{"id":646759,"date":"2026-01-03T21:26:38","date_gmt":"2026-01-03T20:26:38","guid":{"rendered":"https:\/\/theplayoffs.news\/en\/?p=646759"},"modified":"2026-01-03T21:26:43","modified_gmt":"2026-01-03T20:26:43","slug":"49ers-vs-seahawks-predictions-odds-best-bets-week-18-nfl","status":"publish","type":"post","link":"https:\/\/theplayoffs.news\/en\/49ers-vs-seahawks-predictions-odds-best-bets-week-18-nfl\/","title":{"rendered":"San Francisco 49ers vs Seattle Seahawks Predictions, Odds, and Best Bets for Week 18 NFL 2025-26 Season"},"content":{"rendered":"<p>The <a href=\"https:\/\/theplayoffs.news\/en\/nfl\/\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>San Francisco 49ers<\/a> will host the Seattle Seahawks for an exciting NFC West clash featuring two elite teams. This 49ers vs Seahawks matchup features two teams dueling to determine who will win the NFC West division, as a lot lies on the line in this primetime showdown. <\/p><p>Both teams ride six-game winning streaks into this rematch of San Francisco&rsquo;s 17-13 Week 1 victory. The winner claims the division title, the NFC&rsquo;s No.1 seed. a first-round playoff bye, and home-field advantage throughout the postseason. The loser secures a wild-card spot but faces a tougher road path. Seattle&rsquo;s stout defense ranks second in points allowed, while the 49ers&rsquo; offense has surged lately behind Brock Purdy and Christian McCaffrey. <\/p><blockquote class=\"instagram-media\" data-instgrm-captioned data-instgrm-permalink=\"https:\/\/www.instagram.com\/p\/DS1dWqXFb6K\/?utm_source=ig_embed&amp;utm_campaign=loading\" data-instgrm-version=\"14\" style=\" background:#FFF; border:0; border-radius:3px; box-shadow:0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width:540px; min-width:326px; padding:0; width:99.375%; width:-webkit-calc(100% - 2px); width:calc(100% - 2px);\"><div style=\"padding:16px;\"> <a href=\"https:\/\/www.instagram.com\/p\/DS1dWqXFb6K\/?utm_source=ig_embed&amp;utm_campaign=loading\" style=\" background:#FFFFFF; line-height:0; padding:0 0; text-align:center; text-decoration:none; width:100%;\" target=\"_blank\" rel=\"noopener\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'> <div style=\" display: flex; flex-direction: row; align-items: center;\"> <div style=\"background-color: #F4F4F4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;\"><\/div> <div style=\"display: flex; flex-direction: column; flex-grow: 1; justify-content: center;\"> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;\"><\/div> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;\"><\/div><\/div><\/div><div style=\"padding: 19% 0;\"><\/div> <div style=\"display:block; height:50px; margin:0 auto 12px; width:50px;\"><svg width=\"50px\" height=\"50px\" viewbox=\"0 0 60 60\" version=\"1.1\" xmlns=\"https:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"https:\/\/www.w3.org\/1999\/xlink\"><g stroke=\"none\" stroke-width=\"1\" fill=\"none\" fill-rule=\"evenodd\"><g transform=\"translate(-511.000000, -20.000000)\" fill=\"#000000\"><g><path d=\"M556.869,30.41 C554.814,30.41 553.148,32.076 553.148,34.131 C553.148,36.186 554.814,37.852 556.869,37.852 C558.924,37.852 560.59,36.186 560.59,34.131 C560.59,32.076 558.924,30.41 556.869,30.41 M541,60.657 C535.114,60.657 530.342,55.887 530.342,50 C530.342,44.114 535.114,39.342 541,39.342 C546.887,39.342 551.658,44.114 551.658,50 C551.658,55.887 546.887,60.657 541,60.657 M541,33.886 C532.1,33.886 524.886,41.1 524.886,50 C524.886,58.899 532.1,66.113 541,66.113 C549.9,66.113 557.115,58.899 557.115,50 C557.115,41.1 549.9,33.886 541,33.886 M565.378,62.101 C565.244,65.022 564.756,66.606 564.346,67.663 C563.803,69.06 563.154,70.057 562.106,71.106 C561.058,72.155 560.06,72.803 558.662,73.347 C557.607,73.757 556.021,74.244 553.102,74.378 C549.944,74.521 548.997,74.552 541,74.552 C533.003,74.552 532.056,74.521 528.898,74.378 C525.979,74.244 524.393,73.757 523.338,73.347 C521.94,72.803 520.942,72.155 519.894,71.106 C518.846,70.057 518.197,69.06 