{"id":647719,"date":"2026-01-13T14:59:19","date_gmt":"2026-01-13T13:59:19","guid":{"rendered":"https:\/\/theplayoffs.news\/en\/?p=647719"},"modified":"2026-01-13T14:59:25","modified_gmt":"2026-01-13T13:59:25","slug":"denver-broncos-vs-buffalo-bills-opening-odds-early-picks-divisional-round","status":"publish","type":"post","link":"https:\/\/theplayoffs.news\/en\/denver-broncos-vs-buffalo-bills-opening-odds-early-picks-divisional-round\/","title":{"rendered":"NFL Divisional Round Lookahead \u2013 Denver Broncos vs Buffalo Bills Rams Opening Odds, Early Picks & Predictions"},"content":{"rendered":"

The first game of the Divisional round pits the Denver Broncos against the Buffalo Bills in what should be an exciting matchup between two top AFC teams.<\/p>

On one side, the Broncos are coming into the game off a bye as the number one seed in the AFC, while the Bills are coming into the game on the back of a thrilling road win against the Jacksonville Jaguars in the Wild Card round. <\/p>

The key to this exciting matchup will be Denver’s dominant defense against Buffalo’s offensive prowess, led by Josh Allen under center. <\/p>

What are the opening odds for the Broncos vs Bills?<\/h2>

The table below gives the opening odds for the Broncos<\/a> vs Bills<\/a> matchup as per FanDuel<\/a><\/strong>. <\/p>

<\/th>Spread<\/strong><\/th>Moneyline<\/strong><\/th>Total<\/strong><\/th><\/tr><\/thead>
Denver Broncos<\/strong><\/td>+1.5 (-110)<\/a><\/td>+104<\/a><\/td>O 46.5 (-110)<\/a><\/td><\/tr>
Buffalo Bills<\/strong><\/td>-1.5 (-110)<\/a><\/td>-122<\/a><\/td>U 46.5 (-110)<\/a><\/td><\/tr><\/tbody><\/table><\/figure>

The opening odds for the Broncos vs Bills Divisional round<\/a> matchup show that the Bills are the slight favorite to win the game.<\/p>

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Officially official.#BUFvsDEN<\/a> will kick off this Saturday at 2:30pm MT on CBS! pic.twitter.com\/WTfCOY13bt<\/a><\/p>— Denver Broncos (@Broncos) January 13, 2026<\/a><\/blockquote>