New Orleans Pelicans vs Philadelphia 76ers Prediction, Picks and Odds for Saturday, February 21

The New Orleans Pelicans will be up against the Philadelphia 76ers on Saturday at Smoothie King Center. Their last meeting saw the 76ers recording a big 10-point win, and in the forthcoming game, we could see the Pelicans avenging their past defeat. The 76ers are seeded sixth in the standings, and they will enter the matchup on the back of a three-game losing skid. The Pelicans, on the other hand, are one of the bottom-seeded teams in the West. They are entering the fixture off a 15-42 win-loss record, and are coming off a two-game losing skid.

The 76ers are 3.5-point favorites with moneyline at -164 and total around 230.5 points. These NBA odds tonight suggest that Philadelphia is likely to thrash the Pelicans in their own backyard. We have got our Best Bet, a same-game parlay, and a few player props for tonight’s game.

Here’s how we are betting New Orleans Pelicans vs Philadelphia 76ers tonight.

Best Bet for Philadelphia 76ers vs New Orleans Pelicans

Best Bet: Philadelphia 76ers -3.5 (-110)

Book: Best price at FanDuel

Our best bet for Philadelphia 76ers vs New Orleans Pelicans is 76ers -3.5 (-110) against the spread.

The Philadelphia 76ers maintain a favorable 15-10 record on the road thus far. The Pelicans, on the other hand, are struggling poorly even at home. Talking about their stats, the 76ers have the 13th-best offense in the league, while their defense seeds them the 15th spot. On the other hand, the Pelicans are seeded towards the bottom across statistical categories.

The spread at Philadelphia 76ers -3.5 (-110) fits the hosts well considering their better offense and defense. On the other hand, New Orleans is struggling, which further boosts Philadelphia’s chances to cover well.

Keeping their offensive and defensive edge in mind, we are laying Philadelphia 76ers -3.5 (-110) as our best bet, and expect them to cover the number comfortably.

Same-Game Parlay Picks for New Orleans Pelicans vs Philadelphia 76ers

3-Leg SGP (Safer)

Leg 1: Philadelphia 76ers -5.5 (alternate spread)
Leg 2: Tyrese Maxey Over 31.5 points
Leg 3: Kelly Oubre Jr. Over 16.5 points

Combined odds: +428

We have built this same-game parlay around the Philadelphia 76ers to win at New Orleans. With key absences for the 76ers, players such as Kelly Oubre Jr. are stepping up to take offensive charge alongside Tyrese Maxey. We expect them to take advantage of their better offense and defense to take control of the ball.

These legs are correlated considering if the Philadelphia 76ers dominate the court right from the beginning, their players will get volume. This way they will not only end up with more scoring opportunities and create more plays for their teammates. Thus, this is our safer SGP option.

New Orleans Pelicans vs Philadelphia 76ers Odds and Top Player Props

Here are the latest New Orleans Pelicans vs Philadelphia 76ers odds from top sportsbooks. Shop around for the latest NBA odds before locking in your bets.

Team	Spread	Moneyline	Total
Philadelphia 76ers	-3.5 (-110)	-164	O 230.5 (-108)
New Orleans Pelicans	+3.5 (-110)	+138	U 230.5 (-112)

Odds from FanDuel, updated on Saturday, February 21, 2026 at 2:15 am ET. Lines may move throughout the day.

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New Orleans Pelicans vs Philadelphia 76ers Top Player Prop Odds

Given how prop-heavy NBA betting is, we are also eyeing these player props for the New Orleans Pelicans vs Philadelphia 76ers tonight.

Zion Williamson over 23.5 points (-106)
Trey Murphy III over 21.5 points (-104)
Andre Drummond Over 10.5 rebounds (+116)

These legs fit well into usage and volume. Zion Williamson and Trey Murphy III lead the offensive charge for the Pelicans. We can expect them to push themselves against a stronger Philadelphia to keep their team in the game. Drummond has got a good grip on the board, and he is likely to grab a good number of rebounds for the 76ers.

Trends to Know for New Orleans Pelicans vs Philadelphia 76ers

Here are a few betting trends to know for New Orleans Pelicans vs Philadelphia 76ers.

The Philadelphia 76ers are 17-7-1 ATS on the road this season.
The Pelicans have been 5-5-0 ATS in their last ten games.
Over has hit the 76ers in 27 of their 55 games thus far

Latest Injuries and NBA Injury Report for New Orleans Pelicans vs Philadelphia 76ers

Before betting this game, it’s important to check the NBA injury report, as late scratches and minutes limits can swing spreads and totals in a hurry.

Team	Player	Injury	Status
New Orleans Pelicans	Jalen Suggs	Back	Questionable
New Orleans Pelicans	Franz Wagner	Ankle	Out
Philadelphia 76ers	Joel Embiid	Lower Leg	Out
Philadelphia 76ers	Paul George	Suspension	Out

In the NBA, late injury news and minutes restrictions have a huge impact on spreads and totals, so re-check the injury report and final inactives about an hour before tip-off.

What time is New Orleans Pelicans vs Philadelphia 76ers on Friday?

The New Orleans Pelicans vs Philadelphia 76ers is scheduled to tip off at 7:00 pm ET on Friday.

Where will New Orleans Pelicans vs Philadelphia 76ers be played?

The New Orleans Pelicans vs Philadelphia 76ers will be played at Smoothie King Center in New Orleans, LA.

Where can I watch New Orleans Pelicans vs Philadelphia 76ers on TV and live stream?

The New Orleans Pelicans vs Philadelphia 76ers will be available on Gulf Coast Sports. The live stream, on the other hand, will be accessible on Fubo and NBA League Pass.

Detail	Information
Date	Saturday, February 21, 2026
Time	7:00 pm ET
Venue	Smoothie King Center in New Orleans, LA
TV / Live Stream	Gulf Coast Sports, NBA League Pass, Fubo