517.654,67.663 C517.244,66.606 516.755,65.022 516.623,62.101 C516.479,58.943 516.448,57.996 516.448,50 C516.448,42.003 516.479,41.056 516.623,37.899 C516.755,34.978 517.244,33.391 517.654,32.338 C518.197,30.938 518.846,29.942 519.894,28.894 C520.942,27.846 521.94,27.196 523.338,26.654 C524.393,26.244 525.979,25.756 528.898,25.623 C532.057,25.479 533.004,25.448 541,25.448 C548.997,25.448 549.943,25.479 553.102,25.623 C556.021,25.756 557.607,26.244 558.662,26.654 C560.06,27.196 561.058,27.846 562.106,28.894 C563.154,29.942 563.803,30.938 564.346,32.338 C564.756,33.391 565.244,34.978 565.378,37.899 C565.522,41.056 565.552,42.003 565.552,50 C565.552,57.996 565.522,58.943 565.378,62.101 M570.82,37.631 C570.674,34.438 570.167,32.258 569.425,30.349 C568.659,28.377 567.633,26.702 565.965,25.035 C564.297,23.368 562.623,22.342 560.652,21.575 C558.743,20.834 556.562,20.326 553.369,20.18 C550.169,20.033 549.148,20 541,20 C532.853,20 531.831,20.033 528.631,20.18 C525.438,20.326 523.257,20.834 521.349,21.575 C519.376,22.342 517.703,23.368 516.035,25.035 C514.368,26.702 513.342,28.377 512.574,30.349 C511.834,32.258 511.326,34.438 511.181,37.631 C511.035,40.831 511,41.851 511,50 C511,58.147 511.035,59.17 511.181,62.369 C511.326,65.562 511.834,67.743 512.574,69.651 C513.342,71.625 514.368,73.296 516.035,74.965 C517.703,76.634 519.376,77.658 521.349,78.425 C523.257,79.167 525.438,79.673 528.631,79.82 C531.831,79.965 532.853,80.001 541,80.001 C549.148,80.001 550.169,79.965 553.369,79.82 C556.562,79.673 558.743,79.167 560.652,78.425 C562.623,77.658 564.297,76.634 565.965,74.965 C567.633,73.296 568.659,71.625 569.425,69.651 C570.167,67.743 570.674,65.562 570.82,62.369 C570.966,59.17 571,58.147 571,50 C571,41.851 570.966,40.831 570.82,37.631\"><\/path><\/g><\/g><\/g><\/svg><\/div><div style=\"padding-top: 8px;\"> <div style=\" color:#3897f0; font-family:Arial,sans-serif; font-size:14px; font-style:normal; font-weight:550; line-height:18px;\">View this post on Instagram<\/div><\/div><div style=\"padding: 12.5% 0;\"><\/div> <div style=\"display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;\"><div> <div style=\"background-color: #F4F4F4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);\"><\/div> <div style=\"background-color: #F4F4F4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;\"><\/div> <div style=\"background-color: #F4F4F4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);\"><\/div><\/div><div style=\"margin-left: 8px;\"> <div style=\" background-color: #F4F4F4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;\"><\/div> <div style=\" width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg)\"><\/div><\/div><div style=\"margin-left: auto;\"> <div style=\" width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);\"><\/div> <div style=\" background-color: #F4F4F4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);\"><\/div> <div style=\" width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);\"><\/div><\/div><\/div> <div style=\"display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;\"> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;\"><\/div> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;\"><\/div><\/div><\/a><p style=\" color:#c9c8cd; font-family:Arial,sans-serif; font-size:14px; line-height:17px; margin-bottom:0; margin-top:8px; overflow:hidden; padding:8px 0 7px; text-align:center; text-overflow:ellipsis; white-space:nowrap;\"><a href=\"https:\/\/www.instagram.com\/p\/DS1dWqXFb6K\/?utm_source=ig_embed&amp;utm_campaign=loading\" style=\" color:#c9c8cd; font-family:Arial,sans-serif; font-size:14px; font-style:normal; font-weight:normal; line-height:17px; text-decoration:none;\" target=\"_blank\" rel=\"noopener\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>A post shared by San Francisco 49ers (@49ers)<\/a><\/p><\/div><\/blockquote><script async src=\"\/\/www.instagram.com\/embed.js\"><\/script><h2 class=\"wp-block-heading\">Recommended Bets and Updated