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Boston Celtics vs Indiana Pacers Predictions, Betting Odds and Best Bets for Monday, December 22

The Boston Celtics will welcome the Indiana Pacers for an NBA 2025-26 regular-season clash on December 22, 2025. This will be the first time these Eastern Conference teams will lock horns in the NBA 2025-26 season. The Celtics will head into the game on the back of a two-game winning streak, with their most-recent victory coming against the Toronto Raptors. On the other hand, the Indiana Pacers are coming off a four-game losing streak, with their recent setback against the New Orleans Pelicans.

Game Details

Date: Monday, December 22, 2025
Time: 7:30 pm ET
Venue: TD Garden in Boston, Massachusetts
TV: FDSIN and NBCS-BOS
Live Stream: NBA League Pass

Recommended Bet and Odds

Recommended Bet	FanDuel	BetMGM
Jaylen Brown O 29.5 Points	-130	–

Analysis and Rationale

Jaylen Brown has been leading the Celtics’ offensive charge, dropping an average of 29.3 points per game. He is shooting 50.0% from the field and 36.5% from the three-point range. Apart from it, Brown is dropping an average of 6.3 rebounds and 5.0 assists per game.

In the last game that Brown played, he poured in 30 points for the Celtics on 50.0% shooting from the field and 50.0% shooting from the three-point range. In fact, in his last five appearances, he has scored 30 points or more on all occasions, including a 34+ point show against the Detroit Pistons.

The Indiana Pacers, who had improved significantly recently with their all-around performances, have once again seen a dip. Currently, they are seeded 19th in the league with a defensive rating of 116.1, while the Celtics possess a mid-rack defensive rating in the season. Though Brown is listed as questionable, if he is cleared to play, we can expect him to drop 30 points or more against the Pacers on Monday.

Boston Celtics vs Indiana Pacers Predictions

The Boston Celtics, after getting off to a disappointing start of the season, have shown significant improvement off-late. They have been playing great basketball and have won seven of their last 10 games. At home, they have dominated their rivals in nine of 14 games, while having won 8 of their 14 games on road.

The Celtics are averaging 116.5 points per game, while allowing second least points at 110.5. It shows that while their defense is top notch, the 18-time champions could put effort into improving their offense. Boston is seeded third in terms of offensive rating at 121.3, while its defensive rating of 114.7 has given it 16-spot in the standings.

Jaylen Brown is leading offense for the Celtics, while Derrick White is leading them in steals and blocks. Apart from it, their injury report looks good for Monday’s game, though Brown and Jordan Walsh have been listed as questionable.

On the other hand, the Indiana Pacers, who had started showing improvement, are once again going through a slump. They are seeded 14th in the Eastern Conference standings with a 6-22 win-loss record. The Pacers will head into the upcoming game on the back of a four-game losing streak, with their most-recent defeat coming against the New Orleans Pelicans.

The Indiana Pacers are scoring 110.2 ppg, second worst in the league, while allowing 118.5 ppg. They have the worst offensive rating in the league at 108.1, while with a defensive rating of 116.1, they are seeded 19th in the league.

Given how the Pacers are struggling on both ends of the court, while the Celtics have been playing good basketball, we expect the hosts to take a lead on Monday.

Predictions: Boston Celtics to win.

Boston Celtics vs Indiana Pacers Betting Odds and Spread

According to moneyline odds and betting spread on FanDuel, the Boston Celtics are expected to record a heavy victory over the Indiana Pacers.

	Spread	Moneyline Odds	Total
Indiana Pacers	+10.5 (-114)	+380	O 224.5 (-110)
Boston Celtics	-10.5 (-106)	-490	U 224.5 (-110)

Boston Celtics vs Indiana Pacers Over/Under Odds and Best Bets

Boston Celtics Over/Under Odds

Recommended Bets	Over	Under
Payton Pritchard 18.5 points	-114	-114
Derrick White 18.5 points	-108	-122
Neemias Queta 9.5 rebounds	-106	-125

Boston Celtics Best Bets

Anfernee Simons to score 15+ points: +116
Jaylen Brown to record 8+ rebounds: +136
Neemias Queta to record a double-double: +190

Indiana Pacers Over/Under Odds

Recommended Bets	Over	Under
Pascal Siakam 22.5 points	-130	-102
Bennedict Mathurin 17.5 points	-118	-112
Pascal Siakam 6.5 rebounds	+112	-148

Indiana Pacers Best Bets

Andrew Nembhard to score 15+ points: -162
Isaiah Jackson to record 8+ rebounds: +190
Jay Huff to hit 3+ threes: +220

The odds given above have been sourced from FanDuel. Use FanDuel to ace your betting game across all sports.

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FAQs

What is the over/under for total points for the Celtics vs Pacers game?

The over/under for total points in the game between the Celtics and the Pacers is set at 2245.

What is the point spread for the Celtics vs Pacers game?

The Celtics have a solid 10.5-point edge over the Pacers.

What is the moneyline for the Celtics vs Pacers game on Monday?

The Celtics are favorites to win with moneyline odds of -490, while the Pacers are underdogs at +380.

Garima Ranawat

Garima is a sports writer with around two years of experience in Indian sports and a newfound interest in the NBA. Inspired by the leadership of cricketing legend MS Dhoni, she wishes to bring in newer perspectives to the NBA fanatics with her writing.