Charlotte Hornets vs Memphis Grizzlies Prediction, Picks and Odds for Saturday, March 21

The Charlotte Hornets will be up against the Memphis Grizzlies on Saturday, at home, Spectrum Center in Charlotte. The Grizzlies are seeded 12th in the West, and they will enter the matchup on the back of a loss. In their last ten games, the Grizzlies have been able to win only one game. The Hornets, on the other hand, are seeded tenth in the East, and they are coming off two back-to-back victories

The Hornets are 16.5-point favorites with moneyline at -1400 and a total around 235.5 points. These NBA odds tonight suggest that the Hornets are highly-likely to record the victory, and make the most of their homecourt advantage. We have got our Best Bet, a same-game parlay, and a few player props for tonight’s game.

Here’s how we are betting for the Charlotte Hornets vs Memphis Grizzlies on Saturday.

Best Bet for Charlotte Hornets vs Memphis Grizzlies

Best Bet: Charlotte Hornets -16.5 (-110)

Book: Best Price at FanDuel

Our best bet for Charlotte Hornets vs Memphis Grizzlies is Hornets -16.5 (-110) against the spread.

The Charlotte Hornets have recorded 16 wins in their 33 games thus far at home, and have emerged victorious in 7 of their last ten fixtures. In addition to it, they are coming off two back-to-back wins. The Grizzlies, on the other hand, are struggling with just 11 wins in 34 games on the road thus far, and have lost nine of their last ten games.

In addition to it, the Hornets have the sixth-best offensive rating, while their defense puts them in the 15th spot. On the flip side, the Grizzlies are amongst the bottom ten teams in both offense as well as defense.

The spread at Hornets -16.5 fits the hosts well considering their elite on-court balance as well as homecourt advantage. They generally cover well in such spots.

Keeping their overall edge in mind, we are comfortably laying the Charlotte Hornets -16.5 (-110) as our Best Bet, and expect the hosts to cover the number easily tonight.

Same-Game Parlay Picks for Charlotte Hornets vs Memphis Grizzlies

3-Leg SGP (Safer)

Leg 1: Charlotte Hornets -20.5 (alternate spread)
Leg 2: LaMelo Ball Over 19.5 points
Leg 3: Brandon Miller Over 20.5 points

Combined odds: +665

We have built this same-game parlay around the Charlotte Hornets to record a dominating win over the Grizzlies. Brandon Miller and LaMelo Ball have taken offensive charge for the side in the current NBA season. They would aim to leverage on the stronger on-court perimeter of their team, and put up strong offensive performance against the weaker Grizzlies.

These legs are correlated, considering if the Hornets take control of the game right from the beginning, their players will get ample scoring opportunities. Thus, they will end up with more volume. Hence, this is our safer SGP option.

Charlotte Hornets vs Memphis Grizzlies Odds and Top Player Props

Here are the latest Charlotte Hornets vs Memphis Grizzlies odds from top sportsbooks. Shop around for the best NBA odds before locking in your bets.

Team	Spread	Moneyline	Total
Memphis Grizzlies	+16.5 (-110)	+830	O 235.5 (-110)
Charlotte Hornets	-16.5 (-110)	-1400	U 235.5 (-110)

Odds from FanDuel, updated on Saturday, March 21, 2026 at 6:08 am EDT. Lines may move throughout the day.

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Charlotte Hornets vs Memphis Grizzlies Top Player Prop Odds

Given how prop-heavy NBA betting is, we are also eyeing these player props for Charlotte Hornets vs Memphis Grizzlies on Saturday.

GG Jackson II Over 14.5 points (-125)
Jaylen Wells Over 12.5 points (+102)
Moussa Diabate Over 9.5 rebounds (-114)

These legs fit well into usage and volume. GG Jackson II and Jaylen Wells would be expected to take on scoring responsibility for their side to put up some score against the Hornets. Apart from them, Diabate has a solid dominance on the glass, and we see him doing the same against the Grizzlies.

Trends to Know for Charlotte Hornets vs Memphis Grizzlies

Here are a few betting trends to keep in mind for Charlotte Hornets vs Memphis Grizzlies.

The Hornets have been 21-12-0 ATS at home this NBA season.
The Memphis Grizzlies have gone 17-16-1 ATS on the road thus far.
In their last ten games, the Hornets have been 5-5-0 ATS.

Latest Injuries and NBA Injury Report for Charlotte Hornets vs Memphis Grizzlies

Before betting this game, it’s important to check the NBA injury report, as late scratches and minutes limits can swing spreads and totals in a hurry.

Team	Player	Injury	Status
Charlotte Hornets	Tidjane Salaun	Calf	Out
Memphis Grizzlies	Taj Gibson	Foot	Questionable
Memphis Grizzlies	Brandon Clarke	Calf	Out
Memphis Grizzlies	Ja Morant	Elbow	Questionable
Memphis Grizzlies	Jahmai Mashack	Ankle	Questionable
Memphis Grizzlies	Gregory Jackson	Knee	Questionable
Memphis Grizzlies	Cedric Coward	Personal	Questionable
Memphis Grizzlies	Santi Aldama	Knee	Out
Memphis Grizzlies	Scotty Pippen Jr	Toe	Out
Memphis Grizzlies	Zach Edey	Ankle	Out
Memphis Grizzlies	Kentavious Caldwell-Pope	Finger	Out

In the NBA, late injury news and minutes restrictions have a huge impact on spreads and totals, so re-check the injury report and final inactives about an hour before tip-off.

What time is Charlotte Hornets vs Memphis Grizzlies on Saturday?

The Charlotte Hornets vs Memphis Grizzlies is scheduled to tip off at 7:00 pm EDT on March 21.

Where will Charlotte Hornets vs Memphis Grizzlies be played?

The Charlotte Hornets vs Memphis Grizzlies will be played at Spectrum Center, Charlotte, NC.

Where can I watch Charlotte Hornets vs Memphis Grizzlies on TV and live stream?

The Charlotte Hornets vs Memphis Grizzlies will be available on FanDuel SN SE. The live stream, on the other hand, will be accessible on Fubo and NBA League Pass.