Odds<\/h2><figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th class=\"has-text-align-center\" data-align=\"center\">Recommended Bets<\/th><th class=\"has-text-align-center\" data-align=\"center\">Fanduel <\/th><th class=\"has-text-align-center\" data-align=\"center\">BetMGM<\/th><\/tr><\/thead><tbody><tr><td class=\"has-text-align-center\" data-align=\"center\">Sam Darnold over 30.5 passing attempts <\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-FanDuel-sports-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>-102<\/a><\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>-118<\/a><\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\">Christian McCaffrey over 18.5 rushing attempts<\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-FanDuel-sports-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>+102<\/a><\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>+100<\/a><\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\">Brock Purdy over 0.5 interceptions <\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-FanDuel-sports-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>-138<\/a><\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>-155<\/a><\/td><\/tr><\/tbody><\/table><\/figure><p>\n\n\n            <div class=\"MvpBookmakerTable\" >\n                                                            <div class=\"MvpBookmakerTableTopBlock\">\n                    <div class=\"MvpBookmakerTableTopBlock-item MvpBookmakerTableTopBlock-item--flex2\">\n                                    <div class=\"MvpBookmakerTableLogo\" style=\"background-color: #1493ff\">\n                <img decoding=\"async\" src=\"https:\/\/theplayoffs.news\/en\/wp-content\/uploads\/mm-business-data\/images\/brands\/9b4dabf72537-500-FanDuel.jpeg\" alt=\"FanDuel\">\n            <\/div>\n                                            <div class=\"MvpBookmakerTableTitleAndRate\">\n                <div class=\"MvpBookmakerTableTitleAndRate-title\">\n                    <div class=\"MvpBookmakerTableTitleAndRate-title-text\">\n                        FanDuel                    <\/div>\n           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Must be 21+ in most jurisdictions, but 18+ in DC, KY, and WY. Offer is valid only in eligible regulated states\/jurisdictions and not available in AR; void where prohibited. First online real-money wager only; cashed-out or bonus-funded bets are excluded.            <\/div>\n                                                    <\/div>\n            \n\n\n\n<\/p><h2 class=\"wp-block-heading\">Rationale and Analysis<\/h2><p>Sam Darnold has only thrown the football six times over 30.5 passing attempts this season. However, looking at the 49ers&rsquo; passing defense which has taken a huge hit since the last time they faced each other, giving up 235.6 yards per game, we expect Darnold to throw the football more in this game. In their earlier matchup in Week 1, Darnold only attempted 23 passes which resulted in a loss, and you can expect the gameplan to change in this game as they are battling for the top seed at NFC West division. <\/p><p>While the Seahawks have a strong rushing defense that only allows 94.4 yards per game, McCaffrey has exploded offensively in the last two weeks, posting  117 yards against the Colts, and 140 yards against the Bears last week, with a rushing touchdown and 2 receiving TDs. And in his last five games, McCaffrey has at least 20 or more attempts. With his recent performance, we expect the 49ers to go right back to him, potentially crossing 18.5 attempts in this game.