering if they control the tempo of the game, they would be able to generate efficient scoring opportunities. Hence, this is our safer SGP option.

Detroit Pistons vs New Orleans Pelicans Odds & Top Player Props

Here are the latest Pistons vs Pelicans odds from top sportsbooks. Shop around for the best NBA odds before locking in your bets.

Team	Spread	Moneyline	Total
New Orleans Pelicans	+5.5 (-110)	+180	O 225.5 (-110)
Detroit Pistons	-5.5 (-110)	-220	U 225.5 (-110)

Odds from FanDuel, updated on Thursday, March 26, 2026 at 1:23 am EDT. Lines may change throughout the day.

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Top Player Prop Odds for Detroit Pistons vs New Orleans Pelicans

Given how prop-heavy NBA betting is, we’re also eyeing these player props for tonight’s Detroit Pistons vs New Orleans Pelicans game.

Trey Murphy III Over 20.5 points (+102)
Zion Williamson Over 20.5 points (-118)
Jalen Duren Over 12.5 rebounds (+108)

These props align with usage rates and matchup dynamics. Trey Murphy III and Zion Williamson are key Pelicans’ scorers and they would want to take their team’s offense in their hands and put up an efficient score against the stronger Pistons to keep themselves in the game. Apart from them, Duren is an efficient rebounder, who is expected to dominate the glass on Thursday as well.

Trends to Know for Detroit Pistons vs New Orleans Pelicans

Here are a few betting trends to keep in mind for Detroit Pistons vs New Orleans Pelicans.

The New Orleans Pelicans have been 9-1-0 ATS in their last ten games.
The Detroit Pistons have been 17-19-0 ATS at home this NBA season.
The Pistons have hit over in 32 of their 72 games thus far in the current NBA season.

Latest Injuries & NBA Injury Report for Detroit Pistons vs New Orleans Pelicans

Before betting this game, it’s important to check the NBA injury report as late scratches and minutes limits can swing spreads and totals in a hurry.

Team	Player	Injury	Status
Detroit Pistons	Isaiah Stewart	Calf	Out
Detroit Pistons	Marcus Sasser	Hip	Out
Detroit Pistons	Cade Cunningham	Chest	Out
New Orleans Pelicans	Dejounte Murray	Rest	Questionable
New Orleans Pelicans	Trey Murphy III	Ankle	Questionable
New Orleans Pelicans	Bryce McGowens	Toe	Out

In the NBA, late injury news and minutes restrictions have a huge impact on spreads and totals, so re-check the injury report and final inactives about an hour before tip-off.

What time is Detroit Pistons vs New Orleans Pelicans on Thursday?

The Detroit Pistons vs New Orleans Pelicans is scheduled to tip off at 7:00 pm EDT on March 26.

Where will Detroit Pistons vs New Orleans Pelicans be played?

The Detroit Pistons vs New Orleans Pelicans will be played at Little Caesars Arena, Detroit, MI.

Where can I watch Detroit Pistons vs New Orleans Pelicans on TV and live stream?

The Detroit Pistons vs New Orleans Pelicans will be available on FanDuel Sports Network. The live stream, on the other hand, will be accessible on Fubo and NBA League Pass.

Detail	Information
Date	Thursday, March 26, 2026
Time	7:00 pm EDT
Venue	Little Caesars Arena, Detroit, MI
TV / Live Stream	FanDuel Sports Network, NBA League Pass, Fubo