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Denver Nuggets vs Portland Trail Blazers Prediction, Picks and Odds for Sunday, March 22 

Garima Ranawat
Basketball / NBA
22/03/2026 – 22:00
Denver Nuggets
VS
22:00
22/03/2026
Portland Trail Blazers
Odds updated on March 22, 2026 at 4:07 am

The Denver Nuggets will welcome the Portland Trail Blazers on Sunday at Ball Arena in Denver on Sunday, March 22. The Nuggets are entering the game on the back of a 43-28 win-loss record, and a recent win over the Toronto Raptors. The Trail Blazers, on the other hand, are seeded ninth in the Western Conference standings, and they are coming off a three-game winning streak. 

The Nuggets are 9-point favorites with moneyline at -335 and a total around 242.5 points. These NBA odds today suggest that the Nuggets are highly-likely to emerge victorious over their counterparts. We have our best bet, a same-game parlay, and a few player props for tonight’s game. 

Here’s how we are betting for the Denver Nuggets vs Portland Trail Blazers tonight. 

Best Bet for Denver Nuggets vs Portland Trail Blazers 

Our best bet for Denver Nuggets vs Portland Trail Blazers is the Nuggets -9 (-106) against the spread. 

The Denver Nuggets maintain a 20-13 win-loss record at home, while they have recorded six wins in their last ten games. The Nuggets have the best offensive rating in the league, while their defense puts them in the 21st spot. The Trail Blazers, on the other hand, are seeded on the 24th spot in both metrics. 

The spread at Nuggets -9 (-106) fits the hosts well considering their elite offense and better defense. They cover well in such spots. 

Thus, keeping their overall edge in mind, we are laying the Nuggets -9 (-106) as our best bet, and expect the hosts to cover the number today. 

Same-Game Parlay Picks for Denver Nuggets vs Portland Trail Blazers 

3-Leg SGP (Safer) 

  • Leg 1: Denver Nuggets -10.5 (alternate spread)
  • Leg 2: Nikola Jokic Over 27.5 points 
  • Leg 3: Jamal Murray Over 23.5 points 

Combined odds: +590 

We have built this same-game parlay around the Nuggets to record a win over the Trail Blazers. Nikola Jokic is the leading scorer for the Nuggets, and we can expect him to leverage his team’s better offense to put up a good score. Murray can also be relied upon to come up with significant gameplay. 

These legs are correlated considering if the Nuggets take control of the game, their players will get ample scoring opportunities. This way, the Nuggets will end up with more volume. Hence, this is our safer SGP option. 

Denver Nuggets vs Portland Trail Blazers Odds and Top Player Props 

Here are the latest Denver Nuggets vs Portland Trail Blazers odds from top sportsbooks. Shop around for the best NBA odds before locking in your bets. 

Team Spread Moneyline Total 
Portland Trail Blazers +9 (-114)+270O 242.5 (-108)
Denver Nuggets -9 (-106)-335U 242.5 (-112)

Odds from FanDuel, updated on Sunday, March 22, 2026 at 5:27 am EDT. Lines may move throughout the day. 

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Denver Nuggets vs Portland Trail Blazers Top Player Props Odds 

Given how prop-heavy NBA betting is, we are also eyeing these player props for Denver Nuggets vs Portland Trail Blazers. 

  • Deni Avdija Over 23.5 points (-114)
  • Jerami Grant Over 17.5 points (-122)
  • Nikola Jokic Over 12.5 rebounds (-102)

These legs fit well into usage and volume. Deni Avdija and Jerami Grant will be expected to come up with crucial offensive performances to keep their team in the game. Apart from them, Jokic is a solid rebounder, and he would want to make the most of the Nuggets’ overall edge to record a significant number on the glass. 

Trends to Know for Denver Nuggets vs Portland Trail Blazers

Here are a few betting trends to keep in mind for Denver Nuggets vs Portland Trail Blazers. 

  • The Trail Blazers have been 4-6-0 ATS in their last ten games. 
  • The Nuggets have been 16-17-0 ATS at home this NBA season. 
  • Over has hit the Nuggets in 43 of their 71 games thus far in the current NBA season. 

Latest Injuries and NBA Injury Report for Denver Nuggets vs Portland Trail Blazers

Before betting this game, it’s important to check the NBA injury report, as late scratches and minutes limits can swing spreads and totals in a hurry.

Team Player Injury Status 
Denver Nuggets Peyton Watson Hamstring Questionable 
Portland Trail Blazers Vit Krejci Calf Questionable 
Portland Trail Blazers Shaedon Sharpe Calf Out 
Portland Trail Blazers Damian Lillard Achilles Out 
Portland Trail Blazers Jerami Grant Foot Questionable 

In the NBA, late injury news and minutes restrictions have a huge impact on spreads and totals, so re-check the injury report and final inactives about an hour before tip-off.

What time is Denver Nuggets vs Portland Trail Blazers on Sunday? 

The Denver Nuggets vs Portland Trail Blazers is scheduled to tip off at 5:00 pm EDT on March 22. 

Where will Denver Nuggets vs Portland Trail Blazers be played? 

The Denver Nuggets vs Portland Trail Blazers will be played at Ball Arena in Denver, CO. 

Where can I watch Denver Nuggets vs Portland Trail Blazers on TV and live stream? 

The Denver Nuggets vs Portland Trail Blazers will be available on NBA TV. The live stream, on the other hand, will be accessible on Fubo and NBA League Pass. 

DetailInformation
Date Sunday, March 22, 2026
Time 5:00 pm EDT
Venue Ball Arena in Denver, CO
TV / Live Stream NBA TV, NBA League Pass, Fubo
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