<\/p><p>Brock Purdy has been amazing in the games he&rsquo;s played this season but has been unable to control turnovers. He&rsquo;s notched 9 interceptions in 8 games this season, with an interception each in the last two weeks. The Seahawks thrive on picks and are 5th in the league this season in total interceptions caught this season with 17, making Purdy possibly throwing above 0.5 interceptions a reasonable bet. <\/p><h2 class=\"wp-block-heading\">49ers vs Seahawks Prediction<\/h2><p>In this NFC West title decider with the No.1 seed on the line, the Seattle Seahawks visit the <a href=\"https:\/\/theplayoffs.news\/en\/nfl\/\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>San Francisco 49ers<\/a> riding matching six-game win streaks. Seattle boasts the league&rsquo;s second-ranked defense in points allowed and a balanced attack led by Sam Darnold, while the 49ers&rsquo; explosive offensive, averaging over 40 points lately, faces pressure against that stout unit. <\/p><p>Despite home-field advantage and Brock Purdy&rsquo;s surge with Christian McCaffrey, San Francisco&rsquo;s injury-depleted defense struggles with pass rush. And the more complete Seahawks may prevail despite being on the road. <\/p><p><strong>Prediction: Seattle Seahawks win 27-24<\/strong><\/p><blockquote class=\"instagram-media\" data-instgrm-captioned data-instgrm-permalink=\"https:\/\/www.instagram.com\/p\/DTDm8H_j40b\/?utm_source=ig_embed&amp;utm_campaign=loading\" data-instgrm-version=\"14\" style=\" background:#FFF; border:0; border-radius:3px; box-shadow:0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width:540px; min-width:326px; padding:0; width:99.375%; width:-webkit-calc(100% - 2px); width:calc(100% - 2px);\"><div style=\"padding:16px;\"> <a href=\"https:\/\/www.instagram.com\/p\/DTDm8H_j40b\/?utm_source=ig_embed&amp;utm_campaign=loading\" style=\" background:#FFFFFF; line-height:0; padding:0 0; text-align:center; text-decoration:none; width:100%;\" target=\"_blank\" rel=\"noopener\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'> <div style=\" display: flex; flex-direction: row; align-items: center;\"> <div style=\"background-color: #F4F4F4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;\"><\/div> <div style=\"display: flex; flex-direction: column; flex-grow: 1; justify-content: center;\"> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;\"><\/div> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;\"><\/div><\/div><\/div><div style=\"padding: 19% 0;\"><\/div> <div style=\"display:block; height:50px; margin:0 auto 12px; width:50px;\"><svg width=\"50px\" height=\"50px\" viewbox=\"0 0 60 60\" version=\"1.1\" xmlns=\"https:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"https:\/\/www.w3.org\/1999\/xlink\"><g stroke=\"none\" stroke-width=\"1\" fill=\"none\" fill-rule=\"evenodd\"><g transform=\"translate(-511.000000, -20.000000)\" fill=\"#000000\"><g><path d=\"M556.869,30.41 C554.814,30.41 553.148,32.076 553.148,34.131 C553.148,36.186 554.814,37.852 556.869,37.852 C558.924,37.852 560.59,36.186 560.59,34.131 C560.59,32.076 558.924,30.41 556.869,30.41 M541,60.657 C535.114,60.657 530.342,55.887 530.342,50 C530.342,44.114 535.114,39.342 541,39.342 C546.887,39.342 551.658,44.114 551.658,50 C551.658,55.887 546.887,60.657 541,60.657 M541,33.886 C532.1,33.886 524.886,41.1 524.886,50 C524.886,58.899 532.1,66.113 541,66.113 C549.9,66.113 557.115,58.899 557.115,50 C557.115,41.1 549.9,33.886 541,33.886 M565.378,62.101 C565.244,65.022 564.756,66.606 564.346,67.663 C563.803,69.06 563.154,70.057 562.106,71.106 C561.058,72.155 560.06,72.803 558.662,73.347 C557.607,73.757 556.021,74.244 553.102,74.378 C549.944,74.521 548.997,74.552 541,74.552 C533.003,74.552 532.056,74.521 528.898,74.378 C525.979,74.244 524.393,73.757 523.338,73.347 C521.94,72.803 520.942,72.155 519.894,71.106 C518.846,70.057 518.197,69.06 517.654,67.663 C517.244,66.606 516.755,65.022 516.623,62.101 C516.479,58.943 516.448,57.996 516.448,50 C516.448,42.003 516.479,41.056 516.623,37.899 C516.755,34.978 517.244,33.391 517.654,32.338 C518.197,30.938 518.846,29.942 519.894,28.894 C520.942,27.846 521.94,27.196 523.338,26.654 C524.393,26.244 525.979,25.756 528.898,25.623 C532.057,25.479 533.004,25.448 541,25.448 C548.997,25.448 549.943,25.479 553.102,25.623 C556.021,25.756 557.607,26.244 558.662,26.654 C560.06,27.196 561.058,27.846 562.106,28.894 C563.154,29.942 563.803,30.938 564.346,32.338 C564.756,33.391 