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Boston Celtics vs Detroit Pistons Predictions, Betting Odds and Best Bets for Wednesday, November 26 

Garima Ranawat

The Boston Celtics are ready to host the Detroit Pistons for a 2025 NBA Cup group stage game on Wednesday, November 26. This would be the second occasion both teams will come against each other in the ongoing season. The Celtics are coming off an easy win over the Orlando Magic, whereas the Pistons are on a 13-game winning streak. Since the Celtics are trailing their head-to-head against the Pistons 0-1, they would aim to level the tally on Wednesday. 

Game Details 

Date: Wednesday, November 26, 2025
Time: 5 pm ET
Arena: TD Garden, Boston, Massachusetts
TV: FanDuel Sports Network
Live Stream: Fubo, NBA League Pass 

Recommended Bets and Odds 

Recommended Bets FanDuel BetMGM
Jaylen Brown O 26.5 points -130

Analysis and Rationale 

Jaylen Brown has been averaging 27.9 points per game through 17 outings in the NBA 2025-26 season. He is shooting at an impressive rate of 50.6% from the field and 34.4% from the three-point range. Playing an average of 32.4 minutes per night, Brown has scored 35 points against the Magic in their previous game while shooting 53.8% from the field and 33.3% from the three-point range. In fact, he has dropped 26 points or more in all four of his last games. Though the Pistons’ defense could come off as a challenge, Brown’s momentum and homecourt familiarity would help him finish over 26 points on Wednesday. 

Boston Celtics vs Detroit Pistons Predictions

Detroit Pistons are in a red-hot form in the 2025-26 season. They are leading the Eastern Conference with 15 wins in 17 games, and are coming off a seven-game winning streak. They rank eighth in scoring with an average of 119.6 points, and are leading the league in rebounding at an average of 49.1 rebounds per game. Not only this, but they are also among the top five when it comes to steals and blocks per game. 

When talking about their offensive and defensive ratings, the Pistons’ offensive rating of 117.3 gives them the eighth spot on the league, while a defensive rating of 110.4 has given them the third spot on the standings. 

On the other hand, the Celtics have slowly managed to get back on track after a few initial hiccups. However, it can still be said that they are not the same. The 18-time champions are without their star Jayson Tatum for most of the season. Not only this, but both Kristaps Porzingis and Al Horford left this past offseason. Though Brown has been leading the charts offensively, he is not a one-man show. Players such as Derrick White, Payton Pritchard, and Anfernee Simons have been solid contributors. 

Boston has been fighting inconsistency ever since the beginning of the season, and unfortunately, things are not going to get better for them anytime soon. Their center Neemias Queta has been sidelined with an ankle injury. Without Queta, Boston’s struggles on the defensive end will be more visible.

Talking about their stats, the Celtics are ranking fifth in terms of offensive rating at 118.8. However, their defensive rating of 114.0 puts them in the 16th spot on the standings. 

Considering the momentum, form, and availability of players, the Pistons are highly likely to come on top on Wednesday. However, we can expect a tough fight from the hosts as well.

Predictions: Boston Celtics to win. 

Boston Celtics vs Detroit Pistons Betting Odds and Spread 

Spread MoneylineTotal 
Boston Celtics +3 (-112)+126U 230.5 (-108)
Detroit Pistons -3 (-108)-148O 230.5 (-112)

Boston Celtics vs Detroit Pistons Over/Under Odds and Best Bets 

Boston Celtics Over/Under Odds 

Recommended Bets OverUnder 
Derrick White 16.5 points-114-114
Payton Pritchard 16.5 points -128-108
Derrick White 5.5 assists+130-174

Boston Celtics Best Bets 

Anfernee Simons to score 15+ points: +100
Payton Pritchard to hit 4+ made threes: +190
Jaylen Brown to record 6+ rebounds: -130

Detroit Pistons Over/Under Odds 

Recommended Bets OverUnder 
Cade Cunningham 25.5 points -120-110
Jalen Duren 19.5 points -108-122
Ausar Thompson 5.5 rebounds+128-172

Detroit Pistons Best Bets 

Jalen Duren to record 14+ rebounds: +132
Cade Cunningham to record a double-double: -110
Cade Cunningham to record 10+ assists: +102

The odds given above have been sourced from FanDuel. Use FanDuel to ace your betting game across all sports. 

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FAQs

What is the over/under for total points for the Celtics vs Pistons game?

The over/under for total points in the game between the Celtics and the Pistons is set at 230.5.

What is the point spread for the Celtics vs Pistons game?

The Pistons have a 3-point edge over the Celtics.

What is the moneyline for the Celtics vs Pistons game on Wednesday?

The Pistons are favorites to win with moneyline odds of -148, while the Celtics are underdogs at +126.