565.244,34.978 565.378,37.899 C565.522,41.056 565.552,42.003 565.552,50 C565.552,57.996 565.522,58.943 565.378,62.101 M570.82,37.631 C570.674,34.438 570.167,32.258 569.425,30.349 C568.659,28.377 567.633,26.702 565.965,25.035 C564.297,23.368 562.623,22.342 560.652,21.575 C558.743,20.834 556.562,20.326 553.369,20.18 C550.169,20.033 549.148,20 541,20 C532.853,20 531.831,20.033 528.631,20.18 C525.438,20.326 523.257,20.834 521.349,21.575 C519.376,22.342 517.703,23.368 516.035,25.035 C514.368,26.702 513.342,28.377 512.574,30.349 C511.834,32.258 511.326,34.438 511.181,37.631 C511.035,40.831 511,41.851 511,50 C511,58.147 511.035,59.17 511.181,62.369 C511.326,65.562 511.834,67.743 512.574,69.651 C513.342,71.625 514.368,73.296 516.035,74.965 C517.703,76.634 519.376,77.658 521.349,78.425 C523.257,79.167 525.438,79.673 528.631,79.82 C531.831,79.965 532.853,80.001 541,80.001 C549.148,80.001 550.169,79.965 553.369,79.82 C556.562,79.673 558.743,79.167 560.652,78.425 C562.623,77.658 564.297,76.634 565.965,74.965 C567.633,73.296 568.659,71.625 569.425,69.651 C570.167,67.743 570.674,65.562 570.82,62.369 C570.966,59.17 571,58.147 571,50 C571,41.851 570.966,40.831 570.82,37.631\"><\/path><\/g><\/g><\/g><\/svg><\/div><div style=\"padding-top: 8px;\"> <div style=\" color:#3897f0; font-family:Arial,sans-serif; font-size:14px; font-style:normal; font-weight:550; line-height:18px;\">View this post on Instagram<\/div><\/div><div style=\"padding: 12.5% 0;\"><\/div> <div style=\"display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;\"><div> <div style=\"background-color: #F4F4F4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);\"><\/div> <div style=\"background-color: #F4F4F4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;\"><\/div> <div style=\"background-color: #F4F4F4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);\"><\/div><\/div><div style=\"margin-left: 8px;\"> <div style=\" background-color: #F4F4F4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;\"><\/div> <div style=\" width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg)\"><\/div><\/div><div style=\"margin-left: auto;\"> <div style=\" width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);\"><\/div> <div style=\" background-color: #F4F4F4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);\"><\/div> <div style=\" width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);\"><\/div><\/div><\/div> <div style=\"display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;\"> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;\"><\/div> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;\"><\/div><\/div><\/a><p style=\" color:#c9c8cd; font-family:Arial,sans-serif; font-size:14px; line-height:17px; margin-bottom:0; margin-top:8px; overflow:hidden; padding:8px 0 7px; text-align:center; text-overflow:ellipsis; white-space:nowrap;\"><a href=\"https:\/\/www.instagram.com\/p\/DTDm8H_j40b\/?utm_source=ig_embed&amp;utm_campaign=loading\" style=\" color:#c9c8cd; font-family:Arial,sans-serif; font-size:14px; font-style:normal; font-weight:normal; line-height:17px; text-decoration:none;\" target=\"_blank\" rel=\"noopener\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>A post shared by Seattle Seahawks (@seahawks)<\/a><\/p><\/div><\/blockquote><script async src=\"\/\/www.instagram.com\/embed.js\"><\/script><h2 class=\"wp-block-heading\">49ers vs Seahawks Spread and Betting Odds<\/h2><p>Looking at the spread and the moneyline, the <a href=\"https:\/\/theplayoffs.news\/en\/nfl\/\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>Seattle Seahawks<\/a> are the slight favorites to win the matchup against the San Francisco 49ers, as per <strong><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>BetMGM<\/a><\/strong>.<\/p><figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th class=\"has-text-align-center\" data-align=\"center\">Teams<\/th><th class=\"has-text-align-center\" data-align=\"center\">Spread<\/th><th class=\"has-text-align-center\" data-align=\"center\">Total Points<\/th><th class=\"has-text-align-center\" data-align=\"center\">Moneyline<\/th><\/tr><\/thead><tbody><tr><td class=\"has-text-align-center\" data-align=\"center\">Seahawks <\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>-2.5 (-115)<\/a><\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>47.5 (-110)<\/a><\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>-140<\/a><\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\">49ers<\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>+2.5 (-105)<\/a><\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>47.5 (-110)<\/a><\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>+115<\/a><\/td><\/tr><\/tbody><\/table><\/figure><p>\n\n\n            <div class=\"MvpBookmakerTable\" >\n                                                            <div class=\"MvpBookmakerTableTopBlock\">\n                    <div class=\"MvpBookmakerTableTopBlock-item MvpBookmakerTableTopBlock-item--flex2\">\n                                    <div class=\"MvpBookmakerTableLogo\" style=\"background-color: #000000\">\n                <img decoding=\"async\" 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1.23484 3.96797 1.94519 3.96797 2.81843C3.96797 3.02174 3.80457 3.18585 3.60215 3.18585C3.39973 3.18585 3.23633 3.02174 3.23633 2.81843C3.23633 1.5398 4.2716 0.5 5.54466 0.5H11.6905C12.9635 0.5 13.9988 1.5398 13.9988 2.81843V11.0315C13.9988 12.3102 12.9635 13.35 11.6905 13.35V13.3512Z\" fill=\"#002699\"\/>\n                            <\/g>\n                        <\/svg>\n                                    <\/div>\n            <\/div>\n                                                    <a rel=\"nofollow\"\n                        target=\"_blank\"\n                        href=\"\"\n                        class=\"MvpBookmakerTableCtaAndCode-top-cta\"\n                        data-cta-trk='{\"ctaBrand\":\"BetMGM\",\"ctaType\":\"Brand block\",\"ctaActivity\":\"sports\",\"ctaSubType\":\"main\"}'>\n                        <span>Claim now<\/span>\n                        <img decoding=\"async\" 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AZ\/CO\/IL\/IN\/IA\/KS\/LA\/MD\/MA\/MI\/NJ\/OH\/PA\/TN\/ VA\/WV\/WY only. Offer not available in DC\/MS\/NV\/NY\/PR. New customers only. Qualifying deposit (min $10) and first real money wager required. If qualifying bet settles as a loss, user is refunded 100% in non-withdrawable bonus bets up to $1,500. Full T&Cs can be found on betmgm.com.            <\/div>\n                                                    <\/div>\n            \n\n\n\n<\/p><h2 class=\"wp-block-heading\">49ers vs Seahawks Best Bets<\/h2><p>Here are the over\/under and best player bets for the San Francisco 49ers and the Seattle Seahawks, as per <strong><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>BetMGM<\/a><\/strong>.<\/p><h3 class=\"wp-block-heading\">San Francisco 49ers Over\/Under Odds<\/h3><p>Listed below are the over\/under bets for the San Francisco 49ers, as per <strong><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>BetMGM<\/a><\/strong>.<\/p><figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th class=\"has-text-align-center\" data-align=\"center\">Over\/Under Bets<\/th><th class=\"has-text-align-center\" data-align=\"center\">Over<\/th><th class=\"has-text-align-center\" data-align=\"center\">Under<\/th><\/tr><\/thead><tbody><tr><td class=\"has-text-align-center\" data-align=\"center\">Brock Purdy interceptions thrown<\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>0.5 (-155)<\/a><\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>0.5 (+115)<\/a><\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\">Brock Purdy passing TDs<\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>1.5 (-155)<\/a><\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>1.5 (+115)<\/a><\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\">Jauan Jennings receptions made<\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>3.5 (-150)<\/a><\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>3.5 (+115)<\/a><\/td><\/tr><\/tbody><\/table><\/figure><h3 class=\"wp-block-heading\">San Francisco 49ers Best Player Bets<\/h3><p>Here are some of the best player bets for the <a href=\"https:\/\/theplayoffs.news\/en\/nfl\/\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>San Francisco 49ers<\/a>, as per <strong><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>BetMGM<\/a><\/strong>.<\/p><ul class=\"wp-block-list\">\n<li>Christian McCaffrey anytime TD scorer: <a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>-175<\/a><\/li>\n\n\n\n<li>Brock Purdy over 0.5 interceptions thrown: <a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>-155<\/a><\/li>\n\n\n\n<li>Brock Purdy over 1.5 passing TDs: <a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>-155<\/a><\/li>\n<\/ul><h3 class=\"wp-block-heading\">Seattle Seahawks Over\/Under Odds<\/h3><p>Listed below are the over\/under odds for the Seattle Seahawks, as per <strong><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>BetMGM<\/a><\/strong>.<\/p><figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th class=\"has-text-align-center\" data-align=\"center\">Over\/Under Odds<\/th><th class=\"has-text-align-center\" data-align=\"center\">Over<\/th><th class=\"has-text-align-center\" data-align=\"center\">Under<\/th><\/tr><\/thead><tbody><tr><td class=\"has-text-align-center\" data-align=\"center\">Sam Darnold passing TDs<\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>1.5 (-150)<\/a><\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>1.5 (+110)<\/a><\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\">Sam Darnold interceptions thrown <\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>0.5 (-140)<\/a><\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>0.5 (+105)<\/a><\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\">Jaxson Smith-Njigba receptions made<\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>7.5 (-105)<\/a><\/td><td class=\"has-text-align-center\" data-align=\"center\"><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>7.5 (-125)<\/a><\/td><\/tr><\/tbody><\/table><\/figure><h3 class=\"wp-block-heading\">Seattle Seahawks Best Player Bets<\/h3><p>Here are some of the best player bets for the Seattle Seahawks, as per <strong><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>BetMGM<\/a><\/strong>.<\/p><ul class=\"wp-block-list\">\n<li>Jaxson Smith-Njigba anytime TD scorer: <a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>-115<\/a><\/li>\n\n\n\n<li>Zach Charbonnet anytime TD scorer: <a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>+110<\/a><\/li>\n\n\n\n<li>Sam Darnold over 1.5 passing TDs: <a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-sportsbetting-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>-150<\/a><\/li>\n<\/ul><p>\n\n\n            <div class=\"MvpBookmakerTable\" >\n                                                            <div class=\"MvpBookmakerTableTopBlock\">\n                    <div class=\"MvpBookmakerTableTopBlock-item MvpBookmakerTableTopBlock-item--flex2\">\n                                    <div class=\"MvpBookmakerTableLogo\" style=\"background-color: #000000\">\n                <img decoding=\"async\" src=\"https:\/\/theplayoffs.news\/en\/wp-content\/uploads\/mm-business-data\/images\/brands\/b6b0a2feb72c-500-BetMGM.jpg\" alt=\"BetMGM\">\n            <\/div>\n                                            <div class=\"MvpBookmakerTableTitleAndRate\">\n                <div class=\"MvpBookmakerTableTitleAndRate-title\">\n                    <div class=\"MvpBookmakerTableTitleAndRate-title-text\">\n                        BetMGM                    <\/div>\n                <\/div>\n                <div class=\"MvpBookmakerTableTitleAndRate-rate\">\n                            <div class=\"MvpRating\">\n    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8.45414 4.38475H2.30834V4.38352Z\" fill=\"#002699\"\/>\n                                <path d=\"M11.6905 13.3512C11.488 13.3512 11.3246 13.1871 11.3246 12.9838C11.3246 12.7805 11.488 12.6164 11.6905 12.6164C12.5599 12.6164 13.2672 11.906 13.2672 11.0328V2.81843C13.2672 1.94519 12.5599 1.23484 11.6905 1.23484H5.54466C4.67523 1.23484 3.96797 1.94519 3.96797 2.81843C3.96797 3.02174 3.80457 3.18585 3.60215 3.18585C3.39973 3.18585 3.23633 3.02174 3.23633 2.81843C3.23633 1.5398 4.2716 0.5 5.54466 0.5H11.6905C12.9635 0.5 13.9988 1.5398 13.9988 2.81843V11.0315C13.9988 12.3102 12.9635 13.35 11.6905 13.35V13.3512Z\" fill=\"#002699\"\/>\n                            <\/g>\n                        <\/svg>\n                                    <\/div>\n            <\/div>\n                                                    <a rel=\"nofollow\"\n                        target=\"_blank\"\n                        href=\"\"\n                        class=\"MvpBookmakerTableCtaAndCode-top-cta\"\n        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AZ\/CO\/IL\/IN\/IA\/KS\/LA\/MD\/MA\/MI\/NJ\/OH\/PA\/TN\/ VA\/WV\/WY only. Offer not available in DC\/MS\/NV\/NY\/PR. New customers only. Qualifying deposit (min $10) and first real money wager required. If qualifying bet settles as a loss, user is refunded 100% in non-withdrawable bonus bets up to $1,500. Full T&Cs can be found on betmgm.com.            <\/div>\n                                                    <\/div>\n            \n\n\n\n<\/p><p><em>(According to BetMGM: <strong><a href=\"https:\/\/theplayoffs.news\/en\/go-betmgm-prono-us-en\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>BetMGM<\/a><\/strong> offers exclusive promo codes, bonus deals and accurate odds for users upon signing up. Use BetMGM to ace your betting game in all sports!)<\/em><\/p><h2 class=\"wp-block-heading\">FAQs<\/h2><p id=\"block-98ac845e-ccee-4abb-ba3b-c51059c710da\"><strong>Who is favored to win between the 49ers vs Seahawks?<br><\/strong>The Seahawks are 2.5-point favorites to win the matchup against 49ers.<\/p><p id=\"block-4cee5a63-7364-47ec-b826-783765c73bc1\"><strong>What is the over\/under total for the game?<br><\/strong>The over\/under for total points is set at 47.5.<\/p><p id=\"block-2eade39d-dd77-4c9b-8b13-ebdde151d97f\"><strong>What is the predicted score for the 49ers vs Seahawks game?<\/strong><br>We expect the Seahawks to take down the 49ers in a close victory, and the Final score to be 27-24.<\/p>\n<div class=\"mm-layout mm-layout-type-global mm-layout-slot4\">\n<\/div>","protected":false},"excerpt":{"rendered":"<p>The San Francisco 49ers will host the Seattle Seahawks for an exciting NFC West clash featuring two elite teams. This 49ers vs Seahawks matchup features two teams dueling to determine who will win the NFC West division, as a lot lies on the line in this primetime showdown. Both teams ride six-game winning streaks into [&hellip;]<\/p>\n","protected":false},"author":19,"featured_media":646760,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"page-betting.php","format":"standard","meta":{"_acf_changed":false,"_mux_skip_reasons":[],"footnotes":""},"categories":[3,2590],"tags":[82,264,744],"class_list":["post-646759","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nfl","category-nfl-predictions","tag-nfl","tag-san-francisco-49ers","tag-seattle-seahawks"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>San Francisco 49ers vs Seattle Seahawks Predictions, Odds, and Best Bets for Week 18 NFL 2025-26 Season - The Playoffs<\/title>\n<meta name=\"description\" content=\"Get prediction, betting odds, best bets and more for the 49ers vs Seahawks week 18 NFL matchup of the 2025-26 season.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/theplayoffs.news\/en\/49ers-vs-seahawks-predictions-odds-best-bets-week-18-nfl\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"San Francisco 49ers vs Seattle Seahawks Predictions, Odds, and Best Bets for Week 18 NFL 2025-26 Season - 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